Publications

2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995

2007

Abdellatif, Y., Liu, D., Gallant, E. M., Gage, P. W., Board, P. G., and Dulhunty, A. F. (2007). The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels. Cell Calcium 41(5), 429-40.

Board, P. G., and Anders, M. W. (2007). Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones. Chem Res Toxicol 20(1), 149-54.

2006

Blackburn, A.C., Matthaei, K.I., Lim, C., Taylor, M.C., Cappello, J.Y., Hayes, J.D., Anders, M.W., and Board, P.G., 2006, Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways. Molecular Pharmacology 69(2), 650-657.

Board, P.G., 2006, A class act - The discovery of the Theta class glutathione transferases. The Biochemist 28(5), 35-38.

Casarotto, M.G., Cui, Y.F., Karunasekara, Y., Harvey, P.J., Norris, N., Board, P.G., and Dulhunty, A.F., 2006, Structural and functional characterization of interactions between the dihydropyridine receptor II-III loop and the ryanodine receptor. Clinical and Experimental Pharmacology and Physiology 33(11), 1114-1117.

Fang, Y.Y., Kashkarov, U., Anders, M.W., and Board, P.G., 2006, Polymorphisms in the human glutathione transferase zeta promoter. Pharmacogenet and Genomics 16(4), 307-13.

Shield, A.J., Murray, T.P., and Board, P.G., 2006, Functional characterisation of ganglioside-induced differentiation-associated protein 1 as a glutathione transferase. Biochemical and Biophysical Research Communications 347(4), 859-866.

2005

Board, P.G., Anders, M.W., and Blackburn, A.C., (2005), Catalytic function and expression of glutathione transferase zeta. Drug Metabolism and Transport: Molecular Methods and Mechanisms. pp. 85-107.

Dulhunty, A.F., Karunasekara, Y., Curtis, S.M., Harvey, P.J., Board, P.G., and Casarotto, M.G.,(2005), The recombinant dihydropyridine receptor II-III loop and partly structured 'C' region peptides modify cardiac ryanodine receptor activity. Biochemical Journal 385, 803-813.

2004

Board PG, Taylor MC, Coggan M, Parker MW, Lantum BH and Anders MW (2004). Clarification of the role of key active site residues of glutathione transferase Zeta/maleylacetoacetate isomerase by a new spectrophotometric technique. Biochem J 374, 731-737.

Board PG, Coggan M, Watson S, Gage PW and Dulhunty AF (2004). CLIC-2 modulates cardiac ryanodine receptor Ca(2+) release channels. Int J Biochem Cell Biol 36, 1599-1612.

Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF and Pandit J (2004). Characterization of the Omega class glutathione transferases. Chem Biol Interact, 1331, 204-206.

Catanzariti A-M, Soboleva TA, Jans DA, Board PG and Baker RT (2004). An efficient system for high-level expression and easy purifiation of authentic recombinant proteins. Protein Sci, 13, 1331-1339.

Lim CEL, Matthaei KI, Blackburn AC, Davis RP, Dahlstrom JE, Koina ME, Anders MW and Board PG (2004). Animal Model: Mice Deficient in Glutathione Transferase Zeta/Maleylacetoacetate Isomerase Exhibit a Range of Pathological Changes and Elevated Expression of Alpha, Mu, and Pi Class Glutathione Transferases. Am J Pathol, 165, 679-693.

Ricci G, Turella P, De Maria F, Antonini G, Nardocci L, Board PG, Parker MW, Carbonelli MG, Frederici G and Caccuri AM (2004) Binding and Kinetic Mechanisms of the Zeta Class Glutathione Transferase. J Biol Chem 279, 33336-33342.

Robinson A, Huttley GA, Booth HS and Board PG, Modelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerases. Biochem J, 379, 541-552.

Tetlow N, Robinson A, Mantle T and Board P (2004). Polymorphism of human mu class glutathione transferases. Pharmacogenetics 14, 359-368.

