2009
Wang J, Lee S, Teh CE, Bunting K, Ma L, Shannon
MF. The
transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress
IL-2 gene activation in T cells. Int Immunol. 2009 Mar;21(3):227-35.
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J,
Shannon MF, Goodall GJ. A
double-negative feedback loop between ZEB1-SIP1 and the microRNA-200
family regulates epithelial-mesenchymal transition.Cancer Res. 2008
Oct 1;68(19):7846-54.
2008
Brettingham-Moore, K.H., Sprod, O.R., Chen, X, Oakford,
P, Shannon, M.F. and Holloway, A.F, Determinants of
a transcriptionally competent environment at the GM-CSF promoter. Nucleic
Acids Res. 2008 May;36(8):2639-53.
2007
Bunting, K, Rao, S, Hardy, K, Woltring, D, Denyer, GS,
Wang, J, Gerondakis, S and Shannon, M.F., Genome-wide
analysis of gene expression in T cells to identify targets of the NF-kB
transcription factor c-Rel. J Immunol 2007 Jun 1;178(11):7097-109.
Shannon, M.F., Genomic aspects of host response. In
Handbook of Genomic Medicine (Eds; Willard H and Ginsburg, G) Elsevier.
In press. Jan 2007.
2006
Bunting, K., Wang, J., and Shannon, M.F.,
2006, Control of interleukin-2 gene transcription: a paradigm for inducible,
tissue-specific gene expression.In Vitamins and Hormones, Interleukins,
(eds. G. Litwack.) 74: Elsevier Academic Press INC. pp. 105-145.
Shannon, M.F., Chen, X., Brettingham-Moore,
K., and Holloway, A., 2006, Chromatin Remodelling: Distinct Molecular
Events During Differentiation and Activation of T Cells. Current Immunology
Reviews 2, 273-289.
Rao, S, Bunting, K, Sutcliffe, EL and Shannon,
M.F., (2006) Deciphering regulatory networks controlled by
the NF-kB transcription factor c-Rel in T cells. In Microarrays and
Transcription Networks, 75-89 (Eds: MF Shannon and S Rao) Landes Bioscience.
Books
Transcriptional Regulatory Networks and Microarrays. Eds
MF Shannon and S Rao. (2006) Molecular Biology Intelligence
Unit, Landes Bioscience. ISBN 1-58706-290-9.
2005
Brettingham-Moore, K.H., Rao, S., Juelich, T., Shannon,
M.F., and Holloway, A.F., (2005), GM-CSF promoter chromatin
remodelling and gene transcription display distinct signal and transcription
factor requirements. Nucleic Acids Research 33(1), 225-34.
Chen, X., Wang, J., Woltring, D., Gerondakis, S., and
Shannon, M.F., 2005, Histone Dynamics on the Interleukin-2
Gene in Response to T-Cell Activation. Molecular and Cellular Biology
25(8), 3209-3219.
Shannon, M.F., McKenzie, K.U.S., Edgley,
A., Rao, S., Peng, K., Shweta, A., Schyvens, C.G., Anderson, W.P., Wilson,
S.R., Pittelkow, Y.E., Ohms, S., and Whitworth, J.A.,( 2005), Optimizing
microarray in experimental hypertension. Kidney International 67(1),
364-370.
Wang, J., Shannon, M.F., and Young, I.G., 2005, A role
for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5
transcription in mouse Th-2 lymphocytes. International immunology 18(20),
313-323.
2004
Grumont, R., Lock, P., Mollinari, M., Shannon,
M.F., Moore, A., and Gerondakis, S., (2004) The mitogen-induced
increase in T cell size involves PKC and NFAT activation of Rel/NF-kappa
B-dependent c-myc expression. Immunity 21(1), 19-30.
2003
Shannon, MF. (2003). A nuclear address with influence.
Nature Genetics 34 (1): 4-6.
Rao S, Gerondakis S, Woltring D and Shannon MF
(2003). c-Rel is required for chromatin remodeling across the IL-2
gene promoter. Journal of Immunology 170, 3724-3731
Holloway AF, Rao S, Chen X and
Shannon MF (2003). Changes in chromatin accessibility across the
GM-CSF promoter upon T cell activation are dependent on nuclear factor
kB proteins. J Exp Med 197, 413-423.
