Projects & Supervisors

Project name Group Supervisors
Characterization of H2A.Lap1 KO mice spermatogenesis following heat stress or gamma irradiation. The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Elucidate the role of testis-specific histone variant expression in the Purkinje neurons of mouse cerebellum The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Gene regulation in human neutrophils from patients with systemic vasculitis The Cook Group - Translational Research Professor Matthew Cook
5-methylcytosine as an epitranscriptomic mark The Preiss Group - RNA Biology Professor Thomas Preiss
5-methylcytosine as an epitranscriptomic mark The Preiss Group - RNA Biology Dr Ulrike Schumann
670nm Red Light as a treatment for Retinopathy of Prematurity (Phase 1 Clinical Trial) The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
A longitudinal study of depression, anxiety, substance use and cognitive change: PATH Through Life The Easteal Group - Genome Diversity & Health Professor Simon Easteal
A new paradigm for the control of cellular function: the dynamic reshaping of the epigenome by histone variants The Tremethick Group - Chromatin and transcriptional regulation during development Professor David Tremethick
A novel mechanism of long-term memory formation that involves testis-specific histone variant expression in the brain The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
A novel role for the pol I transcription factor UBF in the regulation of expression of histone gene clusters and cellular DNA damage responses The Hannan Group - Cancer Therapeutics Dr Kate Hannan
Abnormal brain development in a rat model of Hirschsprung's disease The Song Group Dr Zan-Min Song
Application of Bayesian modelling of high-throughput genomic data to obtain robust and interpretable estimates of model parameters The Hannan Group - Cancer Therapeutics Dr Maurits Evers
B cell responses to malaria The Cockburn Group - Malaria Immunology Associate Professor Ian Cockburn
Biological validation of machine learning models for HBV infection and disease
Brain tumour models The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
Calcium imaging of presynaptic terminals The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Cancer Stem Cell Models The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
CFS/ME Pathology in silico
Characterising mutation
Characterising the plasma cell compartment in Waldenstrom Macroglobulinaemia The Hannan Group - Cancer Therapeutics Dr Dipti Talaulikar
Chromatin and RNA surveillance The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
Circuit mapping in the piriform cortex using optogenetics The Bekkers Group - Olfaction Professor John Bekkers
Consequences of impaired neuronal activity during development in a mouse model of autism The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Defining the biological role, regulation and signalling mechanism for IL-5 The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Determining synaptic properties in small networks of neurons The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Developing new avenues for the treatment of Hodgkin lymphoma and other blood cancers The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Development of a molecular tool for personalised cancer treatment – a synthetic biology approach The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
Development of CRISPR/Cas9 genome editing technology The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Development of novel drugs for the treatment of sepsis The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Developmental expression and role of a receptor involved in schizophrenia The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Disease heterogeneity in NHL The Hannan Group - Cancer Therapeutics Dr Dipti Talaulikar
Early signs of impaired neuronal activity in a mouse model of striatum-related pathology The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Embryonic development: How does disrupted Nodal signalling cause brain defects? The Arkell Group - Early Mammalian Development Associate Professor Ruth Arkell
Embryonic development: How does elevated Wnt signalling cause heart defects? The Arkell Group - Early Mammalian Development Associate Professor Ruth Arkell
Epilepsy and olfaction The Bekkers Group - Olfaction Professor John Bekkers
Establish a robust and reproducible high-throughput data analysis workflow using snakemake The Hannan Group - Cancer Therapeutics Dr Maurits Evers
Evaluate B cell immunity to HIV vaccines The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluate the quality of HIV-specific mucosal and systemic immunity following prime-boost vaccination The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluate the role of IL-4/IL-13 at the vaccination site in the context of antigen presenting cells and innate lymphocytic cells The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluate vaccine route specific immunity in relation to IL-4 and IL-13 The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluation of the role of testis-specific histone variant H2A.Bbd in Hodgkin lymphoma and other cancers The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Evolution of behavioural, personality and cognitive diversity in humans The Easteal Group - Genome Diversity & Health Professor Simon Easteal
Evolution of vertebrate photoreceptors and the vertebrate retina The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
Functional Ca imaging of odour responses in the piriform cortex The Bekkers Group - Olfaction Professor John Bekkers
Gene regulation through interactions between RNA, enzymes and metabolites The Preiss Group - RNA Biology Professor Thomas Preiss
Gene regulation through interactions between RNA, enzymes and metabolites The Preiss Group - RNA Biology Dr Nikolay Shirokikh
Genetic and cellular basis of human immune deficiency The Cook Group - Translational Research Professor Matthew Cook
Genetic identification of the host response to malaria The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Genetics and Machine Learning
Genetics and Machine Learning
Genetics of the host response to multi-drug resistant bacteria or “superbugs” The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Genome editing as a novel way to study the interactions between the host and pathogens The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Genomic catastrophe and retrotransposons reactivation in breast cancer tissues