Wertz IE, O’Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker, RT, Boone, DL, Ma, A, Koonin, EV and Dixit, VM, De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kB signalling. Nature 430, 694-699.

Whitbread AK, Mellick GD, Silburn PA, Couteur DGL and Board PG, (2004). Glutathione transferase Omega class plymorphisms in Parkinson disease. Neurology 62, 1910-1911.

2003

Board PG, Taylor, MC, Coggan M, Parker MW, Lantum, Hoffman B, Anders MW (2003). Clarification of the role of key active site residues of glutathione transferase Zeta/maleylacetoacetate isomerase by a new spectrophotometric technique. Biochem J 374, 731-737.

Whitbread AK, Tetlow N, Eyre HJ, Sutherland GR and Board PG (2003). Characterization of the human Omega class glutathione transferase genes and associated polymorphisms. Pharmacogenetics 13, 131-144.

2002

Anderson WB, Liebler DC, Board PG, Anders MW (2002). Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta. Chem Res Toxicol 15, 1387-1397.

Dulhunty AF, Haarmann CS, Green D, Laver DR, Board PG and Casarotto MG (2002). Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle. Progress in Biophysics and Molecular Biology 79, 45-75.

Melton JV, Ewart GD, Weir RC, Board PG, Lee E and Gage PW (2002). Alphavirus 6K proteins form ion channels. J Biol Chem. In press.

Owczarek CM, Owczarek AL, Board PG (2002) Identification and characterization of polymorphisms at the HSA alpha(1)-acid glycoprotein (ORM*) gene locus in Caucasians. Genet Mol Biol 25, 13-19.

Cromer BA, Morton CJ, Board PG and Parker MW (2002). From glutathione transferase to pore in a CLIC. European Biophysics Journal with Biophysics Letters 31, 356-364

Lantum HBM, Board PG and Andres MW (2002). Kinetics of the biotransformation of maleylacetone and chlorofluoroacetic acid by polymorphic variants of human glutathione transferase zeta (hGSTZ1-1). Chemical Research in Toxicology 15, 957-963.

Ren X, Jemth P, Board PG, Luo G, Mannervik B, Liu J, Zhang K and Shen J (2002). A semisynthetic glutathione peroxidase with high catalytic efficiency. Selenoglutathione Transferase. Chemistry & Biology 9, 789-794

Board P. (2002) Ligandin revisited: resolution of the alpha class glutathione transferase gene family. Pharmacogenetics 12, 275-6.

Coggan M, Flanagan JU, Parker MW, Vichai V, Pearson WR, Board PG (2002). Identification and characterization of GSTT3, a third murine Theta class glutathione transferase. Biochem J. 366, 323-332.

Lantum HB, Liebler DC, Board PG, Anders MW (2002) Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone.Chem Res Toxicol 15, 707-716.

Lantum HB, Baggs RB, Krenitsky DM, Board PG, Anders MW (2002) Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues. Drug Metab Dispos 30, 616-25.

2001

Anders MW, Anderson WB, Tzeng H-F, Board PG (2001) Glutathione transferase zeta: novel xenobiotic substrates and enzyme inactivation. Chemico-Biological Interactions 133, 211-216

Bamber DE, Board PG, Coggan M, Elder JB, Deakin M, Rajagopal R, Fawole AS, Strange RC, Fryer AA (2001) Glutathione S-transferase GSTT2 polymorphism and outcome in patients with colorectal cancer. Chemico-Biological Interactions 133, 95-97.

Blackburn AC, Coggan M, Tzeng H-F, Lantum H, Polekhina G, Marker M, Anders MW and Board PG (2001) GSTZ1d, a new allele of glutathione transferase Zeta and maleylacetoacetate isomerase. Pharmacogenetics 11, 671-678.

