Projects

Project Status
Elucidate the role of testis-specific histone variant expression in the Purkinje neurons of mouse cerebellum Potential
5-methylcytosine as a transcriptome-wide epitranscriptomic mark Potential
A novel mechanism of epigenetic information transfer between different cell types Potential
A novel mechanism of long-term memory formation that involves testis-specific histone variant expression in the brain Potential
Characterisation of the role of H2A.B spermatogenesis during heat stress Potential
Characterization of splicing alterations in cancer Current
Defence mechanisms against Koala retroviruses Potential
Developing new avenues for the treatment of Hodgkin lymphoma and other blood cancers Potential
Evaluation of the role of testis-specific histone variant H2A.Bbd in Hodgkin lymphoma and other cancers Potential
Gene regulation through interactions between RNA, enzymes and metabolites Potential
How is H2A.B involved in Hodgkin lymphoma carcinogenesis? Potential
Identification of multi-step splicing events genome-wide Potential
Innovative methods to detect rapid translational control. Current
Investigating a role of C/T antigens in spermatogenesis and cancer Potential
Investigation of a role of H2A.B3 in piRNA biology Potential
Messenger RNA and noncoding RNA in cardiac biology Potential
New avenues for early detection of cancer in Hodgkin Lymphoma patients who are likely to relapse under current treatment Potential
Novel computational methods for long-read sequencing Current
Rapid translation-based stress responses to environmental changes. Current
To determine the role of histone variants, and other important epigenetic regulators, in regulating gene transcription and splicing by performing high-resolution nucleosome mapping and structure experiments. Potential
To elucidate the role of the epigenome, including the histone variant H2A.Z, in regulating the 3-dimensional architecture of the genome by inhibiting the expression of epigenetic regulators cellular differentiation Potential
To study the role of histone variants and other epigenetic regulators in controlling pre-mRNA splicing on brain function and spermatogenesis using mouse knockout models. Potential
Tracking ribosome footprints to reveal the intricacy and control of translation Potential
Translational control in cancer. Current