Studying histidine-rich glycoprotein (HRG)

For many years the Laboratory has been studying histidine-rich glycoprotein (HRG), a blood borne protein that binds heparan sulfate and many other ligands and has been implicated in tumour metastasis and angiogenesis. Research on this molecule continues, with our recent studies suggesting that HRG may play an important role in controlling autoimmune diseases, such as systemic lupus, by aiding the elimination of dead and dying cells.