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A novel mechanism of epigenetic information transfer between different cell types |
Potential |
|
Characterisation of the role of H2A.B spermatogenesis during heat stress |
Potential |
|
Click chemistry enables evaluation of the molecular mechanism of the 2nd generation RNA polymerase I inhibitor, PMR-116 |
Current |
|
Embryonic development: How does elevated Wnt signalling cause heart defects? |
Potential |
|
Gene regulation through interactions between RNA, enzymes and metabolites |
Potential |
|
How does alcohol combine with genetics to alter brain development? |
Potential |
|
How is H2A.B involved in Hodgkin lymphoma carcinogenesis? |
Potential |
|
Innovative methods to detect rapid translational control. |
Current |
|
Investigating a role of C/T antigens in spermatogenesis and cancer |
Potential |
|
Investigation of a role of H2A.B3 in piRNA biology |
Potential |
|
Novel algorithms to study transcriptome variation with long-read sequencing |
Current |
|
Potential role of phase separation in transposon defence |
Potential |
|
Predictive models of RNA biochemical modifications and their role in RNA processing |
Current |
|
Rapid translation-based stress responses to environmental changes. |
Current |
|
To determine the role of histone variants, and other important epigenetic regulators, in regulating gene transcription and splicing. |
Potential |
|
To elucidate the role of the epigenome, including the histone variant H2A.Z, in regulating the 3-dimensional architecture of the genome by inhibiting the expression of epigenetic regulators cellular differentiation. |
Potential |
|
To study the role of histone variants and other epigenetic regulators in controlling pre-mRNA splicing on brain function and spermatogenesis using mouse knockout models. |
Potential |
|
Tracking ribosome footprints to reveal the intricacy and control of translation |
Potential |
|
Translational control in cancer. |
Current |
