Services

Australian Phenome Bank »

The Australian Phenome Bank (APB) is a centralised repository of genetically modified mouse strains and strain information used in Medical Research in Australia.

Bioinformatics »

The APF team specializes in helping you to translate large, unwieldy sequencing datasets into manageable information in days, not months.

Colony maintenance »

You can manage the breeding of your strains remotely through the “Musterer” database or task your dedicated project manager and colony coordinator to undertake your breeding and sampling management.

Cryopreservation »

The Australian Phenome Bank handles all ordering requests. Please visit the Australian Phenome Bank website for further information.

ENU Screens »

Libraries of mice are established using ENU-injected male mice, producing offspring which are heterozygous for random ENU-induced mutations in the genome.

Exome and whole genome sequencing »

The Australian Phenomics Facility experienced team of genomic and bioinformatic specialists offer exome and whole genome service packages built around researcher “end-to-end” requirements and provide a number of tools not otherwise available in a standard sequencing service.

Genotyping »

The Australian Phenomics Facility experienced team of genomic and bioinformatic specialists offer exome and whole genome service packages built around researcher “end-to-end” requirements and provide a number of tools not otherwise available in a standard sequencing service.

Import and export »

The import and export team are highly experienced in all fields of domestic and international mouse movement.

In vitro fertilisation »

In vitro fertilisation (IVF) is used to re-animate strains from the frozen state from sources such as the repository of the Australian Phenome Bank. The team is using the latest and most efficient IVF techniques and re-animation success is currently running at 97% of attempts with sperm thawed from the APB archive.

Linkage analysis »

We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.

Missense Mutation Library »

Utilising whole exome sequencing and our N-ethyl-N-nitrosourea (ENU) mouse mutagenesis pipeline we are generating thousands of known missense and nonsense variants per year on the inbred C57BL/6 genetic background

Phenotyping »

We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.

Rederivation »

Depending on their housing and transportation conditions mouse strains may be carrying a multitude of pathogens that may or may not result in disease but may very well affect your experimental result outcomes.

Single nucleotide variant validation »

We validate any SNVs identified through exome, whole genome or targeted sequencing.

Technical support »

In addition to the care and attention to detail provided by the APF animal services team our highly trained technical staff provide a range of services to compliment your research needs.