TECHNEGAS BIBLIOGRAPHY

Chronological listing as at August, 2007

* represent papers published as abstracts from international conferences


1. Burch WM, Sullivan PJ, McLaren CJ: Technegas - a new ventilation agent for lung scanning. Nucl Med Commun 7:865, 1986.

2. Sullivan PJ, Burch WM: A clinical appraisal of TECHNEGAS(r) for lung ventilation imaging. Nucl Med 25:A22, 1986.

3. Sullivan PJ, Burke WM, Burch WM, et al: A clinical comparison of Technegas and Xenon- 133 in 50 patients with suspected pulmonary embolus. Chest 94:300-304, Aug 1988.

4. Fawdry RM, Gruenewald SM: Initial experience with Technegas - a new ventilation agent. Australas Radiol 32: 232, 1988.

5. DeGeeter F, Bossuyt A, Jonckheer M: Comparison of Technegas to 81mKr as ventilation agent. Eur J Nucl Med 5:442, 1989.

6. Hilson AJW, Paiva D. Diamond PD et al: An ultra-fine 99mTc-aerosol (Technegas) for lung ventilation scintigraphy - a comparison with 81mKr. J Nucl Med 30: 744, 1989.*

7. Kropp J, Buhr W, Biersack HJ: Lung Inhalation - scintigraphy in newborns: a study with the new tracer Technegas. J Nucl Med 30: 744, 1989.*

8. Kropp J, Buhr W, Bockisch F, et al: inhalationsszintigraphie der lunge mit dem neuen ultra feinen aerosol "Technegas". Nucl Med 28: 61-68, 1989.

9. Lemb M, Oei TH, Sander U: Ventilation-perfusion lung SPECT in the diagnosis of pulmonary thromboembolism (PTE) using Technegas. Eur J Nucl Med 15:442, 1989.*

10. McAfee JG: update on radiopharmaceuticals for medical imaging. State of the Art. Radiology 171:593-601, 1989.

11. McAfee JG: What's new in radiopharmaceuticals for imaging? Syallabus on the categorical course on Nuclear Radiology in clinical decision making Sept 9-10, 1989. Publ American College of Radiology, Veston, VA USA, pp5-10, 1989.

12. Peltier P, Zair Y, Chetanneau A, et al: "Technegas" ventilation study. Eur J Nucl Med 15:442,1989.*

13. Amis TC. Crawford ABH, Davison A, Engel LA: Distribution of inhaled 99m Technetium labelled ultrafine carbon particle aerosol (Technegas) in human lungs. Eur Respir J 3: 679-685 1990.

14. Bomanji J, Solanki KK, Sobnack R, et al: Technegas (TcG) ventilation-perfusion (V/Q) studies; experience in 89 patients. Eur J Nucl Med 16:440, 1990.*

15. Crawford ABH, Davison A, Amis TC, Engel LA: Intrapulmonary distribution of 99mTechnetium labelled ultrafine carbon aerosol (Technegas) in severe airflow obstruction. Eur Respir J 3:686-692 1990.

16. Mannting F, Morgan MG, Hedenstrom-H, et al: A comparative study of Xe-133 and Tc-99m-gas for assessment of regional ventilation. Eur J Nucl Med 16:429, 1990.*

17. Rimkus DS, Ashburn WL: Lung ventilation scanning with a new carbon particle radioaerosol (Technegas). Clin Nucl Med 15: 222-226, 1990.

18. Isawa T, Teshima T, Anazawa M, et al: Technegas for inhalation lung imaging. Nucl Med Commun 12: 47-55, 1991.

19. Schuemichen C, Gehring T, Krause TH, Strauss E: Change of particle flow through stenoses by the physio-characteristics of radioaerosol. Eur J Nucl Med 16:428, 1990.*

20. Zwijnenburg A, Royed E, Donagen A, Zanin D: Experience with 99mTc - Technegas as a ventilation tracer; comparison with 81mKr-gas. Eur J Nucl Med 16:441, 1990.

21. Shields RA, Testa HJ, Herman KJ, Stretton TB: 99Tcm- Technegas for lung ventilation imaging: initial experience and comparison with Krypton-81m. Nucl Med Commun 10, (4) 1989.

22. Kawakami K, Iwamura A, Goto E, et al: Kinetics clinical application of 99mTc Technegas. Jap J Nucl Med 27: 725-733,1990.

23. Sasaki Y, Imai T, Kasuga H, et al: Clinical evaluation of 99mTc-Pseudogas (Technegas). Jap J Respir 10: 821-829, 1991.

24. Bunko H, Seto M Kuji I, et al: Lung ventilation with Technegas: clinical study of lung deposition and ventilation/perfusion. Jap J Nucl Med 28: 229- 239, 1991.

25. Inoue T, Watanabie N, Tateno H, et al: Clinical evaluation of lung scintigraphy with 99mTc-Technegas. Nippon Acta Radiol 50:1590-1600, 1990.

26. Kawakami K, Shimada T, Tominaga S, et al: Pulmonary distribution of 99m-Tc-Technegas in the lung - a comparative study with radioactive inert gases. Jap J Lung Dis 30: (10) 1781-1787, 1992.

27. Van der Wall H, Murray IPC, Moase A: A ventilatory assistance device for use with Technegas. Nucl Med Commun 13: 82-87, 1992. (see also Hoffer PB, Year Book of Nucl Med. ch4 132, 1993).

28. Murray IPC: Commentary - Clinical Experience with Technegas. Clin Nucl Med 16:247, 1991.

29. Isawa T, Teshima T, Anazawa Y, et al: Radioaerosol inhalation lung imaging using Technegas. Jap J Nucl Med 11:1273-1280, 1990.

30. James JM, Prescott MC, Leahy BC, et al: Hypoxia during Technegas inhalation. Nucl Med Commun 12: 287, 1991.*

31. James JM, Lloyd JJ, Leahy BC, et al: A comparison of 99Tcm-Technegas and 81Krm ventilation scintigraphy in known respiratory disease. Nucl Med Commun 12:287, 1991.*

32. James JM, Herman KJ, Lloyd JJ, et al: Evaluation of 99Tcm Technegas ventilation scintigraphy in the diagnosis of pulmonary embolism. Br J Radiol 64:711-719, 1991. (see also Hoffer PB, Year Book of Nucl Med. ch4 131, 1993).

