T: +61 2 6125 2326
F: +61 2 6125 0415
E: david.tremethick@anu.edu.au

Mail Address:
Genome Biology Program 
The John Curtin School of Medical Research 
GPO Box 334
Canberra  ACT  2601  Australia 

 

 

The fate of the eukaryotic cell at all stages of its life cycle is dependent upon the accurate readout of genes encoded by DNA. For example, the development of a single cell into multicellular organism requires precise temporal and spatial regulation of gene transcription. Consequently, certain diseases and developmental disorders are often associated with, and likely to be caused by, aberrant gene expression. It has become increasingly clear over the last decade that eukaryotic gene regulation at the level of transcription is strictly connected to the structural organisation of the genome. The basis for this structural organisation is the nucleosome. Our overall aim is to understand how chromatin structure contributes to the regulation of transcription during development.

 

Research

Publications

Staff

Opportunities for Students