Control of organ growth by the Hippo pathway

Abstract

Kieran’s team studies organ size control during development, using Drosophila, and how signalling pathways that control organ size are deregulated in human cancer. In particular, his group focuses on the Hippo pathway, which he helped to discover in the early 2000’s.

Recently, Kieran’s team has employed a number of high-resolution imaging approaches to gain new insights into how Hippo pathway activity is regulated during developmental organ growth and how the Hippo pathway controls transcription.

Biography

Professor Kieran Harvey holds dual appointments at the Peter MacCallum Cancer Centre, where he leads the Organogenesis and Cancer Program and Monash University, where he runs a laboratory in the Department of Anatomy and Developmental Biology.

Kieran performed Doctoral studies with Prof. Sharad Kumar (University of Adelaide) and postdoctoral studies with Prof. Iswar Hariharan (Massachusetts General Hospital/Harvard Medical Center and University of California, Berkeley). He holds an NHMRC Investigator grant and was awarded the Gottschalk Medal by the Australian Academy of Science in 2014, for outstanding research in the medical sciences. He is the current President of the Australia and New Zealand Society for Cell and Developmental Biology.