Linkage analysis

We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.

Our service offers:

  • Genome screens for mapping using fluorescent KASP single nucleotide variant (SNV) technology
  • Proximal/distal screen with markers at each end of the chromosomes plus one central to the longer chromosomes
  • Genome-wide (10-20Mb spacing) marker panels for various mapping crosses.
  • Additional fine mapping project markers
  • Custom design assays to SNVs in your mapped intervals.
  • Sanger re-sequencing of exons within a mapped interval. We have the ability to design primer for resequencing candidate genes or all exons within a defined interval.

DNA preparation: Crude-from ear punch (plate) »

DNA preparation -Crude-from ear punch (plate)

Please complete the appropriate form below and submit to the email contact provided above.