Murphy, J.M., Soboleva, T.A., Mirza, S., Ford, S.C., Olsen, J.E., Chen, J.L., and Young, I.G., 2008, Clarification of the role of N-glycans on the common beta-subunit of the human IL-3, IL-5 and GM-CSF receptors and the murine IL-3 beta-receptor in ligand-binding and receptor activation. Cytokine 42(2), 234-242.

Matthews, C.A., Shaw, J.E., Hooper, J.A., Young, I.G., Crouch, M.F., and Campbell, H.D., 2007, Expression and evolution of the mammalian brain gene Ttyh1. Journal of Neurochemistry 100(3), 693-707.

Wang, J. and Young, I.G., 2007, Eosinophilic inflammation: mechanisms regulating IL-5 transcription in human T lymphocytes. Allergy 62(10), 1131-1138.

Wang, J., Shannon, M.F., and Young, I.G., 2006, A role for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5 transcription in mouse Th-2 lymphocytes. International immunology 18(20), 313-323.

Murphy, J.M. and Young, I.G., 2006, IL-3, IL-5, and GM-CSF signaling: Crystal structure of the human beta-common receptor. Interleukins, eds. G. Litwack. 74: Elsevier Academic Press INC.

Carr, P.D., Conlan, F., Ford, S., Ollis, D.L., and Young, I.G., 2006, An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope. Acta Crystallographica section F-structural biology and crystallization communications 62(509-513 part 6).

Murphy, J.M., Ford, S.C., Olsen, J.E., Gustin, S.E., Jeffrey, P.D., Ollis, D.L., and Young, I.G., (2004), Interleukin-3 Binding to the Murine {beta}IL-3 and Human {beta}c Receptors Involves Functional Epitopes Formed by Domains 1 and 4 of Different Protein Chains. J Biol Chem 279(25), 26500-26508.

2003

Murphy JM, Ford SC, Weidemann UM, Carr PD, Ollis DL and Young IG (2003). A novel functional epitopeformed by domains 1 and 4 of the human common beta -sSubunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5. J Biol Chem 278, 10572-10577.

Yang, M., Hogan, S.P., Mahalingam, S., Pope, S.M., Zimmermann, N., Fulkerson, P., Dent, L.A., Young, I.G., Matthaei, K.I., Rothenberg, M.E., and Foster, P.S., 2003, Eotaxin-2 and IL5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. Journal of Allergy and Clinical Immunology 112(5), 935-943.

Mattes J, Yang M, Mahalingam S, Kuehr J, Webb DC, Simson L, Hogan SP, Koskinen A, Dent L, Rothenberg ME, Matthaei KI, Young IG, Foster PS. (2002). Intrinsic defect in T cell production of Interleukin-13 in the absence of both IL-5 and eotaxin procludes the development of eosinophilia and airways hyperreactivity in experimental asthma. Journal of Experimental Medicine. 195, 1433-1444

Foster PS, Hogan SP, Yang M, Mattes J, Young IG, Matthaei KI, Kumar RK, Mahalingam S, Webb DC. (2002). Interleukin-5 and eosinophils as therapeutic targets for asthma. Trends in Molecular Medicine. 8(4), 162-167

Campbell HD, Fountain S, McLennan IS, Berven LA, Crouch MF, Davy DA, Hooper JA, Waterford K, Chen K-S, Lupski JR, Ledermann B, Young IG, Matthaei K. (2002). Fliih, a Gelsolin-Related Cytoskeletal Regulator Essential for Early Mammalian Embryonic Development. Molecular and Cellular Biology. 22,(10) 3518-3526

Yang M, Hogan SP, Henry PJ, Matthaei KI, McKenzie ANJ, Young IG, Rothenberg ME, Foster PS. (2001). Interluekin-(IL)-13 mediates airways-phase airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin. Am. J. Respiratory Cell & Mol Biol. 25,(4),522-530

Freeman F, Young IG. (2001). Involvement of the sigma receptor in passive-avoidance learning in the day old chick during the second wave of neuronal activity. Neurobiol. Lean Mem. 75, 346-352

Foster PS, Mould AW, Yang M, Mackenzie J, Mattes J, Hogan SP, Mahalingam S, McKenzie ANJ, Rothenberg ME, Young IG, Matthaei KI, Webb DC (2001). Elemental signals regulating eosinophil accumulation in the lung. Immunological Reviews 179, 1-9

Gustin SE, Church AP, Ford SC, Mann DA, Carr PD, Ollis DL, Young IG. (2001). Expression crystallization and derivatization of the complete extracellular domain of the beta c subunit of the human lL-5, lL-3 and GM-CSF receptors. European Journal of Biochemistry. 268, 2905-2911.

