Neutrophils and their extracellular traps in MS pathology

Our project investigates novel NLRP3 inhibitors to understand their efficacy in human cells and preclinical models of chronic inflammatory diseases.

Novel computational methods for long-read sequencing

We are exploring a number of therapeutic options, developed at ANU and by commercial partners, which include gene-based therapies, non-invasive therapeutics (including the use of low-level laser therapy using red light) and novel compounds.

Optimising the dose of 670nm light therapy for treatment of retinal degenerations

This project investigates miRNA profiles in human trabecular bone, synovial fluid and plasma sourced from total join replacement revision surgery, to develop better markers, treatments and prevention strategies.

Investigating the role of Spindle-E Zinc Finger motif in piRNA ping-pong biogenesis

RNA Sequencing with Oxford Nanopore Technologies produces a stream of signals that can be decoded to uncover the properties of individual molecules.

Quantitative studies of the presentation of viral antigens to the immune system (especially CD8+ T cells) during infection.

Major questions about the molecular mechanisms of rapid stress adaptation remain unanswered.

This project will examine the function of the variety of amino acid transporters found in neuronal tissue.