Epigenetics and Genome Stability Group
Publications - Dr Danny Rangasamy
2007
Rangasamy D, Tremethick D.J, Greaves I.K (2007). Gene Knockdown
by ecdysone-based inducible RNAi in mammalian cell lines. Nature Protocols
vol. 2 (12)
Zhou J, Fan J, Rangasamy D, Tremethick D.J (2007). The Nucleosome
Surface Regulates Chromatin Compaction and couples it with Transcriptional Repression.
Nature Structural Molecular Biology 14, 1070 – 1076.
Rangasamy D, Greaves K.I, Ridgway P, Tremethick D.J (2007).
H2A.Z contributes to the unique 3D structure of the centromere. Proc.Natl.Acad.Sci.
USA
104 (2), 525-530.
2006
Yang M, Rangasamy D, Frew A.I, Mahalingham S, Webb D.C, Tremethick
D.J, Thompson P.J, Hogen S.P, Matthaei K.I, Rothenberg M.E, Cowden W.B, Foster
P.S (2006). Inhibition of Arginase I activity by RNA interference attenuates
Interleukin-13 induced airways hyperresponsiveness. The Journal of Immunology
177(8) 5595-5603.
Greaves K.I, Rangasamy D, Marshall-Graves J.A, Tremethick
D.J (2006). The X and Y Chromosomes Assemble into H2A.Z-containing Facultative
Heterochromatin, following Meiosis. Molecular and Cellular Biology 26
(14), 5394 – 5405.
2004
Rangasamy D, Fan J, Luger K, Tremethick D.J (2004). H2A.Z alters
the Nucleosome Surface to Promote HP1? mediated Chromatin Fibre Folding. Molecular
Cell
16, 655 – 661.
Ridgway P, Brown K.D, Rangasamy D, Svensson U, Tremethick D.J
(2004). Unique residues on the H2A.Z containing nucleosome surface are important
for Xenopus laevis development. Journal of Biological Chemistry 279,
43815 – 43820.
Bao Y, Konesky K, Park Y.J, Rosu S, Dyer P.N, Rangasamy D,
Tremethick D.J, Laybourn P.J, Luger K (2004). Nucleosomes containing the histone
variant H2A-Bbd organize only 118 base pairs of DNA. EMBO. J 23, 3314
– 3324.
Ridgway P, Rangasamy D, Berven L, Svensson U, Tremethick DJ
(2004). Analysis of histone variant H2A.Z localisation and expression during
early developments.
Methods Enzymology 375, 239-252.
Rangasamy D, Greaves I, Tremethick D.J (2004). RNA interference
Demonstrates a Novel Role for H2A.Z in Chromosome Segregation. Nature Structural
Molecular Biology 11, 650 – 655.
2003
Rangasamy D, Berven L, Ridgway P, Tremethick D.J (2003). Pericentric
Heterochromatin Becomes Enriched with H2AZ during Early Mammalian Development.
EMBO. J 22, 1599 – 1607.
2002
Wilson V.G, West M, Woytek K, Rangasamy D (2002). Papillomavirus
E1 proteins: form, function, and features. Virus Genes 24 (3), 275-290.
2001
Wilson V.G, Rangasamy D (2001). Intracellular Targeting of
Proteins by SUMOylation. Experimental Cell Research 271, 57 –
65.
West M, Flanery D, Woytek K, Rangasamy D, Wilson V.G (2001).
Functional Mapping of the DNA Binding domain of bovine papillomavirus E1 protein.
Journal of Virology 75, 11948 – 11960.
Woytek K, Rangasamy D, Bazaldua-Hernandez C, West M, Wilson
V.G (2001). Effects of mutations within two hydrophilic regions of the bovine
papillomavirus type 1 E1 DNA-binding domain on E1-E2 interaction. Journal
of General Virology 82, 2341 – 2351.
2000
Rangasamy D, Woytek K, Khan S.A, Wilson V.G (2000). SUMO-1
Modification of Bovine Papillomavirus E1 Protein Is Required for Intranuclear
Accumulation.
Journal of Biological Chemistry 275, 37999 – 38004.
Rangasamy D, Wilson V.G (2000). Bovine Papillomavirus E1 protein
is Sumoylated by the Host Ubc9 Protein. Journal of Biological Chemistry
275, 30487 – 30495.
Rangasamy D, Ratledge C (2000). Genetic Enhancement of Fatty Acid Synthesis
by Targeting Rat Liver ATP: citrate lyase into Plastids of Tobacco.
Plant Physiology 122, 1231 – 1236.
Rangasamy D, Ratledge C (2000). Compartmentation of ATP: citrate
lyase in Plants. Plant Physiology 122, 1225 – 1230.