This project uses next generation sequencing (NGS) and mass spectrometry to investigate the possible existence of regulatory interactions between ribonucleic acids, enzymes and metabolites to connect gene expression and metabolism

We've identified genetic factors contributing to kidney disease in the Australian Indigenous population and are creating mouse models and cell lines to study these genes and test potential treatments.

The aim of this project is to understand the ways in which astrocytes can sense the activity at adjacent synapses and how in-turn they can release substances that modulate these synapses.

The aim of this project is to identify glutamate recycling mechanisms and to discover their role in maintaining the supply of glutamate for continued neurotransmission.

A tool for temporally controlled, cell-type, and compartment-specific RNA isolation in neurons.

Our project investigates a novel DNA sensor's role in preventing cell proliferation and colorectal cancer by modulating immune responses and inflammation.

This project focuses on the molecular events by which maternal alcohol can affect the development of some but not all embryos.

This project focuses the role of H2A.B in Hodgkin Lymphoma.

This study identifies new cancer therapeutic targets within the RNA Polymerase I-specific transcription factor network to uncover potential innovative treatments.

This study identifies ribosomal DNA sequence variations and analyzes their functional consequences.

This study seeks to identify biomarkers predicting sensitivity to RNA Polymerase I (Pol I) inhibition to enhance patient stratification and treatment outcomes in cancer therapy.

Our project aims to identify how immune receptors and inflammasomes contribute to liver cancer development and potential therapies targeting these pathways to mitigate chronic inflammation and liver injury.

We wish to address gaps in capability by using accurate read-outs of translation efficiency available to us and developing methods for parallel extraction of structural, isoform and RNA-binding protein positional data, together with ligand-specific ribosome localisation read-outs.