Investigation of a role of H2A.B3 in piRNA biology

In spermatogenesis, which is our model cell differentiation system, H2A.B interacts with piRNA processing machinery within chromatoid bodies located outside of the nucleus of haploid round spermatids. The significance of this interaction is unclear and represent the avenue for investigation.

This project offers an all-rounding way to fully immerse students into scientific life, as it gives opportunity to master your experimental skills, learn some of the state-of-the-art techniques, as well as find out a lot about very exciting fields of biology, such as epigenetics spermatogenesis and how it can relate to cancer.