CHASM

Cytometry, Histology and Spatial Multiomics

The Cytometry, Histology and Spatial Multiomics service provides access to equipment and on-going support, advice and training in cell sorting (FACS), flow cytometry analysers, imaging cytometry, data analysis, and Extracellular Flux Analyzer.

About

We provide access to equipment and on-going support, advice and training in the following areas: Cell sorting (FACS), flow cytometry analyzers, imaging cytometry, data analysis, and Extracellular Flux Analyzer.

Services

CHASM FUSION

High speed cell sorting by experienced facility staff.

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Spectral and conventional cell analysers.

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The ImageStream MkII is a multispectral, imaging flow cytometer that can acquire up to 12 channels of images.

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The CHASM facility provides access to software for FACS Data Analysis.

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Metabolism is a complex process that lies at the core of biology. Changes to metabolism are involved in a huge range of outcomes, from cancer to neurodegeneration, and more.

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Formalin fixed tissue processing
Paraffin embedding
FFPE Tissue sectioning
Frozen Tissue Sectioning
Immunohistochemistry - single and multiplex fluorescence and chromogenic staining
Routine H&E and histochemical staining (reagent dependent)

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CHASM Phenocycler

The Phenocycler-Fusion 2.0 (Akoya Biosciences) is the only end-to-end multiplexed immunofluorescence benchtop platform that can efficiently quantify cellular markers.

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Optical bioluminescent/fluorescence and micro CT.

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The CHASM facility provides access to a range of light microscopy techniques including confocal, multiphoton, live cell and intra-vital imaging.

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The CHASM facility provides access to software for image analysis.

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CHASM Mindray

The Mindray BC-5000 Vet is a haematology analyser that provides quick, low volume analysis of blood, serum and other samples. It provides accurate and reproducible measurements of RBCs, WBCs and platelets, for 23 parameters total.

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CHASM Zeta

Nanoparticle Tracking Analysis (NTA) has been used for concentration and size measurement of nanoparticles dispersed in a medium.

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