Board PG, Chelvanayagram G, Jermiin LS, Tetlow N, Tzeng H-F, Anders MW and Blackburn AC (2001) Identification of novel glutathione transferases and polymorphic variants by expressed sequence TAG database analysis. Drug Metabolism and Disposition 29, 544-547

Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J (2001) Characterization of the Omega class glutathione transferases. Chemico-Biological Interactions 133, 204-206

Caccuri AM, Antonini G, Board PG, Flanagan J, Parker MW, Paolesse R, Turella P, Federici G, Lo Bello M, Ricci G (2001) Evolutionary strategy for optimization of GSH binding and catalysis in Alpha, Pi, Mu and Theta glutathione transferases. Chemico-Biological Interactions 133, 161-166

Caccuri AM, Antonini G, Board PG, Flanagan J, Parker MW, Paolesse R, Turella P, Chelvanayagam G and Ricci G (2001) Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of the catalytic activity of glutathione transferases. Journal of Biological Chemistry 276, 5432-5437.

Caccuri AM, Antonini G, Board PG, Flanagan J, Parker MW, Paolesse R, Turella P, Federici G, Lo Bello M and Ricci G (2001) Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of substrate binding to the active site of glutathione transferases. Journal of Biological Chemistry 276, 5427-5431.

Chelvanayagam G, Parker MW, Board PG (2001) Fly fishing for GSTs: a unified nomenclature for mammalian and insect glutathione transferases. Chemico-Biological Interactions 133, 256-260

Coggan M, Liu D, Chelvanayagam G, Anderson WB, Anders MW, Board PG (2001). Evaluation of possible active site residues in GSTZ 1-1. Chemico-Biological Interactions 133, 185-187

Dulhunty A, Gage P, Curtis S, Chelvanayagam G, Board P (2001) The Glutathione Transferase Structural Family Includes a Nuclear Chloride Channel and a Ryanodine Receptor Calcium Release Channel Modulator. The Journal of Biological Chemistry 276, 3319-3323.

Gisi D, Maillard J, Flanagan JU, Rossjohn J, Chelveneyagam G, Board PG, Parker MW, Leisinger T and Vuilleumier S (2001) Dichloromethane mediated in vivo selection and functional characterization of rat glutathione S-transferase theta 1-1 variants. European Journal of Biochemistry 268, 1-11

Harris MJ, Kuwano M, Webb M, Board PG (2001) Identification of the apical membrane-targeting signal of the multidrug resistance-associated protein 2 (MRP2/cMOAT). J Biol Chem 276, 20876-20881.

Le Couteur DG, Davis MW, Webb M, Board PG (2001) P-glycoprotein, multidrug-resistance-associated protein and Parkinson's disease. Eur Neurol 45, 289-290.

Nuccetelli M, Evangelisti C, Capo C, Petruzzelli R, Parker MW, Board P, Caccuri AM, Federici G, Ricci G, Lo Bello M (2001) Limited proteolysis as a powerful tool for probing flexible oligopeptide portions among different classes of glutathione transferases. Chemico-Biological Interactions 133, 43-48

Parker MW, McKinstry WJ, Oakley AJ, Polekhina G, Rossjohn J, Chelvanayagam G, Board PG, Di Ilio C, Caccuri AM, Ricci G, Lo Bello M (2001) Evolution of functional diversity as observed through structural studies of glutathione transferases. Chemico-Biological Interactions 133, 8-12

Polekhina G, Board PG, Blackburn AC and Parker MW (2001) The Crystal Structure of Maleylacetoacetate Isomerase/Glutathione Transferase Zeta reveals the Molecular Basis for its Remarkable Catalytic Promiscuity. Biochemistry 40, 1567-1576

Taylor MC, Board PG, Mellick GD, Blackburn AC and Le Couteur DG (2001) Zeta class glutathione transferase polymorphisms and Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry 70, 406-425.

