Phenomics & Genomics

Next-generation sequencing technology and bioinformatics have opened up a new dimension for integrating phenomics, molecular biology, and systems biology for mouse and human. Our highly validated pipeline will accurately identify your variants using the following services.

Bioinformatics »

The APF team specializes in helping you to translate large, unwieldy sequencing datasets into manageable information in days, not months.

Cryopreservation »

The Australian Phenome Bank handles all ordering requests. Please visit the Australian Phenome Bank website for further information.

Exome and whole genome sequencing »

The Australian Phenomics Facility experienced team of genomic and bioinformatic specialists offer exome and whole genome service packages built around researcher “end-to-end” requirements and provide a number of tools not otherwise available in a standard sequencing service.

Genotyping »

The Australian Phenomics Facility experienced team of genomic and bioinformatic specialists offer exome and whole genome service packages built around researcher “end-to-end” requirements and provide a number of tools not otherwise available in a standard sequencing service.

In vitro fertilisation »

In vitro fertilisation (IVF) is used to re-animate strains from the frozen state from sources such as the repository of the Australian Phenome Bank. The team is using the latest and most efficient IVF techniques and re-animation success is currently running at 97% of attempts with sperm thawed from the APB archive.

Linkage analysis »

We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.

Phenotyping »

We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.

Rederivation »

Depending on their housing and transportation conditions mouse strains may be carrying a multitude of pathogens that may or may not result in disease but may very well affect your experimental result outcomes.

Single nucleotide variant validation »

We validate any SNVs identified through exome, whole genome or targeted sequencing.