A legacy of discovery: Celebrating Nobel laureate distinguished Professor Peter Doherty at JCSMR's 75th anniversary
As the John Curtin School of Medical Research (JCSMR) celebrates its 75th anniversary, Nobel Laureate Distinguished Professor Peter Doherty, a former JCSMR scientist, returned as the guest of honour at the celebratory symposium held on 24 October 2024, at the Finkel Lecture Theatre. His journey at JCSMR exemplifies a career of extraordinary scientific achievement, tenacity, and transformative insights. Reflecting on his formative years, Doherty recalls JCSMR as a uniquely dynamic environment that not only shaped his future but redefined his path in medical research.
Doherty's time at JCSMR in the Department of Microbiology from 1971 to 1975 marked his first foray into a rigorous research environment, a period he now views as the foundation of his scientific identity. He describes the intellectually stimulating "Bible Class" immunology discussion group led by the legendary Gordon Ada as a pivotal experience. “It was terrific,” Doherty recounts, explaining how the weekly meetings served as a model for fostering intellectual openness and critical inquiry. Ada’s spontaneous, hands-on support also left a lasting impact on Doherty’s approach to mentorship. “The lessons? Be generous and do it now! Don’t dither!” This ethos of immediacy and generosity would guide him throughout his career.
Professor Doherty in the lab during his early days at JCSMR, where his groundbreaking research journey began. Photo: JCSMR Archives
The intellectual rigor of JCSMR, coupled with Doherty's insatiable curiosity, laid the groundwork for the landmark discovery he made with Rolf Zinkernagel—work that would eventually earn them the Nobel Prize in Physiology or Medicine in 1996. This discovery, along with the theoretical foundations they explored at JCSMR, charted the course for Doherty’s research and solidified his reputation as a pioneer in immunology. "The basic science environment in Ada’s department gave me great independence and freedom of action," he reflects, noting the unique opportunity JCSMR provided to step beyond his initial veterinary training and dive into the uncharted territory of immunological research.
Peter Doherty and Rolf Zinkernagel, whose pioneering research at JCSMR led to a Nobel Prize in Physiology or Medicine. Photo: JCSMR Archives
However, the journey was not without its challenges. When Doherty transitioned from veterinary research on domestic animals to basic immunology at JCSMR, he found himself carving a path that no one with his background had pursued before. As the only veterinarian to have been awarded a Nobel Prize, Doherty faced the dual challenge of mastering an unfamiliar field while redefining his professional identity. But the collaborative environment at JCSMR was precisely what he needed to overcome these obstacles. The institute’s supportive culture allowed Doherty to thrive and, in his words, “move on from that” early work, with the confidence to explore more complex scientific questions.
Reflecting on the evolution of medical research, Doherty acknowledges the shift brought by molecular medicine, an era that has unveiled vast opportunities for research and practical application. He urges today’s researchers to remain adaptable and to embrace the R&D spectrum as a “broad church.” His message to young scientists at JCSMR is one of hope and encouragement: the possibilities today are greater than ever. However, he emphasises that this journey requires a balance between dedication to data and life outside the lab. “Work hard and smart,” he advises, “but as a lab researcher, love your data, live with your data, be instructed by nature.”
Professor Peter Doherty at the JCSMR 75th Anniversary Symposium, held on 24 October 2024, at the John Curtin School of Medical Research, ANU. Photos: Kassapa Senarath/ANU
Doherty’s journey is a testament to JCSMR’s enduring legacy. Over the years, the institute has continued to inspire and shape remarkable scientists whose discoveries make a lasting impact on human health. As JCSMR celebrates this milestone, Doherty’s return is both a tribute to the past and a reminder of the institute’s promise to future generations of researchers. “You’re in a great tradition,” he says to those following in his footsteps. “The ANU is the only Australian University that has been the workplace that set the stage for three quite different Nobel Prizes.”
In honouring Peter Doherty’s remarkable achievements and his ongoing commitment to science communication, JCSMR celebrates not only its past but also its vibrant present and promising future. His presence at the 75th anniversary underscores the institute’s dedication to advancing knowledge and innovation, a commitment that remains as robust today as it was when Doherty first walked through its doors.