Genome editing as a novel way to study the interactions between the host and pathogens

Novel precision genetic technologies such as CRISPR/Cas9 genome editing technology offer novel avenues to a better understanding of the interactions between the host and the pathogens. Using CRISPR/Cas9 we are able to precisely and efficiently target any modification of the mouse and the pathogens genomes. We are able to precisely modify the mouse genome by creating knockout or a specific single nucleotide change to enable the study of the function of the gene of interest. We also modify the genome of the pathogens to study this fascinating interplay between the host and the pathogens.

Updated:  27 June 2017/Responsible Officer:  Director, JCSMR/Page Contact:  Web Manager