Projects & Supervisors

Project name Group Supervisors
Characterization of H2A.Lap1 KO mice spermatogenesis following heat stress or gamma irradiation. The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Elucidate the role of testis-specific histone variant expression in the Purkinje neurons of mouse cerebellum The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Gene regulation in human neutrophils from patients with systemic vasculitis The Cook Group - Translational Research Professor Matthew Cook
5-methylcytosine as an epitranscriptomic mark The Preiss Group - RNA Biology Professor Thomas Preiss
670nm Red Light as a treatment for Retinopathy of Prematurity (Phase 1 Clinical Trial) The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
A longitudinal study of depression, anxiety, substance use and cognitive change: PATH Through Life The Easteal Group - Genome Diversity & Health Professor Simon Easteal
A new paradigm for the control of cellular function: the dynamic reshaping of the epigenome by histone variants The Tremethick Group - Chromatin and transcriptional regulation during development Professor David Tremethick
A novel mechanism of long-term memory formation that involves testis-specific histone variant expression in the brain The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
A novel role for the pol I transcription factor UBF in the regulation of expression of histone gene clusters and cellular DNA damage responses The Hannan Group - Cancer Therapeutics Dr Kate Hannan
Abnormal brain development in a rat model of Hirschsprung's disease The Song Group Dr Zan-Min Song
Application of Bayesian modelling of high-throughput genomic data to obtain robust and interpretable estimates of model parameters The Hannan Group - Cancer Therapeutics Dr Maurits Evers
B cell responses to malaria The Cockburn Group - Malaria Immunology Associate Professor Ian Cockburn
Biological validation of machine learning models for HBV infection and disease Associate Professor Brett Lidbury
Bionic touch The Stuart Group - Neuronal Signalling Dr Jason Potas
Brain tumour models The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
Calcium imaging of presynaptic terminals The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Cancer Stem Cell Models The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
CFS/ME Pathology in silico Associate Professor Brett Lidbury
Characterising mutation
Characterising the plasma cell compartment in Waldenstrom Macroglobulinaemia The Hannan Group - Cancer Therapeutics Dr Dipti Talaulikar
Chromatin and RNA surveillance The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
Circuit mapping in the piriform cortex using optogenetics The Bekkers Group - Olfaction Professor John Bekkers
Defining the biological role, regulation and signalling mechanism for IL-5 The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Determining synaptic properties in small networks of neurons The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Developing new avenues for the treatment of Hodgkin lymphoma and other blood cancers The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Development of a molecular tool for personalised cancer treatment – a synthetic biology approach The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
Development of CRISPR/Cas9 genome editing technology The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Development of novel drugs for the treatment of sepsis The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Disease heterogeneity in NHL The Hannan Group - Cancer Therapeutics Dr Dipti Talaulikar
Epilepsy and olfaction The Bekkers Group - Olfaction Professor John Bekkers
Establish a robust and reproducible high-throughput data analysis workflow using snakemake The Hannan Group - Cancer Therapeutics Dr Maurits Evers
Evaluate B cell immunity to HIV vaccines The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluate the quality of HIV-specific mucosal and systemic immunity following prime-boost vaccination The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluate the role of IL-4/IL-13 at the vaccination site in the context of antigen presenting cells and innate lymphocytic cells The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluate vaccine route specific immunity in relation to IL-4 and IL-13 The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Evaluation of the role of testis-specific histone variant H2A.Bbd in Hodgkin lymphoma and other cancers The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
Evolution of behavioural, personality and cognitive diversity in humans The Easteal Group - Genome Diversity & Health Professor Simon Easteal
Evolution of vertebrate photoreceptors and the vertebrate retina The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
Functional Ca imaging of odour responses in the piriform cortex The Bekkers Group - Olfaction Professor John Bekkers
Gene regulation through interactions between RNA, enzymes and metabolites The Preiss Group - RNA Biology Professor Thomas Preiss
Genetic and cellular basis of human immune deficiency The Cook Group - Translational Research Professor Matthew Cook
Genetic identification of the host response to malaria The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Genetics and Machine Learning The Arcos-Burgos Group Associate Professor Brett Lidbury
Genetics and Machine Learning The Arcos-Burgos Group Associate Professor Mauricio Arcos-Burgos
Genetics of the host response to multi-drug resistant bacteria or “superbugs” The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Genome editing as a novel way to study the interactions between the host and pathogens The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions Dr Gaétan Burgio
Genomic catastrophe and retrotransposons reactivation in breast cancer tissues
Glial modulation of neuronal activity The Billups Group - Synaptic Mechanisms Dr Brian Billups
Glutamate recycling at presynaptic terminals The Billups Group - Synaptic Mechanisms Dr Brian Billups
Harnessing the immune response against cancer The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Higher order image statistics and image texture The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