Tetlow NL, Blackburn AC, Chelvanayagam G and Board PG (2001) Alpha class glutathione transferase polymorphisms identified by EST database analysis. Chemico-Biological Interactions 133, 123-125

Tetlow N, Liu D and Board P (2001) Polymorphism of human Alpha class glutathione transferases. Pharmacogenetics 11, 609-617.

Whitbread AK, Coggan M, Board PG (2001) Genomic structure of human GST omega 1. Chemico-Biological Interactions 133, 331-333

Yin Z-L, Dahlstrom JE, Le Couteur DG and Board PG (2001) Immunohistochemistry of Omega Class Glutathione S-Transferase in Human Tissues. The Journal of Histochemistry & Cytochemistry 49, 983-987.

Zakharyan RA, Sampayo-Reyes A, Healy SM, Tsaprailis G, Board PG, Lieber DC and Aposhian HV (2001) Human monomethylarsonic acid (MMAV) reductase is a member of the glutathione-S-transferase superfamily. Chemical Research in Toxicology 14, 1051-1057.

2000

Blackburn AC, Tzeng H-F, Anders MW and Board PG (2000) Discovery of a functional polymorphism in human glutathione transferase Zeta by expressed sequence Tag database analysis. Pharmacogenetics 10, 49-57.

Board P, Tetlow N, Blackburn A and Chelvanayagam G (2000) Database analysis and gene discovery in pharmacogenetics. Clin Chem Lab Med 38, 863-7.

Board PG, Chelvanayagam G, Jermiin LS and Blackburn A (2000) Identification and characterization of the Zeta class of glutathione transferases. Clin. Chem. & Enzyme Commun. 8, 379-384.

Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF and Pandit J. (2000) Identification, characterization, and crystal structure of the Omega class glutathione transferases. The Journal of Biological Chemistry 275, 24798-24806.

Dulhunty A, Gage P, Curtis S, Chelvanayagam G, Board P (2000) The glytathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator. Amer Soc Biochem Molec Biol Inc, ISBN 0021-9258 pp3319-3323

Flanagan JU, Chelvanayagam G, Casarotto M, Parker MW and Board PG (2000) A Mutagenic analysis of the role of Trp-115 in the human Theta class glutathione transferase GSTT2-2 Clin Chem & Enzym Commun 8, 261-269.

Flanagan JU, King W, Parker WW, Board PG and Chelvanayagram G. (2000) Ab Initio calculations on hidden modulators of Theta class glutathione transferase activity. Proteins: Structure, Function, and Genetics 39, 235-243.

Kangsadalampai S, Yenchitsomanus P, Chelvanayagam G, Sawasdee N, Laosombat V and Board P (2000) Identification of a new mutation (Gly420Ser), distal to the active site, that leads to factor XIII deficiency. Eur J Haematol 65, 279-84.

Njalsson R, Carlsson K, Olin B, Carlsson B, Whitbread L, Polekhina G, Parker MW, Norgren S, Mannervik B, Board PG and Larsson A (2000) Kinetic properties of missense mutations in patients with glutathilone synthetase deficiency. Biochem . 349, 75-279.

Oakley AJ, Rossjohn J, McKinstry WJ, Flanagan J, Board PG, Lo Bello M, Ricci G and Parker MW (2000) Structure/function studies of PI and Theta class glutathione transferases. Clin. Chem. & Enzyme Commun 8, 231-238.

Taylor MC, Le Couteur DG, Mellick GD and Board PG (2000) Paraoxonase polymorphisms, pesticide exposure and Parkinson's disease in a Caucasian population. Journal of Neural Transmission 107, 979-983.

Tzeng H-F, Blackburn AC, Board PG and Anders MW (2000) Polymorphism- and species-dependent inactivation of glutathione transferase Zeta by dichloroacetate. Chemical Research in Toxicology 13, 231-236.

1999

Anderson WB, Board PG, Gargano B and Anders MW (1999) Inactivation of glutathione transferase Zeta by dichloroacetic acid and other fluorine-lacking a-haloalkanoic acids. Chem Res Toxicol 12, 1144-1149.