33. James JM, Lloyd JJ, Leahy BC, et al: The incidence and severity of hypoxia associated with 99mTc Technegas ventilation scintigraphy and 99mTc MAA perfusion scintigraphy. Brit J Radiol. 65: 403-408, 1992. (see also Hoffer PB, Year Book of Nucl Med ch3 106-107, 1994).

34. Rojas-Burke J: High hopes for Technegas, J Nucl Med 32: 24N-30N (Newsline) November 1991.

35. Gottschalk A: review of reference #18. Year Book of Nucl Med ch4 148-150, 1991.

36. Delcourt E, Binon, J-P, Amir R: Lung Ventilation studies obtained with Kr-81m or Tc-99m Technegas in a geriatric population. Eur J Nucl Med 19:712, 1992.

37. James JM, Lloyd JJ, Leahy BC, et al: 99m Tc-Technegas and Krypton-81m ventilation scintigraphy: A comparison in known respiratory disease. Br J Radiol 65:(780), 1075-82, 1992.

38. Al-Janabi MA, Maltby P, Critchley M; A comparative study of Technegas and 81Krm ventilation in the scintigraphic diagnosis of pulmonary embolism (PE). Eur J Nucl Med 19: 712, 1992.*

39. Bomanji J, Alawadhi H, Beale A et al: Clinical outcomes of patients with suspected pulmonary embolism using 99Tcm Technegas as a ventilatory agent for lung scanning. Eur J Nucl Med 19: 713, 1992.*

40. Lemb M, Oei TH, Wenz B et al: Structure of ventilation SPECT - images in normal adults using Technegas. Eur J Nucl Med 19:713, 1992.*

41. Lemb M, Oei TH, Eifert H, Gunther B: Technegas; Particle structure and size distribution. Eur J Nucl Med 19: 715, 1992.*

42. Cook G, Clarke SEM: An evaluation of Technegas as a ventilation agent compared with Krypton-81m in the scintigraphic diagnosis of pulmonary embolism. Eur J Nucl Med 19: 770-774, 1992. (See also Year Book of Nucl Med ch3 108,1994).

43. Coates G: Isotope Lung Imaging: Current Opinion in Radiology 4:79-86,1992.

44. Peltier P, Bardies M, Chetanneau A, et al: Comparison of Technetium-99m and phytate aerosol in ventilation studies. Eur J Nucl Med 19: 349-354, 1992.

45. Burch WM: Technegas wash-in to confirm lung pathology? (Letter to editor) Eur J Nucl Med 20:359 1993.

46. Burch WM, Evidence for the long term biological distribution of Technegas particles. Nucl Med Commun 14: 559-561, 1993.

47. Isawa T et al: Technegas versus Krypton gas: the difference in the lungs in distribution pattern following inhalation. Jap J Clin Radiol 38: 139-148, 1993 (Jpn).

48. Lemb M, Oei TH, Eifert H, GŸnther B: Technegas: a study of particle structure, size and distribution. Eur J Nucl Med 20: (7) 576-579, 1993. (see ref # 44).

49. Strong JC, Agnew JE: The particle size distribution of Technegas and its influence on regional lung deposition. Nucl Med Commun 10: (6) 425-430, 1989.

50. Burch WM, Boyd MM, Crellin DE, Technegas: particle size and distribution. Eur J Nucl Med 21:365-367, 1994. (Response to ref # 48).

51. Kropp J, Overbeck B, Klumpp J, Inhalation scintigraphy with an ultra fine aerosol (Technegas) in infants with functional bronchial stenoses. Clin Nucl Med 18: 223-226, 1993.

52. Goransson M, Five years experience of pulmonary ventilation with Tc-99m Technegas. Eur J Nucl Med 20, 1013. 1993*.

53. Longostrevi GP, Migliara G, Allegra L, Pneumoscintigrafia ventilatoria con tracciante pseudogassoso aspetti metodologici ed applicazioni cliniche. Ital J Chest Dis 42:117-124, 1988.

54. Mackey DWJ, Burch WM, Dance IG et al. The observation of Fullerenes in a Technegas lung ventilation unit. Nucl Med Commun 15: 430-434, 1994.

55. Kransnow AZ, Isitman AT, Collier BD et al. Diagnostic applications of radioaerosols. Nuclear Medicine Annual, 1993. Ed. Freeman LM, Publ. Raven, New York USA. pp 134-137, 1993.

56. Lloyd JJ, Taylor CJ, James JM, Lawson RS, Shields RA, Testa HJ. Texture analysis of Technegas lung ventilation images. Med Biol Eng & Comp. 33:52-57, 1995.

57. Lloyd JJ, Anderson P, James JM, Shields RA, Prescott MC. Contamination levels and doses to staff arising from the use of Technegas. Nucl Med Commun 15:435-440, 1994.

58. James JM, Lloyd JJ, Shields RA, Testa HJ. Inhalation technique and Technegas deposition in normal volunteers. Nucl Med Commun 14:284, 1993.*

59. Peters AM. Recent advances and future projections in clinical radionuclide imaging. Br J Radiol 63:411-429, 1990.

60. Isawa T, Teshima T, Anazawa Y, Miki M, Motomiya M. Radioaerosol Inhalation Lung Imaging Using Technegas. Jpn J Clin Radiol, pp 64-65, 1992.

61. Messian O, Sleiman C, Mal H, Andreassian B and Bok B. Quantitative Lung Scintigraphy in the follow-up of single lung transplantation. J Nucl Med 33: (5), 835, 1992.*

62. King G, Salome C, Miekle S, Woolcock A, Pilot study of single photon emission computerised tomographic imaging (SPECT) of ventilation at residual volume in asthmatics suggests large airway closure. Aust NZ J Med 24: (4), 437, 1994*.

63. Mackie A, Hart GC, Ibbett DA, Whitehead RJS. Airborne radioactive contamination following aerosol ventilation studies. Nucl Med Commun 15:161-167, 1994.

