2009:
Cai, Y., Zhou, J. and Webb D.C. (2009) Treatment of mice with fenbendazole attenuates allergic airways inflammation and Th2 cytokine production in a model of asthma. Immunol Cell Biology July 21 Epub ahead of print

Cai, Y., R. K. Kumar, J. Zhou, P. S. Foster, and D. C. Webb. (2009) Ym1/2 promotes cytokine expression by inhibiting 12/15(S)-lipoxygenase: Identification of a novel pathway for regulating allergic inflammation. J Immunol 182:5393-5399.

2008:
Zhou, J., Wolf, C. R., Henderson, C. J., Cai, Y., Board, P. G., Foster, P. S. and Webb, D. C. (2008) Glutathione transferase P1: an endogenous inhibitor of allergic responses in a mouse model of asthma. Am J Respir Crit Care Med 178:1202.

Herbert, C., Hettiaratchi, A. Webb, D.C., Thomas, P. S., Foster, P. S. and Kumar, R. K. (2008) Suppression of cytokine expression by roflumilast and dexamethasone in a model of chronic asthma. Clin Exp Allergy 38:847-856.

2007:
Webb, D. C., Cai, Y., Matthaei, K. I. and Foster, P. S. (2007) Comparative roles of IL-4, IL-13 and IL-4R(alpha) in dendritic cell maturation and CD4+ Th2 cell function. J Immunol 48: 219-227.

Webb, D. C., Otczyk, D. C. and Cripps, A. W. (2007) Investigation of a 48kDa protein as a vaccine candidate for infection against nontypeable Haemophilus influenzae. Vaccine 25: 4012-4019.

2006:
Yang, M., Rangasamy, D., Frew, A. J., Mahalingham, S., Webb, D. C., Tremethick, D, J., Thompson, P. J., Hogan, S. P., Matthaei, K. I., Rothenberg, M. E., Cowden, W. B. and Foster, P. S. (2006) Inhibition of arginase I activity by RNA interference attenuates interleukin-13 induced airways hyperresponsiveness. J Immunol 177:5595-5603.

Kumar, R. K., Webb, D.C., Herbert, C. and Foster, P. S. (2006) Interferon-gamma as a possible target in chronic asthma. Inflamm Allergy Drug Targets 5: 253-256.

2004:
Webb, D. C., Matthaei, Ki. I., Cai, Y., McKenzie, A. N. J. and Foster, P. S. (2004) Polymorphisms in interleukin (IL)-4 receptor alpha correlate with airways hyperreactivity, eosinophilia and Ym expression in allergic IL-13-/- mice. J Immunol 172:1092-1098.

Kumar, R. K., Herbert, C., Li, L., Webb, D. C. and Foster, P. S. (2004) Effects of anti-cytokine therapy in a mouse model of chronic asthma. Am J Respir Crit Care Med 170: 1043-1048.

2003:
Foster, P. S., Webb, D. C., Yang, M., Herbert, C. and Kumar, R. K. (2003) Dissociation of the Th2 cytokine-dependent airway lesions from STAT6 signalling in experimental chronic asthma. Clin Exp Allergy 3: 688-695.

Kumar, R. K., Herbert, C., Thomas, P. S., Wollin, L., Beume, R., Yang, M., Webb, D. C. and Foster, P. S. (2003) Inhibition of inflammation and remodeling by roflumilast and dexamethasone in murine chronic asthma. J Pharm Exp Ther 307: 349-355.

Webb, D. C., Mahalingam, S., Cai, Y., Matthaei, K. I., Donaldson, D. D. and Foster, P. S. (2003) Antigen-specific production of interleukin (IL)-13 and IL-5 co-operate to mediate IL-4Ra-independent airway hyperreactivity. Eur J Immunol 33: 3377-3385.

2002:
Foster, P. S., Hogan, S. P., Yang, M., Mattes, J., Young, I. G., Matthaei, K., Kumar, R. K., Mahalingam, S. and Webb, D. C. (2002) Interleukin-5 and eosinophils as therapeutic targets for asthma. Trends in Mol Med 8: 162-167.

Mattes, J., Yang, M., Mahalingam, S., Kuer, J., Webb, D. C., Simson, L., Hogan, S. P., Koskinen, A., Dent, L., Rothenberg, M. E., Matthaei, K. I., Young, I. G. and Foster, P. S. (2002) Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J Exp Med 195: 1433-1444.

2001:
Webb, D. C., McKenzie, A. N. J., Matthaei, K. I., Rothenberg, M. E. and P. S. Foster. (2001) Distinct spatial requirements for eosinophil-induced airways hyperreactivity. Imm Cell Biol 79: 165-169 (invited special feature).

Zuegg, J., Webb, D. C., Foster, P. S. and Casarotto, M. G. (2001) A structural model of human IL-13 defines the spatial interactions with the IL-13Ra/IL-4Ra receptor. Imm Cell Biol 79: 332-339.

Harris, R. M., Webb, D. C., Howitt, S. M. and Cox, G. B. (2001) Characterization of PitA and PitB from Escherichia coli. J Bact 183: 5008-5014.

Mattes, J., Yang, M., Siqueira, A., Clark, K., MacKenzie, J., McKenzie, A. N. J., Webb, D. C., Matthaei, K. I. and Foster, P. S. (2001) Interleukin-13 induces airways hyperreactivity independently of the IL-4Ra chain in the allergic lung. J Immunol 167: 1683-1692.

Webb, D. C., McKenzie, A. N. J. and Foster, P. S. (2001) Expression of the Ym2 lectin binding protein in the allergic lung is dependent on IL-4 and IL-13 signal transduction: Identification of a novel allergy-associated protein. J Biol Chem 276: 41969-41076.

Foster, P. S., Mould, A. W., Yang, M., MacKenzie, J., Mattes, J., Hogan, S. P., Mahalingam, S., McKenzie, A. N. J., Rothenberg, M. E., Young, I. G., Matthaei, K. I. and D. C. Webb. (2001) Elemental signals regulating eosinophil accumulation in the lung.
Immun Reviews 179: 1-9.

Recent Conference Presentations:
Webb, D. C. 2008 Ym1/2 promotes Th2 cytokine production by inhibiting 12/15-lipoxygenase. Plenary at the International Congress on Cytokines in Health and Disease, Florence, Italy.

2008 D.C. Webb, P.G. Board, C.R. Wolf, C.J. Henderson, P.S. Foster, J. Zhou.
The ability of Glutathione transferase Pi to suppress eosinophilia, mucus production, remodeling and airways hyperresponsiveness correlates with inhibition of c-Jun phosphorylation and IL-5 in a mouse model of allergic airways disease. Workshop Presentation at The American Thoracic Society Meeting, Toronto Canada. Am J Respir and Crit Care Med 177:A978

Grants Held:
2003-2007 NHMRC Peter Doherty Training Fellowship (ID: 179841): $229,252
Identification and stoichiometry of downstream transcription factors of an IL-13-dependent, IL-4R?-independent receptor associated with airways hyperreactivity.

2006-2008 CIA NHMRC Project Grant (ID: 366765): $277,500
Functional analysis of the Ym2-chitinase like lectin in allergic airways disease.

2008-2010 CIA NHMRC Project Grant (ID: 471401): $419,250
The role of gluathione transferase P1 in regulating allergic airways disease.