Research projects
Explore our research projects and see how you can get involved.
Displaying 1 - 15 of 21 project(s).
This project focuses on how germ cells control the function of Sertoli cells.
Student intake
Open for Honours, PhD students
domain Division
villa Centre
Group
People
- Associate Professor Tanya Soboleva, Supervisor
This study aims to identify and understand mechanisms of intrinsic and acquired resistance to RNA Polymerase I (Pol I) inhibition in cancer, with the goal of developing strategies to overcome resistance to Pol I inhibitors.
Theme
- Phenogenomics
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Dr Nadine Hein, Supervisor
- Professor Ross Hannan, Supervisor
This study explores how dynamic changes in ribosomal DNA (rDNA) chromatin contribute to cancer development, aiming to uncover mechanisms of malignant transformation and potential therapeutic targets.
Theme
- Phenogenomics
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Dr Nadine Hein, Supervisor
- Professor Ross Hannan, Supervisor
This project focuses on the role of H2A.B in spermatogenesis under heat stress.
Student intake
Open for Honours, PhD students
domain Division
villa Centre
Group
People
- Associate Professor Tanya Soboleva, Supervisor
This study aims to develop effective combination therapies using RNA Polymerase I (Pol I) inhibitors to enhance therapeutic efficacy and combat resistance in cancer treatment through synergistic effects with other drugs or treatments.
Theme
- Phenogenomics
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Associate Professor Amee George, Supervisor
- Dr Rita Ferreira, Supervisor
- Professor Ross Hannan, Supervisor
This project focuses on understanding the role of WNT in congenital heart defects.
Student intake
Open for Honours, PhD students
domain Division
Group
People
- Professor Ruth Arkell, Supervisor
This study evaluates UBF (Upstream Binding Factor) as a potential target for cancer therapy by investigating its role in cancer cell growth and survival.
Theme
- Cancer
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Dr Rita Ferreira, Supervisor
- Professor Ross Hannan, Supervisor
This project uses next generation sequencing (NGS) and mass spectrometry to investigate the possible existence of regulatory interactions between ribonucleic acids, enzymes and metabolites to connect gene expression and metabolism
Student intake
Open for Honours, Masters, PhD students
domain Division
villa Centre
Group
People
- Professor Thomas Preiss, Supervisor
This project focuses the role of H2A.B in Hodgkin Lymphoma.
Student intake
Open for Honours, PhD students
domain Division
villa Centre
Group
People
- Associate Professor Tanya Soboleva, Supervisor
This study identifies new cancer therapeutic targets within the RNA Polymerase I-specific transcription factor network to uncover potential innovative treatments.
Theme
- Phenogenomics
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Dr Rita Ferreira, Supervisor
- Professor Ross Hannan, Supervisor
This study identifies ribosomal DNA sequence variations and analyzes their functional consequences.
Theme
- Phenogenomics
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Dr Nadine Hein, Supervisor
- Professor Eduardo Eyras, Supervisor
- Professor Ross Hannan, Supervisor
This study seeks to identify biomarkers predicting sensitivity to RNA Polymerase I (Pol I) inhibition to enhance patient stratification and treatment outcomes in cancer therapy.
Theme
- Phenogenomics
Student intake
Open for Honours, Masters, PhD students
domain Division
Group
People
- Dr Nadine Hein, Supervisor
- Professor Ross Hannan, Supervisor
This project focuses on Cancer/Testis (C/T) antigens and their function.
Student intake
Open for Honours, PhD students
domain Division
villa Centre
Group
People
- Associate Professor Tanya Soboleva, Supervisor
This project focuses on the role of the histone variant H2A.B3 on spermatogenesis.
Student intake
Open for Honours, PhD students
domain Division
villa Centre
Group
People
- Associate Professor Tanya Soboleva, Supervisor
Investigating the role of Spindle-E Zinc Finger motif in piRNA ping-pong biogenesis
Student intake
Open for Honours students
domain Division
villa Centre
Group
People
- Dr Rippei Hayashi, Supervisor
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