64. Bellomo R, Low R, Pianko S, et al. The 1 month outcome of patients with a low probability Technegas ventilation/perfusion lung scan. Nucl Med Commun 15:505-510, 1994.

65. Lloyd JJ, James JM, Shields RA, Testa HJ. The influence of inhalation technique on Technegas particle deposition and image appearance in normal volunteers. Eur J Nucl Med 21:394-398, 1994.

66. Cormick W, Farlow D, Gruenewald S, Antico V. Ventilation perfusion (V/Q) scan and its impact on patient management. ANZ J Med 22:722, 1992.*

67. Kumar V. Interference by 99m - Tc (Technegas) on Co-57 dependant schillings test and vitamin-B12 assays during ventilation lung scan procedure. ANZ J Med 22:724, 1992.*

68. Goransson M. Pulmonary Ventilation with Tc-99m Technegas Compared with Tc-99m DTPA Aerosol. Eur J. Nucl Med 21:(10) - suppl;S29, 1994.*

69. Gruenewald SM, Farlow D. Radioactive Contamination to Staff and Equipment from Technegas Lung Ventilation Studies. Eur J. Nucl Med 21:(10) - suppl;S66, 1994.*

70. Giga A, Benie DN, Collins L, Gruenewald SM, & Farlow D, Radioactive contamination to staff and equipment from Technegas lung ventilation studies. Eur J Nucl Med, 21(10), S66, 1994.
71. King GG, Salome CM, Meikle SM, Woolcock AJ. Studies of Lung Ventilation in Normals and Asthmatics Using SPECT and Technegas. Eur J Nucl Med 21:(10) - suppl;S87, 1994.*
72. Miki M. Isawa T, Teshima T, et al. Comparison of Intrapulmonary Distribution of three different-sized aerosols, Technegas and Krypton Gas Following Inhalation. Eur J Nucl Med 21:(10) - suppl;S87, 1994.*
73. Zanco P, Bortolotti L, Borsato N, et al. Technegas Scan in Preoperative Evaluation of Lung Neoplasm. Eur J Nucl Med 21:(10) - suppl;S241, 1994.*
74. Kotzerke J, Strumpf A, Schafers HJ, Hundeshagen H. Technegas Investigation of Alveolar Permeability after single and double lung transplantation. Eur J Nucl Med 21:(10) - suppl; S241, 1994.*

75. Sasaki Y, Imai T, Ohishi H, et al. Use of Tc-99m Technegas SPECT in evaluating of regional pulmonary function in patients with interstitial lung disease. Eur J Nucl Med 21:(10) - suppl;S241, 1994.*

76. Isawa T, Teshima T, Anazawa Y., Technegas Versus Krypton-81m Gas as an Inhalation Agent. Comparison of Pulmonary Distribution at Total Lung Capacity. Clin Nucl Med 19:1085-1090, 1994.

77. Bernard EJ, Nour R, Butler SP, Quinn RJ. Incidence of pulmonary embolism in single segmental mismatch on lung scanning. J Nucl Med 35:1928-1931, 1994.

78. Watanabe N, Inoue T, Tomioka S et al. Discordant findings between Krypton-81m gas and Tc-99m labeled ultrafine aerosol lung ventilation SPECT in two patients with Idiopathic Pulmonary Fibrosis. Clin Nucl Med 20:315-317, 1995.

79. Uchiyama M, Mori Y, Shimada T, Kawakami K. Physiological characteristics of Tc-99m gas in non-embolic lung diseases. In comparison with Kr-81m, Xe-133 and Tc-99m aerosol. J Nucl Med 36:35P, 1995.

80. Martel AL, Tindale WB. A Comparative study of the effect of Tc-99m Technegas and Tc-99m DTPA aerosol on image appearance and lung scan reporting. Eur J. Nucl Med 21 (8) 731, 1994.*

81. Lepailleur A, PŽrault C, Loboguerrero A, et al. Interest of Parametric subtraction images in lung scan for pulmonary embolism diagnosis. Eur J. Nucl Med 21 (8) 835, 1994.*

82. Fanti S, Compagnona G, Marengo M, et al. Comparison of quantitative perfusion and Technegas ventilation scans in patients with pulmonary carcinoma. Eur J. Nucl Med 21 (8) 837, 1994.*

83. Richter K, PŸchner K, Tatsch K, Hahn K. Consecutive Ventilation and Perfusion Scintigraphy of the lung with a triple head camera. Eur J Nucl Med 22:942, 1995*.

84. Lowe VJ, Sostman HD. "Nuclear Medicine" (ed. Murray IPC & Ell PJ. Publ. Churchill Livingstone). Chapter 4 p.33, 1995.
85. Satoh K, Tanabe M, Nakano S, et al. Comp-arision of 99m Tc-Technegas Scintigraphy and High Resolution CT in Pulmonary Emphysema. Jap J Nucl Med 32:(5), 487-494, 1995 (Jpn).

86. James J.M., Testa H.J., The use of 99m Tcm - Technegas in the investigation of patients with pulmonary thromboembolism. Nucl Med Commun 16, 802-810, 1995.

87. Nozaki T, Muraoka H, Hara T, Suzuki T, Production of fine aerosols labelled with various radionuclides by sublimation from a graphite boat, and their properties and tracer use. Appl Radiat and Isot 46:3, 157-165, 1995.

88. Isawa, T, Pulmonary Nuclear Medicine (in Japanese) ISBN 4-87398-056-9 pp 71-84, 1995.

89. Scalzetti EM, Gagne GM. The Transition from Technegas to Pertechnegas. J Nucl Med 36:268--269, 1995.

90. Lloyd JJ, Shields RA, Taylor CJ, et al. Technegas & Pertechnegas particle size distribution. Eur J Nucl Med 22:(5);473-476, 1995.

91. Jackson P, Baker RJ, McCullough DG et al. A study of Technegas employing x-ray photoelectron spectroscopy, scanning transmission electron microscopy and wet chemical methods. Nucl Med Commun 17: 504-513; 1996.

92. Nakano S, Satoh K, Talcohashi K, et al. Comparison between High-Resolution Computed Tomography and 99m Tc-Technegas SPECT Pulmonary Emphysema. Jp J. Chest Dis 34:5 511-519, 1996.

