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Look for mutations in your gene of interest in the APF collections.
The Australian Phenome Bank (APB) is a centralised repository of genetically modified mouse strains and strain information used in Medical Research in Australia.
Libraries of mice are established using ENU-injected male mice, producing offspring which are heterozygous for random ENU-induced mutations in the genome.
Utilising whole exome sequencing and our N-ethyl-N-nitrosourea (ENU) mouse mutagenesis pipeline we are generating thousands of known missense and nonsense variants per year on the inbred C57BL/6 genetic background
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The Australian National University, Canberra
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