Phenogenomics

Research strength B

About

Research strength A

Groups

Ehsan Arabzadeh

The Neural Coding Group has a broad interest in systems neuroscience spanning areas such as sensory coding, adaptation and behaviour.

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Four women sitting and smiling

We aim to understand complex molecular processes by which these transcription factors interact with signal transduction pathways, chromatin and RNA.

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Bruestle

A special interest of this group is in type 3 immune responses including the CD4 subset of inflammatory Th17 cells, neutrophils and dendritic cells.

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The Fischer Group

The Fischer lab investigates the connection between chromatin structure, pervasive transcription and RNA surveillance, and their influence on genomic stability.

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George Group

Research group led by A/Prof Amee George.

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Ross Hannan lab 2024

This group focus on targeting the ribosome to treat disease including cancer and bone marrow disorders.

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Simon Jiang Group Personalised Medicine and Autoimmunity

Identifying the genetic and cellular causes of immune mediated disease to personalise diagnosis and treatment.

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Lipotek is a developer of targeted vaccine delivery and adjuvant technologies.

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Marshall Group

The Genomic Plasticity Lab studies how dynamic DNA structures and non-classical DNA modifications contribute to the formation and persistence of long-term memories, particularly in fear-related learning and memory.

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mcmorran

The main focus of our research group is to study red blood cells and platelets, exploring their roles in diseases, with projects available for students interested in immunology, parasitology, and human genetics.

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The Schulte group

The Schulte Group investigates therapy options arising from the nucleolar stress response.

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My research has been focused on degenerative diseases of the retina, from the molecular and cellular level to the clinical.

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Facilities

ACTD Robots

The ANU Centre for Therapeutic Discovery (ACTD) is a state-of-the-art high-throughput screening facility for biomarker and therapeutic discovery.

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Projects

This study aims to identify and understand mechanisms of intrinsic and acquired resistance to RNA Polymerase I (Pol I) inhibition in cancer, with the goal of developing strategies to overcome resistance to Pol I inhibitors.

Student intake

Open for Honours, Masters, PhD students

People

This study explores how dynamic changes in ribosomal DNA (rDNA) chromatin contribute to cancer development, aiming to uncover mechanisms of malignant transformation and potential therapeutic targets.

Student intake

Open for Honours, Masters, PhD students

People

This study aims to develop effective combination therapies using RNA Polymerase I (Pol I) inhibitors to enhance therapeutic efficacy and combat resistance in cancer treatment through synergistic effects with other drugs or treatments.

Student intake

Open for Honours, Masters, PhD students

People

We've identified genetic factors contributing to kidney disease in the Australian Indigenous population and are creating mouse models and cell lines to study these genes and test potential treatments.

This study identifies new cancer therapeutic targets within the RNA Polymerase I-specific transcription factor network to uncover potential innovative treatments.

Student intake

Open for Honours, Masters, PhD students

People

This study identifies ribosomal DNA sequence variations and analyzes their functional consequences.

Student intake

Open for Honours, Masters, PhD students

People

Members

Professional staff

Arash Araghi

Higher Degree Research Strategy Manager,
The Shine-Dalgarno Centre for RNA Innovation

Academic staff

Katrina Randall

Director, Canberra Clinical Phenomics Service
Associate Professor, ANU School of Medicine and Psychology
Staff Specialist in Immunology, Canberra Health Services

Paull Marshall

Group Leader

News

Zaka Yuen Eduardo Eyras Cameron Jack

In a groundbreaking study, Dr Zaka Yuen and collaborators at the John Curtin School of Medical Research (JCSMR) utilised nanopore adaptive sampling to identify DNA methylation markers related to age and body fluids.

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Thomas Preiss JCSMR ANU SDCRI

Scientists at The Shine-Dalgarno Centre for RNA Innovation (SDCRI) are teaming up with the community to unlock the full potential of ribonucleic acid (RNA). It could lead to breakthroughs in everything from cancer treatments and new therapies for complex diseases, to age-related macular degeneration and crop resilience.

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ANU 3MT Final 2024 - Rakshanya and Sasanan

Creating a historic moment for the John Curtin School of Medical Research (JCSMR), two of our outstanding PhD students Sasanan and Rakshanya claimed the winner and runner-up awards at the Australian National University (ANU) 3-Minute Thesis Competition 2024 grand finale, held on 25 July at Llewellyn Hall.

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Paul Marshall

A specific type of DNA structure could hold the key to regulating our memory, a new ANU study has shown.

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Assosicate Professor Simon Jiang

In a world where healthcare can feel impersonal, ANU researchers are making medical diagnoses at a genetic level and tailoring treatments to individuals like never before.

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