93. Burch WM, Browitt RJ. The Transition from Technegas to Pertechnegas (letter in response to ref. # 89 ) J Nucl Med 37 (11), 1917-1918, 1996.

94. Tabuchi K, Narabayashi R, Matsui R, et al. Quantitative Study of Tc-99m Technegas ventilation scintigraphy in comparison with Krypton-81m gas. Ann Nucl Med 10 : (suppl), S130, 1996*.

95. Sasaki Y, Imai T, Ohishi H, et al: Estimation of regional pulmonary function in patients with interstitial lung disease using Tc-99m Technegas SPECT. Ann Nucl Med 10 : (suppl), S130, 1996*.

96. Ooshita T, Ookouchi A, Hirase K, et al. Development of an assist unit for Technegas inhalation. Ann Nucl Med 10 : (suppl), S129, 1996*.

97. Satoh, K, Takahashi K, Nishiyama Y, et al. Comparison of Tc-99m Technegas SPECT with Xe-133 dynamic SPECT in pulmonary emphysema. Ann Nucl Med 10: (suppl), S70, 1996*.

98. Burch WM, Buffinton GA Browitt RD, et al. The Technegas fulleroid particle as a nano-colloid suspension for bone marrow imaging. Ann Nucl Med 10 : (suppl), S72, 1996*.

99. Isawa T, Lee B-T, Hiraga K. High-resolution electron microscopy of Technegas and Pertechnegas. Nucl Med Commun 17: 147-152; 1996.

100. Lloyd JJ, Lawson RS, Shields RA. High-resolution electron microscopy of Technegas and Pertechnegas (letter + reply) Nucl Med Commun 17: 822-823; 1996.

101. King GG, Eberl S, Salome CM, et al. Airway closure measured by a Technegas bolus and SPECT. Am J Resp Crit Care Med 155: (2); 682-688, 1997.

102. King GG, Eberl S, Salome CM et al. Differences in airway closure between normals and asthmatics measured by SPECT and Technegas. Am J Resp Crit Care Med 158: (6); 1900-1906, 1998.

103. Beckett.M, Thakran DS., Agnew JE., et al. An audit of the usefulness of ventilation/perfusion scintigraphy in patients over 75 years. Nucl Med Commun 17: 997, 1996*.

104. Komatani A., Akutstu T., Yamaguchi K., et al. Contamination levels to room air arising from the use of 99mTc-gas and prevention from the contamination. (Japanese). Jap J Nucl Med. 33(4):443-5, 1996.

105. Kawakami K. Use of radioisotopes to study the function and morphology of the lung. (Review), (Japanese). Jap J Thor Dis. 32 Supp:223-30, 1994.

106. Kawakami K. New trends of pulmonary nuclear medicine. (Review), (Japanese). Jap J Nucl Med. 31(11):1385-90, 1994.

107. Satoh K, Tanabe M, Nakano S, et al. Comparison of 99mTc-technegas scintigraphy and high resolution CT in pulmonary emphysema. (Japanese). Jap J Nucl Med. 32(5):487-94, 1995.

108. Imaeda T, Kanematsu M, Asada S, et al. Prediction of pulmonary function after resection of primary lung cancer. Utility of inhalation-perfusion SPECT imaging. Clin Nucl Med. 20(9):792-9, 1995.

109. Zhang X, Hirano H, Yamamoto K, et al. Technegas ventilation SPECT for evaluating silicosis in comparison with computed tomography. Ann Nucl Med 10(2):165-70, 1996.

110. Coleman RE, Whackers FJTh, Peppen JA, et al. Diagnostic Nuclear Medicine. 3rd Ed. Vol1 Publ. Williams & Wilkins. P593; 1996.

111. Senden TJ, Moock KH, Fitzgerald J, et al. The physical and chemical nature of Technegas. J Nucl Med 38 (8): 1327-1333, 1997.

112. Eberl S, King GG, Meikle SR. Measurement of lung ventilation below closing volume with simultaneous emission/transmission SPECT J Nucl Med 38 (6):296, 1997.

113. Satoh K, Tanabe M, Takahashi K, et al. Assessment of Technetium-99m Technegas scintigraphy for ventilatory impairment in pulmonary emphysema: comparison of planar and SPECT images, Ann Nucl Med 11 (2):109-113, 1997.

114. Howarth DM, Thomas PA, Allen LW, Lan L, An outcome study of patients referred for ventilation and perfusion lung scintigraphy for the diagnosis of pulmonary embolus. Eur J Nucl Med 24 (8): 1997.

115. Kropp J, Andreeff L, Oehme S, et al. Diagnosis of pulmonary embolism using V/Q scintigraphy and gated SPECT. Eur J Nucl Med 24 (8): 1997.

116. Basoglu T, Erkan L, Canbaz F, et al. Transient reverse ventilation-perfusion mismatch in acute pulmonary nitrofurantoin reaction. Ann Nucl Med 11(3): 271-274, 1997.

117. Fisher KJ, Endohedral metallofullerenes - a need for a higher yield synthesis. Chimica Oggi/Chemistry Today 15: 14-17, 1997.

118. King GG, Eberl S, Salome CM, et al. Airway closure measured by a Technegas bolus and SPECT. Am J Respir Crit Care Med 155: 682-688, 1997.

119. Satoh K, Takahashi K, Sasaki M, et al. Comparison of Tc-99m Technegas with Xe-133 dynamic SPECT in pulmonary emphysema. Annal Nucl Med 11 (3): 201-206, 1997.

120. Burch WM, McLaren CJ, Croft EM et al. Pressure assisted Technegas ventilation imaging of comatose patients. Jpn J Nucl Med 34 (8): 738, 1997*.

121. Satoh K, Takahashi K, Kobayashi T et al. 99mTc-Technegas scintigraphy in panlobular emphysema. Jpn J Nucl Med 34 (8): 738, 1997*.

122. Christiansen F, Diagnostic maging of acute pulmonary embolism. Acta radiologica 38, sippl 410, pp7 - 33, 1997.

123. Hauck R.W, Ršmer W, Schulz C, Lembeck RM, Schšnig A & Schwaiger M, Ventilation perfusion scintigraphy and lung function testing to assess metal stent efficacy. J Nucl Med, 38(10), October: 1584-1589. 1997.