Host red enzymes as targets for host-directed antimalarial therapy The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
Associate Professor Brendan McMorran
Host red enzymes as targets for host-directed antimalarial therapy The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
Professor Simon Foote
How IL-5, IL-3 and GM-CSF regulate blood cell growth and function The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Identification and analysis of platelet polymorphisms associated with malaria susceptibility The McMorran Group - Genetics and Infectious Diseases
The Foote Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Associate Professor Brendan McMorran
Identify biomarkers to measure vaccine-specific mucosal immunity The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Identifying the causes of germline mutation The Easteal Group - Genome Diversity & Health Professor Simon Easteal
Identifying the genetic signatures of acquired resistance to Pol I transcription inhibitors in cancer The Hannan Group - Cancer Therapeutics Dr Maurits Evers
Infection and Immunity in silico: Hepatitis B virus Associate Professor Brett Lidbury
Inferring function
Investigating how pertubations in ribosome biogenesis inhibit cellular growth The Hannan Group - Cancer Therapeutics Dr Amee George
Investigating the role of heparan sulfate and heparanase in tumour metastasis, angiogenesis and inflammation The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Investigating the role of platelets in tumour metastasis The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Investigation of the functions of the mammalian homologues of Drosophila genes The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Leukemia Models The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
Light therapy for neural regeneration The Stuart Group - Neuronal Signalling Dr Jason Potas
Mapping the functional evolution of three prion protein family genes The Gready Group - Computational & Conceptual Biology Professor Jill Gready
Mathematical models of non-random features of synaptic transmission The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Mechanisms regulating IL-5 gene expression in T lymphocytes The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
Messenger RNA and noncoding RNA in cardiac biology The Preiss Group - RNA Biology Professor Thomas Preiss
Migration, effector function and transcriptional regulation of Th17 The Bruestle Group - Inflammatory T Cell Responses Dr Anne Bruestle
Modelling human primary immune deficiences in mice The Enders Group - Immunization Genomics Dr Anselm Enders
Modelling of presynaptic calcium dynamics during synaptic depression The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Modelling of short-term synaptic plasticity at cortical synapses The Stricker Group - Neuronal Networks Associate Professor Christian Stricker
Molecular Control of the Interneuron Integration and Synapse Formation The Dehorter Group Dr Nathalie Dehorter
Molecular, cellular, and functional differences between rod and cone photoreceptors The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
Monogenic human immune deficiency disease The Cook Group - Translational Research Professor Matthew Cook
Multifocal pupillographic objective perimetry The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
Multifocal visual evoked potentials The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
Mutations in ribosome biogenesis and MDS The Hannan Group - Cancer Therapeutics Dr Dipti Talaulikar
Neural circuits for odour-processing in the rodent piriform cortex 'in vivo' The Bekkers Group - Olfaction Professor John Bekkers
Neuronal and behavioural correlates of sensory adaptation The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Neuronal substrate of choice The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Neutrophils and their extracellular traps in MS pathology The Bruestle Group - Inflammatory T Cell Responses
The Parish Group - Cancer & Vascular Biology
Dr Anne Bruestle
Neutrophils and their extracellular traps in MS pathology The Bruestle Group - Inflammatory T Cell Responses
The Parish Group - Cancer & Vascular Biology
Professor Chris Parish
New avenues for early detection of cancer in Hodgkin Lymphoma patients who are likely to relapse under current treatment The Tremethick Group - Chromatin and transcriptional regulation during development Dr Tanya Soboleva
New technology to design mutants of the photosynthetic enzyme Rubisco The Gready Group - Computational & Conceptual Biology Professor Jill Gready
NF-kB signalling in human inflammatory disease The Cook Group - Translational Research Professor Matthew Cook
Optimising the dose of 670nm light therapy for treatment of retinal degenerations The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
Phospholipid transport and B cell development The Enders Group - Immunization Genomics Dr Anselm Enders
Platelet-based autoimmune diseases The Gardiner Group - Mechanisms of Thrombosis and Cancer Associate Professor Elizabeth Gardiner
Platelet-tumour cell interactions and cancer-related thrombosis The Gardiner Group - Mechanisms of Thrombosis and Cancer Associate Professor Elizabeth Gardiner
Platelets as an intravascular link in neurological diseases (eg Alzheimer’s Disease) The Gardiner Group - Mechanisms of Thrombosis and Cancer Associate Professor Elizabeth Gardiner
Presymptomatic Signatures of Interneuron Dysfunction in Mice Models of Striatum-Related Pathologies The Dehorter Group Dr Nathalie Dehorter
Projection of three-dimensional light fields for neurophotonics The Daria Group - Neurophotonics Dr Vincent Daria
Recovery from intense bleaching exposures: human photoreceptors, retinal bipolar cells, and the overall visual system The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
Regulation of chromatin remodeling of the rRNA genes in mouse embryonic stem cells The Hannan Group - Cancer Therapeutics Dr Nadine Hein
Response recovery and adaptation in vertebrate photoreceptors The Lamb Group - Visual Neuroscience Emeritus Professor Trevor Lamb