Caccuri AM, Antonini G, Board PG, Parker MW, Nicotra M, LoBello M, Federici G and Ricci G (1999) Proton release upon binding of glutathione to Alpha, Mu and Delta class glutathione transferases. Biochemical Journal 344, 419-425.

De Bruin WCC, Wagenmans MJM, Board PG and Peters WHM (1999) Expression of glutathione S-transferase Theta class isoenzymes in human colorectal and gastric cancers. Carcinogenesis 20, 1453-1457.

Flanagan JU, Rossjohn J, Parker MW, Board PG and Chelvanayagam G (1999) Mutagenic analysis of conserved arginine residues in and around the novel sulfate binding pocket of the human Theta class glutathione transferase T2-2. Protein Science 8, 2205-2212.

Kangsadalampai S, Chelvanayagam G, Baker R, Tiedemann K, Kuperan P and Board PG (1999) Identification and characterization of two missense mutations causing factor XIIIA deficiency. British Journal of Haematology 104, 37-43.

Le Couteur DG, McLean AJ, Blackburn AC, Mellick GD and Board PG (1999) Glutathione transferase polymorphism and Parkinson's disease. The Lancet 353, 71-72.

LeCouteur DG., McLean AJ, Taylor M, Woodham B and Board PG (1999) Pesticides and Parkinson's disease. Biomedicine and Pharmacotherapy 53, 122-130.

Polekhina G, Board PG, Gali RR, Rossjohn J and Parker MW (1999) Molecular basis of glutathione synthetase deficiency and a rare gene permutation event. EMBO Journal 18, 3204-3213.

Wempe MF, Anderson WB, Tzeng H-F, Board PG and Anders MW (1999) Glutathione transferase Zeta-catalyzed biotransformation of deuterated dihaloacetic acids. Biochemical and Biophysical Research Communications 261, 779-783.

Whittington AT, Vichai V, Webb GC, Baker RT, Pearson WR and Board PG (1999) Gene structure, expression and chromosomal localization of murine Theta class glutathione transferase mGSTT1-1. Biochemical Journal 337, 141-151.

1998

Blackburn AL, Woollatt E, Sutherland GR and Board PG.(1998) Characterization and chromosome location of the gene GSTZ1 encoding the human ZETA class glutathione transferase and maleylacetoacetate isomerase. Cytogenetic Cell Genetics 83, 109-114.

Board P, Harris M, Flanagan J, Langton L, Coggan M. (1998) Genetic heterogeneity of the structure and function of GSTT2 and GSTP1. Chemico-Biological Interactions 111-112, 83-89.

Board PG. (1998) Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4. Biochemical Journal 330:827-831

Coggan M, Whitbread L, Whittington A and Board PG (1998) The structure and organization of the human Theta class glutathione transferase and D-dopachrome tautomerase gene complex. Biochemical Journal 334, 617-623.

Flanagan JU, Rossjohn J, Parker MW, Board PG, Chelvanayagam G (1998) A homology model for the human Theta-class glutathione transferase T1-1. Proteins 33, 444-454.

Harris MJ, Coggan M, Langton L, Wilson SR and Board PG. (1998) Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients. Pharmacogenetics 8, 27-31

Kangsadalampai S and Board PG (1998) The Val34Leu polymorphism in the A subunit of coagulation factor XIII contributes to the large range in activity and demonstrates that the activation peptide plays a role in catalytic activity. Blood 92, 2766-2770.

Kangsadalampai S, Chelvanayagam G, Baker RT, Yenchitsomanus P-T, Pung-amritt P, Mahasandana C and Board PG. (1998) A novel Asn344 deletion in the core domain of coagulation factor XIII A subunit: its effect on protein structure and function. Blood 92, 481-487.