124. Corbus HF, Seitz JP, Larson RK, Stobbe BE, Wooten W, Sayne JW, Chavez RD & Unguez CE, Diagnostic usefulness of lung SPECT in pulmonary thromboembolism: an outcome study. Nucl. Med Commun., 18,: 897-906. 1997.(not about Technegas but makes the point of using SPECT for V/Q )

125. Rose MR, Prescott MC, Lloyd JJ, Mountford PJ Radioactivity in breast milk following the administration of 99mTc MAA from different manufacturers, with and without prior administration of Technegas. Eur J Nucl Med 24(1):89-90; 1997.

126. Komatani A, Hasegawa N, Yamaguchi K, Manaka Y, Takahashi K [Improvement of a filter and the effect on the TECHNEGAS leakage].Kaku Igaku 34(6):385-388; 1997. (Jap)

127. Salvatori M. Advances in pulmonary nuclear medicine. Rays, 22 (1): 51-72, 1997.

128. Bonnin F, Hadjikostova H, Jebrak G, et al. Complementarity of lung scintigraphy and d-dimer test in pulmonary embolism. Eur J Nucl Med 24 (4):444-447, 1997.

129. Andreef M, Oehme L., Kropp J, et al. The usage of gated SPECT in lung scintigraphy-phantom studies and clinical results. Eur J Nucl Med 25 (1), 1998.

130. Lemb M. Lungenembolie: LЧt sich das PIOPED-Resultat durch Vent/Perf SPECT unter Verwendung von Technegas verbussern? Nuklearmedizin: A29/V102, 1998.

131. Maisey M., Clarke SEM. An Atlas of Clinical Nuclear Medicine. 2nd Ed. Chapt. 7; pp521-576. ISBN 0-8151-3341-3 Publ. Mosby 1997.

132. Bernier DR, Christian PE, Langan JK. "Nuclear Medicine Technology and Techniques" 4th Ed. pp316-317 ISBN 0-8151-1991-7 Publ. Mosby 1997.

133. Freeman Leonard M, Scintigraphic diagnosis of pulmonary embolism. Nuc. Med Annual 1997

134. Eberl S, Uren R, Bautovich G, Saunders C, Dugal T, Forster J. SPECT ventilation/perfusion lung scanning in the diagnosis of pulmonary embolism. J Nucl Med 39: (5 suppl.); 191p, 1998*

135. Cook P, Bedford B, Bell A, Lang P, Leiper C, Prouse A. Evaluation of a positive ventilation delivery system (PVDS) in administering Technegas to the noncompliant patient. Eur J Nucl Med 25: (8) 1189, 1998*.

136. Harbert JC, Eckleman WC, Newmann RD. Nuclear Medicine diagnosis and therapy. Publ. Theime: p562-563; 1996.

137. Wilson MA. Textbook of Nuclear Medicine. Publ.Lippincott/Raven p100; 1997

138. Maisey MM, Britton KE, Coya PD. Clinical nuclear Medicine 3rd Ed. Publ. Chapman&Hall Medical: p221-222; 1998

139. Hincken RE, Bowles MA, Dilakai GL et al. Nuclear Medicine Vol. 2 Publ. Mosby: p1371-1379; 1996

140. Sasaki Y, Imai T, Shinkai T, et al. Estimation of regional lung function in interstitial pulmonary disease using 99mTc-Technegas and 99mTc- macroaggregated albumin single-photon emission tomography. Eur J Nucl Med 25: 1623-1629; 1998.

141. Basoglu T, Canbaz F, Bernay I, Danaci M Bilateral pulmonary artery aneurysms in a patient with Behcet syndrome: evaluation with radionuclide angiography and V/Q lung scanning. Clin Nucl Med 23(11):735-738;1998.

142. Mettler FA, Guiberteau MJ. Essentials of Nuclear Medicine Imaging. Publ. Saunders. p195; 1998.

143. Britton KE. Highlights lecture of the European Association of Nuclear Medicine and the World Federation of Nuclear Medicine and Biology congress, Berlin 1998. "Where next and how"? Eur J Nucl Med 25: (12) (Technegas reference p.1682); 1998.

144. Nair CH, Browitt RJ, Shats EA, et al. ThromboTrace a new diagnostic agent with high specificity to bind fibrin in vivo. Eur J Nucl Med 25: (8); 879, 1998*

145. Lemb M, Oei TH, Wenz B, Haubold-Reuter B. Pulmonary Thromboembolism: how to get rid of the intermediate scan by V/P-SPECT using Technegas. Eur J Nucl Med 25: (8); 879, 1998*

146. Jackson P A Mackey D and Van der Wall, H. Physical and Chemical Nature of Technegas. J Nucl Med 39:(9); 1646-1647, (letter) 1998

147. Senden TJ, Moock KH, Fitzgerald JDF, et al. Physical and Chemical Nature of Technegas (letter in reply) J Nucl Med 39:(9); 1647-1649, 1998

148. Barghouth G, Yersin B, Doenz F, Bischof-Delaloye A. Clinical pre-test probability and lung scan in the diagnostic approach of pulmonary embolism: 2 year patient outcome. Eur J Nucl Med 25: (8); 880, 1998*

149. DeBondt P, Carp L, Tiellieu I, et al. Ventilation scintigraphy in the diagnosis of bronchopleural fistula after pneumonectomy. Eur J Nucl Med 25: (8); 1093, 1998*

150. Imai T, Sasaki Y, Shinkai T, et al. Clinical evaluation of 99m-Tc-Technegas SPECT in thoracoscopic lung volume reduction surgery in patients with pulmonary emphysema. Eur J Nucl Med 25: (8); 1095, 1998*

151. Nagao M, Murase K, Yasuhara Y, et al. Quantitative analysis of pulmonary emphysema: three dimensional fractal analysis of Technegas SPECT images. Eur J Nucl Med 25: (8); 1097, 1998*

152. Larson G, Nikadon I, Svensson E, et al. 99m-Tc contamination of Technologists during Technegas ventilation. Eur J Nucl Med 25: (8); 1190, 1998*

153. Kwiatek MA, Jones KL, Burch WM, et al: Use of Technegas as a radiopharmaceutical for the measurement of gastric emptying. Eur J Nucl Med 26: 903-906; 1999

154. Lin P, Chu J, Kiat H, et al. SPET versus planar ventilation/perfusion (V/Q) lung scans in the diagnosis of pulmonary emboli. Nucl Med Commun 20: (4), 391; 1999*

155. Howarth DM, Lan L, Thomas PA, Allen LW. 99mTc Technegas ventilation and perfusion lung scintigraphy for the diagnosis of pulmonary embolus. J Nucl Med 40: 579-584; 1999.