Glial modulation of neuronal activity The Billups Group - Synaptic Mechanisms Dr Brian Billups
Glutamate recycling at presynaptic terminals The Billups Group - Synaptic Mechanisms Dr Brian Billups
Harnessing the immune response against cancer The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Higher order image statistics and image texture The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
Host red enzymes as targets for host-directed antimalarial therapy The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
Associate Professor Brendan McMorran
Host red enzymes as targets for host-directed antimalarial therapy The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
Professor Simon Foote
How IL-5, IL-3 and GM-CSF regulate blood cell growth and function The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Identification and analysis of platelet polymorphisms associated with malaria susceptibility The McMorran Group - Genetics and Infectious Diseases
The Foote Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Associate Professor Brendan McMorran
Identify biomarkers to measure vaccine-specific mucosal immunity The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Identifying the causes of germline mutation The Easteal Group - Genome Diversity & Health Professor Simon Easteal
Identifying the genetic signatures of acquired resistance to Pol I transcription inhibitors in cancer The Hannan Group - Cancer Therapeutics Dr Maurits Evers
Infection and Immunity in silico: Hepatitis B virus
Inferring function
Investigating how pertubations in ribosome biogenesis inhibit cellular growth The Hannan Group - Cancer Therapeutics Dr Amee George
Investigating the role of heparan sulfate and heparanase in tumour metastasis, angiogenesis and inflammation The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Investigating the role of platelets in tumour metastasis The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Investigation of the functions of the mammalian homologues of Drosophila genes The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Leukemia Models The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
Mapping the functional evolution of three prion protein family genes The Gready Group - Computational & Conceptual Biology Professor Jill Gready
Mathematical models of non-random features of synaptic transmission The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Mechanisms regulating IL-5 gene expression in T lymphocytes The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Messenger RNA and noncoding RNA in cardiac biology The Preiss Group - RNA Biology Professor Thomas Preiss
Messenger RNA and noncoding RNA in cardiac biology The Preiss Group - RNA Biology Dr Ulrike Schumann
Migration, effector function and transcriptional regulation of Th17 The Bruestle Group - Inflammatory T Cell Responses Dr Anne Bruestle
Modelling human primary immune deficiences in mice The Enders Group - Immunization Genomics Dr Anselm Enders
Modelling of presynaptic calcium dynamics during synaptic depression The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Modelling of short-term synaptic plasticity at cortical synapses The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Molecular Control of the Interneuron Integration and Synapse Formation The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Molecular, cellular, and functional differences between rod and cone photoreceptors The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
Monogenic human immune deficiency disease The Cook Group - Translational Research Professor Matthew Cook
Multifocal pupillographic objective perimetry The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
Multifocal visual evoked potentials The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
Mutations in ribosome biogenesis and MDS The Hannan Group - Cancer Therapeutics Dr Dipti Talaulikar
NET and histone-mediated damage of insulin-producing islet beta cells The Simeonovic Group - Diabetes/Transplantation Immunology Associate Professor Charmaine Simeonovic
Neural circuits for odour-processing in the rodent piriform cortex 'in vivo' The Bekkers Group - Olfaction Professor John Bekkers
Neuronal and behavioural correlates of sensory adaptation The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Neuronal substrate of choice The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Neutrophils and their extracellular traps in MS pathology The Bruestle Group - Inflammatory T Cell Responses
The Parish Group - Cancer & Vascular Biology
Dr Anne Bruestle
Neutrophils and their extracellular traps in MS pathology The Bruestle Group - Inflammatory T Cell Responses
The Parish Group - Cancer & Vascular Biology
Professor Chris Parish
New avenues for early detection of cancer in Hodgkin Lymphoma patients who are likely to relapse under current treatment The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
New technology to design mutants of the photosynthetic enzyme Rubisco The Gready Group - Computational & Conceptual Biology Professor Jill Gready
NF-kB signalling in human inflammatory disease The Cook Group - Translational Research Professor Matthew Cook
Optimising the dose of 670nm light therapy for treatment of retinal degenerations The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
Phospholipid transport and B cell development The Enders Group - Immunization Genomics Dr Anselm Enders
Platelet-based autoimmune diseases The Gardiner Group - Mechanisms of Thrombosis and Cancer Associate Professor Elizabeth Gardiner
Platelet-tumour cell interactions and cancer-related thrombosis The Gardiner Group - Mechanisms of Thrombosis and Cancer Associate Professor Elizabeth Gardiner
Platelets as an intravascular link in neurological diseases (eg Alzheimer’s Disease) The Gardiner Group - Mechanisms of Thrombosis and Cancer Associate Professor Elizabeth Gardiner
Presymptomatic Signatures of Interneuron Dysfunction in Mice Models of Striatum-Related Pathologies The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Projection of three-dimensional light fields for neurophotonics The Daria Group - Neurophotonics Dr Vincent Daria
Recovery from intense bleaching exposures: human photoreceptors, retinal bipolar cells, and the overall visual system The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
