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Services
Australian Phenome Bank »
The Australian Phenome Bank (APB) is a centralised repository of genetically modified mouse strains and strain information used in Medical Research in Australia.
Bioinformatics »
The APF team specializes in helping you to translate large, unwieldy sequencing datasets into manageable information in days, not months.
Canberra Clinical Phenomics Service (CCPS) »
The Canberra Clinical Phenomics Service provides specialised analysis of human blood samples for markers of immune and inflammatory conditions.
Colony maintenance »
You can manage the breeding of your strains remotely through the “Musterer” database or task your dedicated project manager and colony coordinator to undertake your breeding and sampling management.
Cryopreservation »
The Australian Phenome Bank handles all ordering requests. Please visit the Australian Phenome Bank website for further information.
ENU Screens »
Libraries of mice are established using ENU-injected male mice, producing offspring which are heterozygous for random ENU-induced mutations in the genome.
Exome and whole genome sequencing »
The Australian Phenomics Facility experienced team of genomic and bioinformatic specialists offer exome and whole genome service packages built around researcher “end-to-end” requirements and provide a number of tools not otherwise available in a standard sequencing service.
Import and export »
The import and export team are highly experienced in all fields of domestic and international mouse movement.
In vitro fertilisation »
In vitro fertilisation (IVF) is used to re-animate strains from the frozen state from sources such as the repository of the Australian Phenome Bank. The team is using the latest and most efficient IVF techniques and re-animation success is currently running at 97% of attempts with sperm thawed from the APB archive.
Linkage analysis »
We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.
Missense Mutation Library »
Utilising whole exome sequencing and our N-ethyl-N-nitrosourea (ENU) mouse mutagenesis pipeline we are generating thousands of known missense and nonsense variants per year on the inbred C57BL/6 genetic background
Phenotyping »
We provide space, equipment and expertise to run small or large projects to map the chromosomal location and identify the affected gene of new gene-variant mouse strains obtained from N-ethyl-N-nitrosourea (ENU) libraries, spontaneous mutations or causative polymorphisms.
Rederivation »
Depending on their housing and transportation conditions mouse strains may be carrying a multitude of pathogens that may or may not result in disease but may very well affect your experimental result outcomes.
Single nucleotide variant validation »
We validate any SNVs identified through exome, whole genome or targeted sequencing.
Technical support »
In addition to the care and attention to detail provided by the APF animal services team our highly trained technical staff provide a range of services to compliment your research needs.
