Professional Associations

• American Association for Cancer Research
• International Society for the Study of Xenobiotics
• Kathleen Cuningham Foundation Consortium for Research into Familial breast Cancer(kConFab)
• Australian Society for Medical Research

Recent Publications

2007

Blackburn AC, Hill LZ, Roberts AL, Wang J, Aud D, Jung J, Nikolcheva T, Allard J, Peltz G, Otis CN, Cao QJ, Ricketts RS, Naber SP, Mollenhauer J, Poustka A, Malamud D, Jerry DJ. (2007) Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk. Am J Pathol. 170:2030-2041.

Koch JG, Gu X, Han Y, El-Naggar AK, Olson MV, Medina D, Jerry DJ, Blackburn AC, Peltz G, Amos CI, Lozano G. (2007) Mammary tumor modifiers in BALB/cJ mice heterozygous for p53. Mamm Genome. In Press.

2006

Blackburn AC, Matthaei KI, Lim C, Taylor MC, Cappello JY, Hayes JD, Anders MW, Board PG. (2006)
Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways. Mol Pharmacol, 69:650–657.

2005

Schmuck EM, Board PG, Whitbread AK, Tetlow N, Cavanaugh JA, Blackburn AC, Masoumi A. (2005)
Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of Omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimer's and Parkinson's diseases. Pharmacogenet Genomics. 15:493-501.

2004

Board, P.G., Anders, M.W., and Blackburn, A.C., (2004), Catalystic Function and Expression of Glutathione Transerase Zeta. 1 ed. Drug Metabolism and Transport, eds. L.H. Lash: Humana Press Inc. pp. 85-107.

Lim, C.E.L., Matthaei, K.I., Blackburn, A.C., Davis, R.P., Dahlstrom, J.E., Koina, M.E., Anders, M.W., and Board, P.G., (2004), Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of Alpha, Mu, and Pi class glutathione transferases. American Journal of Pathology 165(2), 679-693.

Blackburn AC, McLary SC, Naeem R, Luszcz J, Stockton DW, Donehower LA, Mohammed M, Mailhes JB, Soferr T, Naber SP, Otis CN, Jerry DJ. (2004) Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain.
Cancer Res. 64:5140-7.

2003

Blackburn AC, Brown JS, Naber SP, Otis CN, Wood JT, Jerry DJ (2003). BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/- mice. Cancer Res 63, 2364-8.

2002

Blackburn AC, Jerry DJ (2002) Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer? Breast Cancer Res 4, 101-11.

Jerry DJ, Minter LM, Becker KA, Blackburn AC (2002) Hormonal control of p53 and chemoprevention. Breast Cancer Res 4, 91-4.

Smith SW and Blackburn AC. (2002) Commentary: HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer. Women’s Oncol Rev, 2:37–40.

2001

Blackburn AC, Coggan M, Tzeng H-F, Lantum H, Polekhina G, Marker M, Anders MW and Board PG (2001) GSTZ1d, a new allele of glutathione transferase Zeta and maleylacetoacetate isomerase. Pharmacogenetics 11, 671-678.

Board PG, Chelvanayagram G, Jermiin LS, Tetlow N, Tzeng H-F, Anders MW and Blackburn AC (2001) Identification of novel glutathione transferases and polymorphic variants by expressed sequence TAG database analysis. Drug Metabolism and Disposition 29, 544-547

Polekhina G, Board PG, Blackburn AC and Parker MW (2001) The Crystal Structure of Maleylacetoacetate Isomerase/Glutathione Transferase Zeta reveals the Molecular Basis for its Remarkable Catalytic Promiscuity. Biochemistry 40, 1567-1576

Taylor MC, Board PG, Mellick GD, Blackburn AC and Le Couteur DG (2001) Zeta class glutathione transferase polymorphisms and Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry 70, 406-425.

Tetlow NL, Blackburn AC, Chelvanayagam G and Board PG (2001) Alpha class glutathione transferase polymorphisms identified by EST database analysis. Chemico-Biological Interactions 133, 123-125

More Publications

2000

Blackburn AC, Tzeng H-F, Anders MW and Board PG (2000) Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis. Pharmacogenetics 10, 49-57.

Board P, Tetlow N, Blackburn A, Chelvanayagam G (2000) Database analysis and gene discovery in pharmacogenetics Clin Chem Lab Med 38, 863-867.

Tzeng H-F, Blackburn AC, Board PG and Anders MW (2000) Polymorphism- and species-dependent inactivation of glutathione transferase Zeta by dichloroacetate. Chemical Research in Toxicology 13, 231-236.

1999

Blackburn AC, Doe WF, Buffinton GD (1999) Protein carbonyl formation on mucosal proteins in vitro and in dextran sulfate-induced colitis Free Radical Bio Med 27: 262-270

Le Couteur DG, McLean AJ, Blackburn AC, Mellick GD and Board PG (1999) Glutathione transferase polymorphism and Parkinson's disease. The Lancet 353, 71-72.

1998

Blackburn AC, Woollatt E, Sutherland GR and Board PG.(1998) Characterization and chromosome location of the gene GSTZ1 encoding the human Zeta class glutathione transferase and maleylacetoacetate isomerase. Cytogenetic Cell Genetics 83, 109-114.

Blackburn AC, Doe WF, Buffinton GD (1998) Salicylate hydroxylation as an indicator of hydroxyl radical generation in dextran sulfate-induced colitis. Free Radic Biol Med. 25:305-313

Board P, Blackburn A, Jermiin LS and Chelvanayagam G (1998) Polymorphism of Phase II enzymes: Identification of new enzymes and polymorphic variants by database analysis. Toxicology Letters102-103:149-154

Menegon A, Board PG, Blackburn AC, Mellick GD, LeCouteur DG (1998) Parkinson's disease, pesticides and glutathione transferase polymorphisms. The Lancet 352, 344-1346.

1997

Blackburn AC, Doe WF, Buffinton GD (1997) Colonic antioxidant status in dextran sulfate-induced colitis in mice. Inflammatory Bowel Diseases 3:198-203