2002
Attema JL, Reeves R, Murray V, Levichkin I, Temple MD,
Tremethick DJ, Shannon MF (2002). The human IL-2 gene promoter
can assemble a positioned nucleosome that becomes remodeled upon T
cell activation. J Immunol 169, 2466-2476.
Shannon Frances M, Rao Sudha.(2002). Of Chips
and ChIPs ( Perspectives: Transcription). Science 296, 666-668
2001
Cakouros D, Cockerill PN, Bert AG, Mital R, Roberts
DC and Shannon MF (2001) An NF-kB/Sp1 region is essential for
chromatin remodeling and correct transcription of a human granulocyte
macrophage-colony stimulating factor transgene. J Immunol. 167, 302-310
Diamond P, Shannon MF, Vadas MF and Coles LS.
(2001) Cold shock domain factors activate the granulocyte-macrophage-colony
stimulating factor promoter in stimulate jurkat T cells. J. Biol.
Chem, 276: 7943-7951.
Holloway AF, Rao S, Shannon MF (2001) Regulation
of cytokine gene transcription in the immune system. Mol Immunol 38,
567-80.
Rao S, Procko E, Shannon MF (2001) Chromatin
Remodeling, Measured by a Novel Real-Time Polymerase Chain Reaction
Assay, Across the Proximal Promoter Region of the IL-2 Gene. The Journal
of Immunology 167, 4494-4503.
Shannon MF, Himes SR and Reeves R (2001) The
role of architectural transcription factors in IL-2 dependent T cell
proliferation.in" Interleukin --2 (IL-2) transcription"
Landes Bioscience Series (Eds Umlauf S & Beverly B). pp.1-17.
Shannon MF, Coles, LS, Attema, J and Diamond,
P. (2001) The role of architectural transcription factors in cytokine
gene transcription. J Leuk. Biol. 69: 21-32.
Shannon MF and Holloway AF. (2001) Chromatin
remodeling and transcriptional regulation of cytokine gene expression
in T cells. In "Contemporary clinical neuroscience; Cytokines and Autoimmunity",
(Eds: VK Kuchroo et al) Humana Press. pp. 416
2000
Coles LS, Diamond P, Occhiodoro F, Vadas MA, Shannon MF. (2000)
An ordered array of cold shock domain repressor elements across tumor
necrosis factor-responsive elements of the granulocyte-macrophage colony-stimulating
factor promoter. J Biol Chem 275:14482-93.
Himes SR, Reeves R, Attema J, Nissen M, Li Y, Shannon
MF. (2000) The role of high-mobility group I(Y) proteins in expression
of IL-2 and T cell proliferation. J Immunol.164, 3157-68.
Himes SR, Shannon MF. (2000) Assays for transcriptional
activity based on the luciferase reporter gene. Methods Mol Biol. 130,
165-74.
Holloway AF, Occhiodoro F, Mittler G, Meisterernst M, Shannon
MF. (2000) Functional interaction between the HIV transactivator
Tat and the transcriptional coactivator PC4 in T cells. J Biol Chem
275, 668-77.
Kochetkova M, Shannon MF. (2000) Triplex-forming oligonucleotides
and their use in the analysis of gene transcription. Methods Mol Biol
130, 189-201.
1999
Himes, SR and Shannon, MF (1999) Essays for transcriptional
activity based on the luciferase reporter gene. In Methods in Molecular
Biology. Transcription Factor Protocols (Ed Tymers MJ) 14, 165-174.
Kochetkova, M and Shannon, MF (1999) DNA triplex as a tool
to regulate cytokine gene expression. In Triplex L forming Oligonucleotides
(Eds Malvey C, Harel-Bellan A and Pritchard LL) pp159-166.
Kochetkova, M and Shannon, MF (1999) Triplex
forming oligonucleotides and their use in analysis of gene transcription.
In Methods in Molecular Biology. Transcription Factor Protocols, ed
Tymers MJ 16, 189-201.
Shang C, Attema J, Cakouros, D, Cockerill PN and Shannon MF
(1999) Nuclear Factor of Activated T cells contributes to thefunction
of the CD28 response region of the GM-CSF promoter. International
Immunology, 11:1945-1956.