Carr PD, Gustin SE, Church AP, Murphy JM, Ford SC, Mann DA, Woltring Dm, Walker I, Ollis DL, Young IG. (2001). Structure of the complete extracellular domain of the common beta subunit of the human GM_CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.. Cell 104, 291-300.

Foster PS, Mould AW, Yang M, Mackenzie J, Hogan SP, Mahalingam S, McKenzie ANJ, Rothenberg ME, Young IG, Matthaei KI, Webb DC. (2001). Elemental signals regulating eosinophil accumulation in the lung. Immunological Reviews. 79,1-9

Robertson SA, Mau VJ, Young IG, Matthaei KI (2000) Uterine eosinophils and reproductive performance in interleukin 5-deficient mice J Reprod Fertil 120: 423-432.

Campbell HD, Young IG & Matthaei KI (2000). Mammalian homologues of the Drosophila melanogaster flightless I gene involved in early development. Current Genomics 1,59-70

Stevceva L, Pavli P, Husband A, Matthaei KI, Young IG, Doe WF (2000) Eosinophilia is attenuated in experimental colitis induced in IL-5 deficient mice Genes Immun 1: 213-218.

Apostolopoulos V, McKenzie IFC, Lees CJ, Matthaei KI & Young IG (2000) A role for IL-5 in the induction of cytotoxic T lymphocytes in vivo. European Journal of Immunology 30, 1733-1739.

Campbell HD, Fountain S, Young IG, Weitz S, Lichter P, Hoheisel JD, Chen KS and Lupski JR (2000) Fliih, the murine homologue of the Drosophila melanogaster flightless-lgene: genomic structure, chromosomal mapping and overlap with Llglh. DNA Sequence 11, 29-40.

Campbell HD, Kamei M, Claudianos C, Woollatt E, Sutherland GR, Suzuki Y, Hida M, Sugano S, Young IG. (2000) Human and Mouse Homologues of the Drosophila melanogaster tweety (tty) Gene: A Novel Gene Family Encoding Predicted Transmembrane Proteins. Genomics 68, 89-92.

Campbell HD, Young IG & Matthaei KI (2000) Mammalian homologues of the Drosophila melanogaster flightless I gene involved in early development. Current Genomics 1, 59-70

Foster PS, Ming Y, Matthaei KI, Young IG, Temelkovski J & Kumar RK (2000) Dissociation of inflammatory and epithelial responses in a murine model of asthma. Laboratory Investigation 80, 655-662. .

Freeman FM, Young IG. (2000) Inhibition of passive-avoidance memory formation in the day-Old chick by the opioid cytochrophin-4. Learning Memory 7, 213-9.

Freeman FM, Young IG. (2000) Identification of the opioid receptors involved in passive-avoidance learning in the day-old chick during the second wave of neuronal activity. Brain Res. 864, 230-9.

Freeman F.M. and Young IG. The Mitochondrial Benzodiazepine Receptor and Avoidance Learning in the Day-Old Chick. Pharmacology Biochemistry and Behavior. 67, 355-362.

Kamei M, Webb GC, Heydon K, Hendry IA, Young IG, Campbell HD. (2000) Solh, the mouse homologue of the Drosophila melanogaster small optic lobes gene: organization, chromosomal mapping, and localization of gene product to the olfactory bulb. Genomics 64, 82-89.

Mould AW, Ramsay AJ, Matthaei KI, Young IG, Rothenberg ME, Foster PS. (2000) The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity. J Immunol. 164, 2142-50.

Vallence BA, Matthaei KI, Sanovic S, Young IG & Collins SM (2000) Interleukin-5 deficient mice suffer impaired host defense during challenge T. spiralis infection. Parasite Immunology. 22, 487-492

Freeman F.M., and Young I.G. (1999) Chloramphenicol-induced amnesia for passive avoidance training in the day-old chick. Neurobiology of Learning and Memory. 71, 80-93.

