Why do live pathogens make better vaccines?

In this project you will address the fundamental question of why live pathogens induce durable B cell responses while dead or subunit vaccines induce only short-lived responses.

Using cutting edge technologies in the Cockburn (ANU) and Sander (Charite Universitatsmedizin, Berlin) laboratories you will investigate the different immune responses induced by different immunogens.

The ultimate aim of this project is to replicate the protection induced by a live pathogen with a safe subunit vaccine construct.

This project is part of the Crossing Boundaries: Molecular Interactions in Malaria Graduate SchoolParticipants study at both ANU and the Humboldt University in Berlin, earning a dual degree. Find out more.