156. Fujita J, Takahashi K, Satoh K, Okada H, Momoi A, Yamadori I, Ohkawa M, Takahara J, Tanabe M. Tc-99m Technegas scintigraphy to evaluate the lung ventilation in patients with oral corticosteroid-dependent bronchial asthma. Ann Nucl Med13(4):247-251; 1999.

157. Collignon M-A, Exploraitons radioisotopiques et maladie thromboembolique pulmonaire. Rev Mal Respir 16: 894-906; 1999

158. Bahk YIW, Kim EE, Isawa T. Nuclear Imaging of the Chest; Publ. Springer. pp17,32,34,85. 1998.

159. Wenger M, Moncayo R., Zaknun J et al. 3D Imaging and volume mathematics versus common static imaging in combined inhalation/perfusion lung scintigraphy. Eur J Nucl Med 25(1), 1998.

160. Scalzetti EM, Gagne GM, Scott JH, Majetich SA. Electron microscopic observations on Technegas and Pertechnegas. Aerosol Sci & Technol 28: 523, 1998.

161. Vanbilloen HP, Bauwens J, Mortelmans L, et al. Reduction of contamination risks during clinical studies with Technegas. Eur J Nucl Med 26: 1349-1352; 1999.

162. Mouratidis B, Lising J, Nogrady S, Hurwitz, M. Increased Pertechnegas lung clearance in interstitial lung disease. Clin Nucl Med 4(2):105-108; 1999

163. Tucker B, Jenkins S, Cheong D, Robinson P. Effect of unilateral breathing exercises on regional lung ventilation. Nucl Med Commun. 20(9):815-821. 1999.

164. Lopez MA, Minano JA, Terron JA, Bullejos JA, Guerrero R, Arroyo T Calculation of airborne radioactivity in a Technegas lung ventilation unit. Nucl Med Commun 20(12):1141-1145; 1999.

165. Fong W, Macfarlane D, Walker D. Non-embolic causes for large mis-matched perfusion defects. Nucl Med Commun 20(4):365; 1999.*

166. Kollaros N, Vezirgianni S, Saranti E, et al., Lung scintigraphy with 99mTc-Technegas. Greek J Nucl Med 2: 41-45; 1999.

167. Mitani M, Satoh K, Takahashi K, Kobayashi T, Yamamoto Y, Nishiyama Y, Ohkawa M, Katoh T, Hosokawa N [Quantitative study of 99mTc-Technegas SPECT for ventilatory impairment in pulmonary emphysema]. Nippon Igaku Hoshasen Gakkai Zasshi. 59(6):261-4. (Jap.) 1999.

168. Burch W. Reduction of contamination risks during clinical studies with Technegas (response to ref# 152.) Eur J Nucl Med. 27(2); 237-238. 2000

169. Bargouth G, Yersin B, Boubaker A, et al. Combination of clinical and V/Q scan assessment for the diagnosis of pulmonary embolism: a 2 year outcome prospective study. Eur J Nucl Med 27: 1280-1285; 2000.

170. Wong DC, Haindl W The use of Technegas in the detection of a bronchopleural fistula. Clin Nucl Med. 25(7):548-9; 2000.

171. Nagao M, Murase K, Ichiki T, et al. Quantitative analysis of Technegas SPECT: evaluation of regional severity of emphysema. J Nucl Med 41(4):590-5; 2000.

172. Satoh K [99mTc-Technegas].Nippon Igaku Hoshasen Gakkai Zasshi 60(5):243-248; 2000(Jap).

173. Wenger M, Donnemiller E, Bacher-Stier C, et al. Improved pulmonary diagnosis by pixel based 3D-Volume mathematics in combined Inhalation/Perfusion Lung SPET. Eur J Nucl Med 27(8 ):899;2000*.

174. Leiper C, Bui C, Saunders C, Dixon H, et al. A Feasibility Study of a new Positive Pressure Delivery System using Technegas for ventilation studies that are technically inadequate or non-diagnostic. Eur J Nucl Med 27(8):1203; 2000.*

175. Garin E, Devillers A, Girault S, et al. Interpretative difficulties of Ventilation/Perfusion Lung Scan in association with Interstitial Infiltration in the diagnosis of Acute Pulmonary Embolism: About a False Positive Result. Eur J Nucl Med 27(8): 1203; 2000.*

176. Hartmann IJC, Hagen PJ, Stokkel MPM, et al. Can Technegas replace Krypton Gas as a Ventilation Agent. Eur J Nucl Med 27(8):1204; 2000.*

177. Votion DM, Coghe J, Lekeux PM. Value of Technegas for ventilation Imaging in a Calf. Eur J Nucl Med 27(8):1206; 2000.*

178. Coghe J, Votion DM, Lekeux PA. Comparison between radioacitive aerosol, Technegas and Krypton for ventilation imaging in healthy calves. Vet J 160: 25-32; 2000.

179. Johansson A, Vikgren J, Moonen M, et al. Structure and Ventilation Distribution in Pulmonary Emphysema. Eur J Nucl Med 27(8):1207;2000.*

180. Hagen PJ, van Striijen, MJ, Kieft GJ, et al. Pulmonary Embolism, Availability of diagnostic facilities in the Netherlands for patients with suspected pulmonary embolism. ANTELOPE Study Group. Advances in New Technologies Evaluating the Localisation of Pulmonary Embolism. Neth J Med 57(4):142-9; 2000.

181. Hartmann IJC, Hagen PJ, Stokkel MPM, et al. Technegas Versus 81Kr Ventilation-perfusion scintigraphy: a comparati ve study in patients with suspected acute pulmonary embolism. J Nucl Med 42: 393-400; 2001.