Tan C.L., Fisher J.A., van Leeuwen B.H., Matthaei K.I., and Young I.G. (1999) Regulation of interleukin-5 expression in T lymphocytes: repression by dexamethasone. In Interleukin-5: From Molecule to Drug Target for Asthma. C.J. Sanderson, Ed., Marcel Dekker, New York.  289-295.

Foster P.S., Hogan S.P., Matthaei K.I., and Young I.G. (1999) The role of interleukin-5 in allergic airways disease.  In Interleukin-5: From Molecule to Drug Target for Asthma. C.J. Sanderson, Ed., Marcel Dekker, New York. 127-135.

Simeonovic C.J., Townsend M.J., Morris C.F., Hapel A.J., Fung M-C., Mann D.A., Young I.G., and Wilson D.J (1999).  "Immune Mechanisms Associated with the Rejection of Fetal Murine Proislet Allografts and Pig Proislet Xenografts:  Comparison of Intragraft Cytokine mRNA Profiles". Cell Transplant 8:365-73.

Simeonovic C.J., Townsend M.J., Karupiah G., Wilson D.J., Zarb J.C., Mann D.A., and Young I.G.  (1999) Analysis of the Th1/Th2 Paradigm in Transplantation: Interferon-Deficiency Converts Th1-Type Proislet Allograft Rejection to the Th2-Type Xenograft-Like Response. Transplantation 67, 963-971.

Vallance B.A., Blennerhassett P.A., Deng Y., Matthaei K.I., Young I.G. and Collins S.M. (1999) IL-5 contributes to, but is not essential for muscle hypercontractility and worm expulsion in a primary T. spiralis infection. Amer. J. Physiol., 277: G400-G408.

Hogan S.P., Koskinen A., Matthaei K.I., Young I. G., and Foster P.S. (1998) Interleukin-5 producing T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity and lung damage in mice.  Am. J. Resp. Crit. Care Med. 157(1): 210-218

Kamei M., Webb G.C., Young I.G., and Campbell H.D. (1998) SOLH, a human homologues of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (Cataract with Microphthalmia). Genomics. (1998) 51: 97-206.

Hogan S.P., Matthaei K.I., Young J.M., Koskinen A., Young I.G., and Foster P.S. (1998) "A Novel T-cell Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently Of Interleukin -4 and -5". J. Immunology 161(3) : 1501-1509.

Bao S., Beagley K.W., Caristo V., Matthaei K.I., Young I.G., and Husband A.J. (1998) Intestinal IgA Plasma cells of the B-1 lineage are IL-5 dependent. J. Immunology. 94: 181-188.

Hogan S.P., Mould A.W., Young JM., Rothenberg M., Ramsay A.J. Matthaei K.I. Young I.G. and Foster P.S. (1998) "Cellular and Molecular Regulation of Eosinophil Trafficking to the Lung", Immunology and Cell Biology 76, 454-460

Ovington K.S., McKie K., Matthaei K.I., Young I.G. and Behm C.A. (1998) Regulation of primary Strongyloides ratti infections in mice: a role for interleukin-5. Immunology 95: 488-93.

Simeonovic C.J., Townsend M.J., Wilson J.D., McKenzie K.U.S., Ramsay A.J., Matthaei K.I., Mann D.A., and Young I.G. (1997) Eosinophils are not required for the rejection of neovascularised fetal pig proislet xenografts in mice.l J. Immunol. 158: 2490-2499

Mould A.W., Matthaei K.I., Young I.G., and Foster P.S. (1997) Relationship between Interleukin-5 and Eotaxin in regulating blood and tissue eosinophilia in mice. J. Clin. Invest. 99: 1064-1071

Takamoto M., Ovington K.S., Behm C.A., Sugane K., Young I.G., and Matthaei K.I. (1997) Eosinophilia, parasite burden and lung damage in Toxocara canis infection in C57Bl/6 mice genetically deficient in IL-5 . J. Immunology. 90: 511-517

Jans D.A., Briggs L.J., Gustin S.E., Jans P., Ford S., and Young I.G. (1997) A functional bipartite nuclear localization signal in the cytokine interleukin-5. FEBS Letters. 406: 315-320

