Acute Peripheral airways Damage (Exposure to chlorine gas)

Kagawa Medical University;   Drs: Isao Sato, Kazue takahashi, Yoshihoro Nishiyama, Masatada Tanabe

Case history:  32 year old male had noted a sensation of shortness of breath and perioral numbness for the past two months.   He has a history of exposure to an antifungal agent for the preceding several days immediately before the symptoms appeared.   Brinkman index 250.  Pulmonary function tests: VC 82.9%, RV/TLC 4% and FEV1 86.1%

Radiological Examinations

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Comments: The plain CXR shows nothing abnormal.   HRCT reveals lung regions of low absorption in the apices, but no abnormalities other wise.

Technegas planar scintigraphy

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Technegas SPECT

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Clinical Point:  Both Technegas planar and SPECT show abnormal deposition patterns more prominently than HRCT, probably suggesting  the functional disturbance of the peripheral airways due to inhalation of chlorine gas.

General Comments: Technegas planar images show an inhomogenous deposition of inhaled Technegas throughout both lungs but no hot spots were seen.  A more marked inhomgeneity in deposition patterns as well as hot spots are revealed by SPECT.

 


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