182. Xu JH, Moonen M, Johansson A, Blake, B. Dynamics of "Technegas" deposited in the Lung. Nucl Med Commun 22(4): 383-387; 2001.

183. Rizzo-Padoin N, Farina A, Le Pen C, et al. A Comparison of radiopharmaceutical agents used for the diagnosis of Pulmonary Embolism. Nucl Med Commun 22(4):375-381; 2001.

184. Pellegrino R, Biggi A, Papaleo A, et al. Regional expiratory flow limitation studied with Technegas in asthma. J Appl Physiol 91: (5); 2190-2198, 2001.

185. "Minerva", Faulty Technegas generator diagnoses Thyrotoxicosis. BMJ 323: 1376, 2001.

186. Votion DM, Coghe JD, Lekeux PM. Comparison of deposition images obtained by use of an ultrafine 99m-Technetium-labelled carbon dry aerosol with ventilation images obtained by use of 81m-Krypton gas for pulmonary dysfunction in calves. Am J Vet Res : 2001.

187. Wescott J, Dykes F, Brown F, et al. Lung SPECT does not reduce the rate of reporting intermediate probability of Pulmonary Embolism. J ANZSNM Mar:2001.*

188. McDonald WBG, Van der Schaff AA, Patrikeos A, Thomson R. Ventilation-Perfusion Scintigraphy vs. Helical CT angiography in suspected Pulmonary Embolism. J ANZSNM Mar:2001.*

189. Carolan M, McLean R, Bui C, et al. Post Revised PIOPED: A Trial of new clinical and scintigraphic algorithms. J ANZSNM Mar:2001.*

190. Wai-Chan Ling, McLean R, Carolan M. What happens after a Lung Scan? Management and outcome of patients in Regional Hospital. J ANZSNM Mar:2001.*

191. Reinhartz P, Schirp U, Zimmy M, et al. Optimizing ventilation-perfusion lung scintigraphy: parting with planar imaging. Nuklearmedizin 40:38-43; 2001.

192. Hartmann IJ, Prins MH, Buller HR, Banga JD. Acute pulmonary embolism: impact of selection bias in prospective diagnostic studies. Antelope study group. Advance in new technology evaluating the localization of Pulmonary Embolism. Thromb Heamostat 85(4):604-608; 2001.

193. Narita H, Ooshita T, Itoh T, et al. Development of the chromatography analysis of liquid trapping 99mTc-Technegas using Jikei impinger. Kaku Igaku. 38(3):211-218; 2001.

194. Dei S, Machida K, Honda N, et al. Fractal analysis for ventilation/perfusion ratio map in differentiating lung diseases. J Nucl Med 42:(5); 191P, 2001*.

195. Dumarey N, Lahoutte T, Dierickx LO, et al. Improvement of inter-observer agreement with the help of sagittal and transverse slices in lung V/Q SPET in the diagnosis of pulmonary embolism. J Nucl Med 42:(5); 345P, 2001*.

196. Xu J, Moonen M, Johansson Å, et al. quantitative analysis of inhomogeneity in ventilation SPET. Eur J Nucl Med 28: (12); 1795-1800, 2001.

197. Castellani M, Vanoli M, Cali G, et al. Ventilation-perfusion lung scan for the detection of pulmonary involvement in Takayasu's arteritis. Eur J Nucl Med 28(12);1801-1805, 2001.

198. Lemb M, Pohlabeln H, Pulmonary thromboembolism: a retrospective study on the examination of 991 patients by ventilation/perfusion SPECT using Technegas. Nuklearmedizin40: 179-186; 2001.

199. Orellana PB, Arriagada DM, MenesesLQ, et al. Parámetros clinicos y radiológicos de pacientes con tromboembolismo pulmonary diagnosticado a través de cintigrafias de ventilación/perfusion de alta probabilidad. http://www.alasbimnjournal.cl/revistas/14/orellana.html

200. Nemmar A, Hoet PHM, Vanquickenborne B, et al. Passage of inhaled particles into the blood circulation in humans. Circulation 105: 411-414; 2002.

202. Cantalupi D, Masaneo I, Poti C. Our experience to keep V/Q scan a mandatory tool if: (a) safe to operate and (b) reported for PE with pre/post test probability and for other respiratory problems to internists. Eur J Nucl Med 29: s9; 2002*.

203. Ito H, Pitcairn GR, Hirst PH, et al. an in vivo study to asses the suitability of Technegas as a SPECT imaging agent for pulmonary drug formulations. Respir Drug Devel VIII 2: 439-442, 2002.

204. Pitcairn GR, James J, Joyson A, et al. Technecoat: a novel method for radiolabelling dry powder formulations in radionuclide imaging studies. Respir Drug Devel VIII 2: 553-556, 2002.

205. Sanchez-Crespo A, Petersson J, Nyren S, et al. A novel quantitative dual isotope method for simultaneous ventilation and perfusion lung SPET. Eur J Nucl Med 29: 863-875, 2002.

206. Suga K, Yashuko K, Zaki M, et al. assessment of rregional lung functional impairment with co-registered respiratory-gated ventilation/perfusion SPET-CT images: initial experiences. Eur J Nucl Med Mol Imaging 31: 240-249, 2004.

207. Kropp J, Prescher Y, Beuthein-Baumann B, et al. Experience of V/P tomography. Eur J Nucl Med Mol Imaging 31 (suppl. # 2): S213, 2004*

208. Weinmann P, Tofighi M, Rebillard O, et al. Ventilation/perfusion SPECT in patients with non diagnostic planar lung scintigraphy and suspicion of pulmonary embolism. Eur J Nucl Med Mol Imaging 31 (suppl. # 2): S254, 2004*.

209. Härkönen R, Parvianen S, Mäki M, et al. Detection of pulmonary emboli by V/Q planar scintigraphy, V/Q SPET and helical CT. Eur J Nucl Med Mol Imaging 31 (suppl. # 2): S254, 2004*.

210. Ferran N, Martin-Comin J, Serra J, et al. Diagnosis of pulmonary thromboembolism(PT): comparative study spiral CT vs ventilation-perfusion pulmonary scintigraphy. Eur J Nucl Med Mol Imaging 31 (suppl. # 2): S254, 2004*.