1998
Shannon, MF, Himes, SR and Attema, J. (1998) A role for the architectural
transcription factors HMGI(Y) in cytokine gene transcription in T cells.
Immunol and Cell Biol. 76:461-466.
Kochetkova M and Shannon MF. (1998) DNA Triplex
formation on the GM-CSF Gene proximal promoter. Nucleosides and Nucleotides
17:9-11.
Catron KM, Brickwood, JR, Shang C, Li Y, Shannon MF and Parks
TP. (1998) Cooperative binding and synergistic activation by RelA
and C/EBPb on the ICAM-1 promoter. Cell Growth and Differentation.
9:949-959.
Kochetkova M and Shannon MF. (1998) DNA triplex formation
on the granulocyte-macrophage colony-stimulating factor gene proximal
promoter Nucleos Nucleot 17, 1801-1807
Himes SR and Shannon MF. (1998) Assays for transcriptional
activity based on the luciferase reporter gene. Methods in Molecular
Biology. in press.
Kochetkova M and Shannon MF. (1998) Triplex forming oligonucleotides
and their use in analysis of gene transcription. Triple Helix forming
oligonucliotides, 12, 159-166.
Holloway AF, Occhiodoro F and Shannon MF. Functional and physical
interaction of HIV Tat and the transcriptional coactivator PC4. Submitted.
1997
Shannon MF, Cockerill PN and Coles LS. (1997) Signals
for activation of the GM-CSF promoter and enhancer in T cells. Critical
Reviews in Immunology 18:301-324.
Kochetkova M, Iversen P, Lopez AF and Shannon MF.
(1997) Inhibition of Juvenile chronic myeloid leukemic cell growth by
triplex inhibition of GM-CSF transcription. J Clin Invest 99:3000-3008
.
1996
Himes SR, Katsikeros R and Shannon, M.F. (1996) Costimulation
of cytokine gene expression in T cells by the human T leukemia/lymphotropic
virus type 1 trans activator Tax. J. Virol. 70:4001-4008.
Kochetkova, M. and Shannon, M.F. (1996) DNA triplex
formation selectively inhibits GM-CSF gene expression in human T cells.
J. Biol. Chem. 271:14438-14444.
Coles, LS, Diamond, P, Occhiodoro, F, Vadas, MA and Shannon, MF.
(1996) Cold Shock Domain proteins repress transcription from the
GM-CSF promoter. Nucleic Acids Research 24:2311-2318.
Himes SR, Coles LS, Reeves R and Shannon MF. (1996)
High-mobility-group protein I(Y) is required for function and for c-Rel
but not Rel A binding to CD28 response elements within the GM-CSF and
IL-2 promoters. Immunity 5:479-489.
Thomas RS, Tymms MJ, McKinlay, LH, Shannon MF, Seth A and Kola
I (1996) Ets1,NF-kB and AP-1 synergistically transactivate the human
GM-CSF promoter. Oncogene 14:2845-2855.
1995
Cockerill PN, Bert AG, Jenkins F, Ryan GR, Shannon MF and Vadas
MA. (1995) Human granulocyte-macrophage colony-stimulating
factor enhancer function is associated with cooperative interactions
between AP-1 and NFATp/c. Mol & Cell Biol 15:2071-2079.
Shannon MF, Himes SR and Coles LS. (1995) GM-CSF
and IL-2 share common control mechanisms in response to costimulatory
signals in T cells. J Leuk Biol 57:1-7.
Bagley CJ, Woodcock JM, Hercus TR, Shannon MF and Lopez AF.
(1995) Interaction of GM-CSF and IL-3 with the common b-chain
of their receptors. J Leuk Biol 57:739-746.
Jenkins F, Cockerill PN, Bohmann D and Shannon MF. (1995)
Multiple signals are required for function of the human granulocyte-macrophage
colony-stimulating factor gene promoter in T cells. J Immunol
155:1240-1251.
Thomas, R.S., Tymms, M.J., Seth, A., Shannon, M.F. and Kola,
I. (1995) ETS1 transactivates the human GM-CSF promoter
in Jurkat T cells stimulated with PMA and ionomycin. Oncogene
11:2135-2143.
