Projects

Find all JCSMR research projects.

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Studying the interaction between genes and environment in Indigenous Kidney Disease Potential
Synthetic platelet microbicidal peptides as novel anti-malarial drugs Potential
T cell responses to malaria Potential
Test novel mucosal vaccine adjuvants to enhance mucosal B and T cell immunity against mucosal pathogens Current
Testing compounds that may have pro- or anti-angiogenic activities Current
The contribution of platelets and/or neutrophils to diabetes development Current
The development of low-dose IL-2 therapy for inflammatory and autoimmune diseases Current
The development of superagonist monoclonal antibodies to human IL-21 in immunotherapy for infection and cancer Current
The differentiation and function of follicular cytotoxic T (Tfc) cells in infection and cancer Current
The regulation of follicular helper T (Tfh) cells in vaccination and autoimmune diseases Current
The role of chromatin in the repression of pervasive transcription Current
The role of heparanase in Type 1 diabetes Current
The role of oxidative stress in the progression of retinal degenerations Current
The role of pervasive transcription in genomic instability and how it contributes to cancer development Current
The role of platelets in the protection against malarial infection Potential
The spatial frequency doubling illusion Current
The use of miRNA as potential therapeutic targets in diseases causing retinal degenerations Current
Tissue specific factors of Th17cell mediated autoimmunity Current
To determine the role of histone variants, and other important epigenetic regulators, in regulating gene transcription and splicing. Potential
To elucidate the role of the epigenome, including the histone variant H2A.Z, in regulating the 3-dimensional architecture of the genome by inhibiting the expression of epigenetic regulators cellular differentiation. Potential
To study the role of histone variants and other epigenetic regulators in controlling pre-mRNA splicing on brain function and spermatogenesis using mouse knockout models. Potential
Tracking ribosome footprints to reveal the intricacy and control of translation Potential
Transcriptional control of the MYC oncogene Current
Translational control in cancer. Current
Uncover the mechanism of novel splicing “rescue” pathways Current

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