Research projects

This study identifies ribosomal DNA sequence variations and analyzes their functional consequences.

This study seeks to identify biomarkers predicting sensitivity to RNA Polymerase I (Pol I) inhibition to enhance patient stratification and treatment outcomes in cancer therapy.

Our project aims to identify how immune receptors and inflammasomes contribute to liver cancer development and potential therapies targeting these pathways to mitigate chronic inflammation and liver injury.

We wish to address gaps in capability by using accurate read-outs of translation efficiency available to us and developing methods for parallel extraction of structural, isoform and RNA-binding protein positional data, together with ligand-specific ribosome localisation read-outs.

This project focuses on Cancer/Testis (C/T) antigens and their function.

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Our research laboratory is dedicated to the in-depth exploration of the intricate interplay among platelet receptors, metalloproteases, and the surrounding plasma microenvironment.

This project focuses on the role of the histone variant H2A.B3 on spermatogenesis.

Leukemia Models

Despite only being discovered as recently as the turn of this century, miRNAs are already used in clinical trials as therapeutic candidates for complex diseases. Our research aims to characterise key miRNAs in the retina and exploit those as therapeutic molecules in the retina.

A multitude of brain cancer (glioma) mutations, identified by large-scale next generation sequencing (NGS), are predicted to drive disease through computational algorithms in silico.