RNAi Screening

RNAi Screening

RNA interference (RNAi) screening is a technique used to knock down specific genes to study their function and identify potential therapeutic targets.

feed Service theme
meeting_room Facility
contact_support Contact
General Enquiries
actd.brf@anu.edu.au

Content navigation

About

RNA interference (RNAi) screening is used to study gene function by selectively silencing specific genes. By introducing small interfering RNA (siRNA) molecules into cells, RNAi screens can effectively reduce the expression of targeted genes, allowing researchers to observe the resulting phenotypic changes. This approach is widely used to identify genes involved in various biological processes, such as cell growth, signaling, and disease pathways, making it particularly valuable in drug discovery and the development of therapeutic interventions. Through high-throughput RNAi screening, scientists can systematically explore large gene sets to uncover novel targets for diseases like cancer, viral infections, and genetic disorders.

We have a collection of Horizon siGENOME Human siRNA Library (Arrayed) which is a SMARTpool of 4 siRNA for each gene target. 

Equipment

The Revvity Opera Phenix High-Content Imaging Microscope is an advanced imaging platform designed for high-throughput phenotypic screening, offering superior sensitivity and resolution for detailed cellular analysis in various research applications.

Read more