We're developing PDIP, a peptide derived from PF4, to combat malaria by targeting and killing parasites inside infected cells; current efforts focus on optimizing its structure and combining it with existing drugs for enhanced efficacy.

We've discovered that platelets help remove aged red blood cells by forming complexes that target them for destruction in the spleen, a process crucial for preventing thrombosis and maintaining red blood cell homeostasis.

The McMorran group discovered that platelets play a protective role in malaria by releasing Platelet factor 4 (PF4), which kills the parasite, and are currently studying the molecular mechanisms behind this function.

Our project explores novel antimicrobial peptides inspired by the immune system to understand their mechanism in combating antibiotic-resistant bacteria.

Our projects use advanced genomics, cellular immunology, and transcriptomics to investigate the unique causes of immune diseases in individuals, aiming to identify new treatment targets and improve patient outcomes.