This project aims to obtain comprehensive label free nanoscopic to microscopic structural information on how single cells form multicellular structures.

Neutrophils and their extracellular traps in MS pathology

Novel computational methods for long-read sequencing

We are exploring a number of therapeutic options, developed at ANU and by commercial partners, which include gene-based therapies, non-invasive therapeutics (including the use of low-level laser therapy using red light) and novel compounds.

We study how nuclear RNAs are processed, surveilled, and selectively exported, and how non-coding RNAs and R-loops shape genome organisation and stability. By defining the logic of nuclear RNA fate decisions, we aim to understand how RNA systems maintain genome integrity and contribute to disease.

Optimising the dose of 670nm light therapy for treatment of retinal degenerations

Pathogenic effects of cancer-associated mutations in IRF4

RNA Sequencing with Oxford Nanopore Technologies produces a stream of signals that can be decoded to uncover the properties of individual molecules.