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Associate Professor Jean Wen obtained her PhD from the Australian National University (ANU). Following her doctoral studies, she undertook a postdoctoral position with Professor Anders Krogh at the Bioinformatics Centre of the University of Copenhagen, Denmark, and a research fellow position with Professor Eric Lai at the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, US. After being awarded a prestigious ARC Future Fellowship, she returned to ANU in 2018 to establish her own independent research group at the John Curtin School of Medical Research.

At the intersection of advanced computational biology and RNA biology, The Wen Group integrates innovative machine learning models with cutting-edge high-throughput assays to quantitatively model diverse modes of RNA-mediated gene regulatory interactions. These include mRNA diversity, RNA-binding proteins, miRNAs, small interfering RNAs, RNA modifications, and highly-conserved structural RNAs. Our goal is to understand how these RNA-mediated interactions control gene expression and cellular identity, how their misregulation can lead to disease, and to advance our understanding of cellular processes related to health and disease. Ultimately, we aim to contribute to breakthroughs in RNA-based technologies for treating a wide range of diseases.

Join our dynamic team! We are seeking dedicated PhD and Honours/Masters students with backgrounds in bioinformatics, computer science, or statistics for our interdisciplinary team. Email us at Jiayu.Wen@anu.edu.au.

Research Centres

• ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems (MACSYS), ANU Node Leader
• The Shine-Dalgarno Centre for RNA Innovation, Deputy Director
• Centre for Computational Biomedical Sciences, Member