Menegon A, Board PG, Blackburn AC, Mellick GD, LeCouteur DG (1998) Parkinson's disease, pesticides and glutathione transferase polymorphisms. The Lancet 352, 344-1346.

Nuccetelli M, Mazzettia AP, Rossjohn J, Parker MW, Board P, Caccuri AM, Federici G, Ricci G and Lo Bello M (1998) Shifting substrate specificity of human glutathione transferase (from class Pi to class Alpha) by a single point mutation. Biochemical and Biophysical Research Communications 252, 184-189.

Rossjohn J, McKinstry WJ, Oakley AJ, Verger D, Flanagan J, Chelvanayagam G, Tan K-L, Board PG and Parker MW. (1998) The crystal structure of human theta class glutathione transferase has a sulfate binding pocket within a buried site. Structure 6, 309-322.

Tong Z, Board PG and Anders MW (1998) Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other a-haloacids. Chemical Research in Toxicology 11, 1332-1338.

Tong Z, Board PG and Anders MW. (1998) Glutathione transferase zeta catalyzes the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid. Biochemical Journal 331, 371-374.

Whitbread L, Gali RR, Board PG. (1998) The structure of the human glutathione synthetase gene. Chemico-Biological Interactions 111-112, 35-40.

1997

Board PG, Baker RT, Chelvanayagam G and Jermiin LS (1997) Zeta, a novel class of glutathione transferase in a range of species from plants to humans. Biochemical Journal 328, 929-935.

Caccuri AM, Antonini G, Nicotra M, Battistoni A, Lo Bello M, Board PG, Parker MW and Ricci G. (1997) Catalytic mechanism and role of hydroxyl residues in the active site of Theta class glutathione S-transferases. Journal of Biological Chemistry 272, 29681-29686.

Chelvanayagam G, Wilce MCJ, Parker MW, Tan KL and Board PG. (1997) Homology model for the human GSTT2 Theta class glutathione transferase. Proteins: Structure, Function, Genetics 27, 118-130.

Dahl N, Pigg M, Ristoff E, Gali R, Carlsson B, Mannervik B, Larsson A and Board P. (1997). Missense mutations in the human glutathione synthetase gene result in severe metabolic acidosis, 5-oxoprolinuria, hemolytic anemia and neurological dysfunction. Human Molecular Genetics 6, 1147-1152.

Gali RR and Board PG. (1997) Identification of an essential cysteine residue in human glutathione synthetase. Biochemical Journal 321, 207-210.

1996

Board PG, Gali RR, Vaska V, and Webb G (1996) Molecular genetic characterization of human glutathione synthetase. In: Vermeulen NPE, Mulder GJ, Nieuwenhuyse H, Peters WHM and Van Bladeren PJ (eds.) Gluthione S-Transferases: Structure, Function and Clinical Implications, Taylor & Francis Ltd, London, pp 153-160.

Chelvanayagam G, Wilce MCJ, Parker MW, Tan KL and Board PG (1996) Homology model for the human GSTT2 Theta class glutathione transferase. Proteins: Structure, Function, Genetics 27, 118-130.

Kangsadalampai S, Coggan M, Caglayan H and Board P (1996) Application of HUMF13A01 (AAAG)n STR polymorphism to the genetic diagnosis of coagulation factor XIII deficiency. Thrombosis and Haemostasis 76, 879-882

Kangsadalampai S, Farges-Berth A, Caglayan H and Board, P (1996) New mutations causing the premature termination of translation in the A subunit gene of coagulation factor XIII. Thrombosis & Haemostasis 76, 139-142

Morris C, Jeffs A, Smith T, McDonald M, Board P, Kennedy M, Fitzgerald P (1996) BCR gene recombines with genomically distinct sites on band 11Q13 in complex BCR-ABL translocations of chronic myeloid leukemia. Oncogene 12, 677-685

Rossjohn J, Board PG, Parker MW and Wilce MCJ (1996) A structurally derived consensus pattern for theta class glutathione transferases. Protein Engineering 9, 327-332

Tan K-L, Chelvanayagam G, Parker MW and Board PG (1996) Mutagenesis of the active site of the human Theta class glutathione transferase GSTT2-2: Identification of a novel function as a glutathione dependent sulphatase. Biochemical Journal 319, 315-321.