RNA polymerase I inhibitors as therapeuitics for cancer: analysis of p53 -dependent and – independent cell cycle checkpoints The Hannan Group - Cancer Therapeutics Professor Ross Hannan
RNA polymerase I inhibitors as therapeuitics for cancer: Testing combination therapies for heamtologic malignancies The Hannan Group - Cancer Therapeutics Professor Ross Hannan
Role of miRNA in retinal degeneration The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
Sensory coding mechanisms in rat somatosensory system The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Sensory integration in the whisker pathway The Arabzadeh Group - Neural Coding Associate Professor Ehsan Arabzadeh
Sensory processing in the spinal cord The Stuart Group - Neuronal Signalling Dr Jason Potas
Simulation of “in-silico” genomic high-throughput sequencing data to assess and benchmark results from different computational tools, and to guide parameter optimisation The Hannan Group - Cancer Therapeutics Dr Maurits Evers
Stem cell transplantation in treating cerebellar cell loss in Hirschsprung’s disease The Song Group Dr Zan-Min Song
Studying histidine-rich glycoprotein (HRG) The Parish Group - Cancer & Vascular Biology Professor Chris Parish
Studying the interaction between genes and environment in Indigenous Kidney Disease The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Professor Simon Foote
Studying the interaction between genes and environment in Indigenous Kidney Disease The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Associate Professor Brendan McMorran
Studying the interaction between genes and environment in Indigenous Kidney Disease The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
The Burgio Group - Genome Editing and Genetics of Host-Pathogens Interactions
Dr Gaétan Burgio
T cell responses to malaria The Cockburn Group - Malaria Immunology Associate Professor Ian Cockburn
Technology and methodology development
Test novel mucosal vaccine adjuvants to enhance mucosal B and T cell immunity against mucosal pathogens The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Testing compounds that may have pro- or anti-angiogenic activities The Parish Group - Cancer & Vascular Biology Professor Chris Parish
The development of low-dose IL-2 therapy for inflammatory and autoimmune diseases The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The development of superagonist monoclonal antibodies to human IL-21 in immunotherapy for infection and cancer The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The differentiation and function of follicular cytotoxic T (Tfc) cells in infection and cancer The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The regulation of follicular helper T (Tfh) cells in vaccination and autoimmune diseases The Yu Group - T-cell Immune Mechanism, Monitoring and Modulation (TIM3) Associate Professor Di Yu
The role of chromatin in the repression of pervasive transcription The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
The role of epigenetics factors in genomic instability
The role of IL-5 in allergic lung disease The Young Group - Cytokine Molecular Biology & Signalling Professor Ian Young
The role of oxidative stress in the progression of retinal degenerations The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
The role of pervasive transcription in genomic instability and how it contributes to cancer development The Fischer Group - Epigenetics and Genomic Stability Associate Professor Tamás Fischer
The role of platelets in the protection against malarial infection The Foote Group - Genetics and Infectious Diseases
The McMorran Group - Genetics and Infectious Diseases
Associate Professor Brendan McMorran
The spatial frequency doubling illusion The Maddess Group - Diagnostics for Eye Diseases Professor Ted Maddess
The special role of histone variants in regulating the inheritance and three-dimensional organisation of the epigenome The Tremethick Group - Chromatin and transcriptional regulation during development Professor David Tremethick
The use of biomaterials for nervous repair The Stuart Group - Neuronal Signalling Dr Jason Potas
The use of miRNA as potential therapeutic targets in diseases causing retinal degenerations The Provis Group - Gene expression in the human macula
The Valter Group - Retinal Cell Damage and Repair
Dr Riccardo Natoli
Tissue specific factors of Th17cell mediated autoimmunity The Bruestle Group - Inflammatory T Cell Responses Dr Anne Bruestle
Tracking factor footprints to reveal the intricacy and control of translation initiation The Preiss Group - RNA Biology Professor Thomas Preiss
Transcriptional control of the MYC oncogene The Hannan Group - Cancer Therapeutics Dr Leonie Quinn
Treatment and prevention of cancer by targeting cancer cell metabolism with dichloroacetate. The Blackburn Group - Cancer Metabolism & Genetics Associate Professor Anneke Blackburn
Uncovering new epigenetic-based regulatory mechanisms of gene expression: novel links between histone variants, RNA function and disease The Tremethick Group - Chromatin and transcriptional regulation during development Professor David Tremethick
Understand the IL-4/ IL-13 molecular mechanisms governing the induction of high avidity T and B cell immunity The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Understanding B cell development - The role of SPPL2A on B cell survival The Enders Group - Immunization Genomics Dr Anselm Enders
Understanding how host genes affect anti-viral immunity The Tscharke Group - Viruses and Immunity Professor David Tscharke
Use live animal imaging technologies to assess vaccine safety and uptake The Ranasinghe Group - Molecular Mucosal Vaccine Immunology Associate Professor Charani Ranasinghe
Use of L1 retrotransposon as a novel breast cancer biomarker
Viruses and Immunity The Tscharke Group - Viruses and Immunity Professor David Tscharke
Why do live pathogens make better vaccines? The Cockburn Group - Malaria Immunology Associate Professor Ian Cockburn

Updated:  26 February 2017/Responsible Officer:  Director, JCSMR/Page Contact:  Web Manager