High-throughput compound screening for therapeutic discovery is a critical process in drug development that allows researchers to quickly assess thousands of chemical compounds for their potential to interact with biological targets associated with specific diseases. By using automated systems and advanced robotics, this method accelerates the identification of compounds that exhibit desirable therapeutic effects, such as inhibiting a disease-related protein or activating a beneficial cellular pathway. Once promising compounds are identified, they can be further optimized and tested in preclinical and clinical settings, making high-throughput screening an essential tool for discovering new treatments for a wide range of diseases, including cancer, neurodegenerative disorders, and infectious diseases.

Compounds Australia Open Access Libraries

We order customised assay-ready compound plates from Compounds Australia including open access drug libraries, open access scaffold libraries, NatureBank and Australian Lead Identification Consortium. 

NCI Program for Natural Product Discovery (NPNPD)

The NCI Program for Natural Product Discovery (NPNPD) is a national program aimed to advance natural product technologies and facilitate the discovery of structurally defined, validated lead molecules ready for translation. NPNPD has created a pre-fractionated library of natural product extracts for high throughput screening and has made the initial release of 150,000 pre-fractionated samples available as a service to the research community. The library will eventually number ~1,000,000 total pre-fractionated samples which will all be made available. We are the only facility in Australia to have a collection of this library stored at Compounds Australia.