211. Suga K, Kawakami Y, Zaki M, et al. Clinical utility of co-registered respiratory-gated 99m Tc-Technegas/MAA SPECT-CT images in the assessment of regional lung functional impairment in patients with lung cancer. Eur J Nucl Med Mol Imaging 31: 1280-1290, 2004.

212. Reinartz P, Wildberger J, Schaefer W, et al. Tomographic imaging in the diagnosis of pulmonary embolism: a comparison between V/Q lung scintigraphy in SPECT technique and multislice spiral CT. J Nucl Med 45: 1501-1508, 2004.


213. Johansson MJ, Wiklund A, et al. Positive end-expiratory pressure affects regional redistribution of ventilation differently in prone and supine sheep. Crit Care Med 32:2039-44,2004.


214. Petersson J et al. Physiological evaluation of a new quantitative SPECT method measuring regional ventilation and perfusion J Appl Physiol 96:1127-36, 2004.


215. McLean RG et al. Comparison of new clinical and scintigraphic algorithms for the diagnosis of PE.Br J Radiol77: 372-376;2004.


216. Olsson C-G, Bajc M, et al. Value of ventilation/perfusion SPECT detecting extensive pulmonary embolism in a patient with pneumonia. Thromb Haemost93: 993-994, 2005.


217. Johansson Å, Moonen M, et al. Detection of chronic rejection by quantitative ventilation scintigrams in lung-transplanted patients: a pilot study. Clin Physiol Funct imaging 25: 183-187, 2005.


218. Jonsson B, Bajc M. diagnostics of pulmonary embolism with emphasis on ventilation/perfusion scintigraphy and dead-space analysis. J Organ Dysfunction (preview article) pp1-7; 2006.


219. Mills NL, Amin N, Robinson SD et al. Do inhaled carbon nanoparticles translocate directly into the circulation in humans? Am J Respir Crit Care Med 173: 426-431; 2006.

220. Reinartz P, Kaiser H-J, Wildberger JE. SPECT imaging in the diagnosis of pulmonary embolism: automated detection of match and mismatch defects by means of image processing techniques. J Nucl Med (in press) 2006.


221. Möller W, Felton K, Seitz J, et al. A generator for the production of ultrafine carbonaceous particles for deposition and clearance studies in the
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222. Magnant J, Vecellio L, de Monte M et al. Comparative analysis of different scintigraphic approaches to assess pulmonary ventilation. J Aerosol Med 2006; 19:148-159.

223. Howarth DM, Booker JA, Voutnis DD. Diagnosis of pulmonary embolus using ventilation/perfusion lung scintigraphy: more than 0.5 segment of ventilation/perfusion mismatch is sufficient. Internal Med J 2006; 36:281-288.

224. Ue H, Haneishi H, Iwanaga H, Suga K. Nonlinear motion correction of respiratory-gated lung SPECT images. IEEE Trans Med Imaging 2006;25:486-95.


225. Harris B, Bailey D, Roach P, et al. Objective analysis of the V/Q relationship in pulmonary embolism diagnosis using SPECT scintigraphy. Eu J Nucl Med Mol Imaging 33: suppl 2; pS170, 2006*


226. Salaun PY, Le Gal G, Couturier O, et al. Does the association of low-probability ventilation-perfusion scintigraphy and of a low clinical risk safely rule out pulmonary embolism (PE) in suspected patients? Eu J Nucl Med Mol Imaging 33: suppl 2; pS170, 2006*

227. Birchall JD, Blackwell K, Ganatra RH, et al. Does an abnormal CXR preclude a VQ scan? Eu J Nucl Med Mol Imaging 33: suppl 2; pS170, 2006*

228. Mulholland NJR, Mistry R, Buxton-Thomas M. Is V/Q scanning redundant in the diagnosis of PE?: experience using an algorithm involving CTPA, V/Q and D-Dimer in a teaching hospital. Eu J Nucl Med Mol Imaging 33: suppl 2; pS171, 2006*

229. Bajc M, Olsson C, Olsson B, et al. holistic interpretation of ventilation/perfusion SPECT from 4696 studies. Eu J Nucl Med Mol Imaging 33: suppl 2; pS171, 2006*

230. Yap KSK, Turkalow A, Kalff V, et al. A prospective reassessment of the Wells’ score in identifying pulmonary embolism (PE) in the context of current diagnostic imaging recommendations. Eu J Nucl Med Mol Imaging 33: suppl 2; pS171, 2006*

231. Rodriguez-Alfonso B, Rodriguez-Rey C, Sanchez-Sanchez R, et al. Pulmonary embolism: correlation between ventilation-perfusion scintigraphy and CT findings. Eu J Nucl Med Mol Imaging 33: suppl 2; pS366, 2006*

232. Härkönen RA, Parviainen S, Mäki MT, et al. Detection of peripheral pulmonary embolism by ventilation/perfusion SPECT in cases where helical CT was non diagnostic. Poster presented at WFNMB Seoul, Korea, October 2006*

233. Yokoe K, Satoh K, Yamamoto Y, et al. Usefulness of 99mTc-Technegas and 133Xe dynamic SPECT in ventilatory impairment.
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234. Magnant J, Vecellio L, de Monte M et al. Comparative analysis of different scintigraphic approaches to assess pulmonary ventilation.
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235. Weibert P, Sanchez-Crespo A, Falk R, et al. No significant translocation of inhaled 35-nm carbon particles to the circulation in humans. Inhal Toxicol 18(10): 741-7 2006

236. Harris B, Bailey D, Miles S, et al. Objective analysis of tomographic ventilation-perfusion scintigraphy in pulmonary embolism. Am J Respir Crit Care Med 175: 1173-1180; 2007

237. Reinartz P, Nowak B, Wildberger J et al. PIOPED II in the diagnosis of pulmonary embolism: evolution or stagnation? J Nucl Med 47: (Supplement 1); 20P 2006.

238. Leveillee F, LeBlanc M, turcotte E. Prospective evaluation of the negative predictive value of V/Q SPECT using Tc-99m-Technegas.
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