Campbell H.D., Fountain S., Young I.G., Claudianos C., Hoheisel J.D., Chen K-S., and Lupski J.R. (1997) Genomic structure, evolution and expression of human a FLI, a gelsolin and leucine-rich-repeat family member: overlap with LLGL. Genomics. 42: 46-54

Campbell H.D., Webb G.C., Fountain S., and Young I.G. (1997) The human PIN1 peptidyl-prolyl cis/trans isomerase gene maps to human chromosome 19p13 and the closely related PIN1L gene to 1p31. Genomics. 44: 157-162

Campbell H.D., Webb G.C., and Young I.G. (1997) A human homologue of the Drosophila melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-1 hyperprolinaemia. Hum. Genet. 101: 69-74

Whittle B.L., Smith R.M., Matthaei K.I., Young I.G., and Verma N.K. (1997) Enhancement of the specific mucosal IgA response in vivo by interleukin-5 expressed by an attenuated strain of Salmonella serotype Dublin. J. Med. Microbiol. 46(12): 1029-1038

Jans D.A., Briggs L.J., Gustin S.E., Jans P., Ford S., and Young I.G. (1997) The cytokine interleukin-5 (IL-5) effects of cotransport of its receptor subunits to the nucleus in vitro. FEBS Letters. 410: 368-372

Matthaei K.I., Foster P.S., and Young I.G. (1997) The role of IL-5 in vivo: studies with IL-5 deficient mice. Memorias do Instituto Oswaldo Cruz. 92: 63-68

Foster P.S., Hogan S.P., Matthaei K.I., Young I.G.(1997) Interleukin-4 and Interleukin-5 as targets for the inhibition of eosinophilic inflammation and allergic airways hyperreactivity. Memorias do Instituto Oswaldo Cruz. 92: 55-62

Kopf M., Brombacher F., Hodgkin P.D., Ramsay A.J., Milbourne E.A., Dai W.J., Ovington K.S., Behm C.A., Kohler G., Young I.G., and Matthaei K.I. (1996) IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses.  J. Immunity. 4: 15-24

Foster P.S., Hogan S.P., Ramsay A.J., Matthaei K.I., and Young I.G. (1996) Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.  J. Exp. Med. 183: 195-201

Ramsay A.J., Bao S., Beagley K.W., Dunstan S.J., Husband A.J., Kopf M., Matthaei K.I., Ramshaw I.A., Strugnell R.A., Young I.G., and Tan X. (1996) Cytokine Gene Knockout Mice - Lessons for Mucosal B Cell Development.  In: Essentials of Mucosal Immunology, (Kagnoff M and Kiyono H, eds), pp247-259, Academic Press

Naora H., and Young I.G. (1995) Comparison of the mechanisms regulating IL-5, IL-4 and four other lymphokine genes in the Th2 clone D10.G4.1. Exp Haematology.  23: 597-602

Chen K.S., Nguyen D., Hoheisil J., Young I.G., Miklos G.L.G., Greenberg F., Schaffer L.G., Campbell H.D., and Lupski J.R. (1995) The human homologue of the Drosophila melanogaster Flightless-I gene (FliI) maps within the Smith-Magenis microdeletion critical region in 17p11.2. Amer. J. Human Genetics. 56 175-182

Bourke P.F., van Leeuwen B.H.., Campbell H.D., and Young I.G. (1995) Localisation of the inducible inhancer in the mouse interleukin-5 gene which is responsive to T cell receptor stimulation.  Blood. 85: 2069-2077

Naora H., Altin J.G., and Young I.G. (1994) T cell receptor-dependent and -independent signalling mechanisms differentially regulate lymphokine gene expression in the murine T helper clone D10.G4.1. J. Immunol. 152: 5691-5702

Naora H., and Young I.G. (1994) Mechanisms regulating the mRNA levels of IL-5 and two other coordinately expressed lymphokines in the murine T lymphome EL4.23. Blood 83: 3620-3628

Naora H., Bourke P.F., van Leeuwen B.H., and Young I.G. (1994) Functional role and signal-induced modulation of proteins recognizing the conserved TCATTT-containing promoter elements in the murine IL-5 and GM-CSF genes in T lymphocytes. J. Immunol. 153: 3466-3475