Our group discovers molecular and cellular mechanisms and genes regulating
the immune response, either:
• to prevent autoimmunity against self antigens (eg lupus, diabetes,
rheumatoid arthritis, thyroiditis);
• to prevent uncontrolled growth of lymphoid malignancies (leukemia,
lymphoma and myeloma);
• or to promote immunity and immunological memory against viruses
and bacteria (immunization and immunological memory).
We aim to answer central questions about the mechanisms of tolerance
and immunity in B and T cells, and to create a collaborative environment
where the next generation of scientific leaders can establish independent
lines of research while drawing upon shared expertise and resources.
To achieve these aims, we develop and use state-of-the-art methods
from mouse and human molecular genetics and genomics, biochemistry
and cell biology, cell signalling, cellular immunology and clinical
immunology.
Members of our group pursue exciting research problems that break
new ground conceptually and clinically, and learn a broad range of
methods and concepts from across the fields of modern genomics and
immunology.
Immune Tolerance & Signalling
Laboratory
Leader: Professor Chris Goodnow
Cell Mediated Immunogenomics
Laboratory
Team Leader: Dr Edward Bertram
(also Head of Scientific Programs, Australian Phenomics Facility)
Ramaciotti Immunization Genomics
Laboratory
Leader: Dr Anselm Enders
Staff
Opportunities for
Students