Tan K-L. and Board PG (1996) Purification and characterisation of a recombinant human Theta class glutathione transferase (GSTT2-2). Biochemical Journal 315, 727-732.

Wagner G, Bhatia K. and Board P (1996) Glucose-6-phosphate dehydrogenase deficiency mutations in Papua New Guinea. Human Biology 68, 383-394

Webb G, Vaska V, Coggan M, and Board P (1996) Chromosomal localization of the gene for the human Theta class glutathione transferase (GSTT1). Genomics 33, 121-123.

Whittington AT, Webb GC, Baker RT and Board PG (1996) Characterization of a cDNA and gene encoding the mouse Theta class glutathione transferase mGSTT2 and its localization to chromosome 10B5-C1. Genomics 33, 105-111

Wilce MCJ, Oakley AJ, Rossjohn J, Feil SC, Lo Bello M, Ricci G, Board PG and Parker MW (1996) Crystallographic Studies of Pi- and Theta-class glutathione transferases.. In: Vermeulen NPE, Mulder GJ, Nieuwenhuyse H, Peters WHM and Van Bladeren P. (eds.) Gluthione S-Transferases: Structure, Function and Clinical Implications, Taylor & Francis Ltd, London, pp 39-48.

1995

Björnestedt R, Stenberg G, Widersten M, Board PG, Sinning I, Jones TA, Mannervik B (1995) Functional significance of arginine15 in the active site of human class Alpha glutathione transferase A1-1. J Mol Biol 247, 765-773

Board PG, Coggan M, Wilce M, and Parker M (1995) Evidence for an essential serine residue in the active site of the Theta class glutathione transferases. Biochem J 311, 247-250

Cameron AD, Sinning I, L'Herrnite G, Olin B, Board PG, Mannervik B, Alwyn Jones T (1995). Structural analysis of human alpha class glutathione transferase A1-1 in the apo form and in complexes with ethacrynic acid and its glutathione conjugate. Structure 3, 717-727

Chenevix-Trench G, Young J, Coggan M, Board P (1995) Glutathione S-transferase M1 and T1 polymorphisms: Susceptibility to colon cancer and age of onset. Carcinogenesis 16, 1655-1657.

Coggan M, Baker R, Miloszewski K., Woodfield G and Board P (1995) Mutations causing coagulation Factor XIII subunit A deficiency: Characterization of the mutant proteins after expression in yeast. Blood 85, 2455-2460.

Gali RR, Board PG (1995) Sequencing and expression of a cDNA for human glutathione synthetase. Biochem J 310, 353-358.

Lo Bello M, Battistoni A, Mazzetti AP, Board PG, Muramatsu M, Federici G, Ricci G (1995) Site Directed Mutagenesis of Human Glutathione Transferase P1-1: Spectral, Kinetic and Structural Properties of CYS-47 and LYS-54 Mutants. J. Biol. Chem. 270, 1249-1253

Tan KL, Webb GC, Baker RT, Board PG (1995) Molecular cloning of a cDNA and chromosomal localization of a human Theta class glutathione S-transferase gene (GSTT2) to chromosome 22. Genomics 25, 381-387.

Webb GC, Vaska VL, Gali RR, Ford JH, and Board PG (1995) The gene encoding human glutathione synthetase maps to the long arm of chromosome 20 at band 11.2. Genomics 30, 617-619.

Wilce MCJ, Board PG, Feil SC, Parker MW (1995) Crystal structure of a Theta-class glutathione transferase. EMBO J. 14, 2133-2143.