Regulation of chromatin remodeling of the rRNA genes in mouse embryonic stem cells The Hannan Group - Cancer Therapeutics Dr Nadine Hein
Response recovery and adaptation in vertebrate photoreceptors The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
RNA polymerase I inhibitors as therapeuitics for cancer: analysis of p53 -dependent and – independent cell cycle checkpoints The Hannan Group - Cancer Therapeutics Professor Ross Hannan
RNA polymerase I inhibitors as therapeuitics for cancer: Testing combination therapies for heamtologic malignancies The Hannan Group - Cancer Therapeutics Professor Ross Hannan
Role of a transcription factor involved in cell identity and function The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Role of miRNA in retinal degeneration The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
Sensory coding mechanisms in rat somatosensory system The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Sensory integration in the whisker pathway The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Simulation of “in-silico” genomic high-throughput sequencing data to assess and benchmark results from different computational tools, and to guide parameter optimisation The Hannan Group - Cancer Therapeutics Dr Maurits Evers
Stem cell transplantation in treating cerebellar cell loss in Hirschsprung’s disease The Song Group Dr Zan-Min Song
Studying histidine-rich glycoprotein (HRG) The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Studying the interaction between genes and environment in Indigenous Kidney Disease The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Professor Simon Foote
Studying the interaction between genes and environment in Indigenous Kidney Disease The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Associate Professor Brendan McMorran
Studying the interaction between genes and environment in Indigenous Kidney Disease The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Dr Gaétan Burgio
T cell responses to malaria The Cockburn Group - Malaria Immunology Associate Professor Ian Cockburn
Technology and methodology development
Test novel mucosal vaccine adjuvants to enhance mucosal B and T cell immunity against mucosal pathogens The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Testing compounds that may have pro- or anti-angiogenic activities The Parish Group - Cancer & Vascular Biology Professor Chris Parish
The contribution of platelets and/or neutrophils to diabetes development The Simeonovic Group - Diabetes/Transplantation Immunology Associate Professor Charmaine Simeonovic
The development of low-dose IL-2 therapy for inflammatory and autoimmune diseases The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The development of superagonist monoclonal antibodies to human IL-21 in immunotherapy for infection and cancer The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The differentiation and function of follicular cytotoxic T (Tfc) cells in infection and cancer The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The regulation of follicular helper T (Tfh) cells in vaccination and autoimmune diseases The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The role of chromatin in the repression of pervasive transcription The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
The role of epigenetics factors in genomic instability
The role of heparanase in Type 1 diabetes The Simeonovic Group - Diabetes/Transplantation Immunology Associate Professor Charmaine Simeonovic
The role of IL-5 in allergic lung disease The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
The role of oxidative stress in the progression of retinal degenerations The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
The role of pervasive transcription in genomic instability and how it contributes to cancer development The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
The role of platelets in the protection against malarial infection The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
Associate Professor Brendan McMorran
The spatial frequency doubling illusion The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
The special role of histone variants in regulating the inheritance and three-dimensional organisation of the epigenome The Tremethick Group - Chromatin and transcriptional regulation during development Professor David Tremethick
The use of miRNA as potential therapeutic targets in diseases causing retinal degenerations The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
Tissue specific factors of Th17cell mediated autoimmunity The Bruestle Group - Inflammatory T Cell Responses Dr Anne Bruestle
Tracking factor footprints to reveal the intricacy and control of translation initiation The Preiss Group - RNA Biology Professor Thomas Preiss
Tracking factor footprints to reveal the intricacy and control of translation initiation The Preiss Group - RNA Biology Dr Nikolay Shirokikh
Transcriptional control of the MYC oncogene The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
Treatment and prevention of cancer by targeting cancer cell metabolism with dichloroacetate. The Blackburn Group - Cancer Metabolism & Genetics Associate Professor Anneke Blackburn
Uncovering new epigenetic-based regulatory mechanisms of gene expression: novel links between histone variants, RNA function and disease The Tremethick Group - Chromatin and transcriptional regulation during development Professor David Tremethick
Understand the IL-4/ IL-13 molecular mechanisms governing the induction of high avidity T and B cell immunity The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Understanding B cell development - The role of SPPL2A on B cell survival The Enders Group - Immunization Genomics Dr Anselm Enders
Understanding how host genes affect anti-viral immunity The Tscharke Group - Viruses and Immunity Professor David Tscharke
Understandingthe function of a receptor in interneuron identity and plasticity The Dehorter Group - Neuronal Development Dr Nathalie Dehorter
Use live animal imaging technologies to assess vaccine safety and uptake The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Viruses and Immunity The Tscharke Group - Viruses and Immunity Professor David Tscharke
Why do live pathogens make better vaccines? The Cockburn Group - Malaria Immunology Associate Professor Ian Cockburn

Updated:  24 July 2017/Responsible Officer:  Director, JCSMR/Page Contact:  Web Manager