One core regulator of growth and division of great interest to our research is the MYC oncogene, which is a potent activator of cell growth networks and upregulated in most human cancers. This research aims to use a combination of models to unravel the mechanisms for regulation of MYC expression by FBP/FIR.

We wish to identify malignant-specific rapid responses to drug stress and find new compounds that would block such responses and reduce the adaptation rate.

We aim to molecularly characterise these newly emerging splicing regulations and to investigate their roles in non-germline tissues such as brain and muscles.

We aim to anatomically and molecularly identify the causative defects in the somatic development of piRNA pathway mutant ovaries.

study how new therapeutics that treat malignancy impact on platelet function and contribute to dysregulation of thrombopoiesis and haemostasis.

The Whole Cell Model Development project, spearheaded by our ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems (MACSYS), is dedicated to constructing mathematical and machine learning models of entire cells, known as Whole Cell Models (WCM).