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The Australian National University
The John Curtin School of Medical Research
ANU COLLEGE OF MEDICINE AND HEALTH SCIENCES

Dr Mark Hulett - Publications

2008

Wood, R. J., and Hulett, M. D. (2008). Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation. J Biol Chem 283(7), 4165-76.

2007

de Mestre, A.M., Staykova, M.A., Hornby, J.R., Willenborg, D.O., and Hulett, M.D., 2007, Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4(+) T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1. Journal of Leukocyte Biology 82(5), 1289-1300.

de Mestre, A. M., Soe-Htwe, T., Sutcliffe, E. L., Rao, S., Pagler, E. B., Hornby, J. R., and Hulett, M. D. (2007). Regulation of mouse Heparanase gene expression in T lymphocytes and tumor cells. Immunol Cell Biol 85(3), 205-14.

2006

Abby, J.L., Hulett, M.D., and O'Neill, H., 2005, Cell surface expression of a peptide encoded
by the un-rearranged TCR-Vbeta 8.2 gene. Molecular Immunology 43:1408-17.

Forbes, E., Hulett, M.D., Ahens, R., Smart, V., Matthaei, K.I., Brandt, E., Rothenberg, M.E., Tang, M., Foster, P.S. and Hogan, S.P. 2006. ICAM-1 dependent pathways regulate colonic eosinophilic inflammation.
J. Leuk. Biol. 80(2), 330-341.

 

2005

de Mestre, A.M, Rao, S., Hornby, J.R., Soe Htwe, Khachigian, L.M. and Hulett M.D. 2005. EGR1 regulates heparanase gene transcription in tumour cells. J. Biol. Chem. 280:35136-35147.

Jones, A.L., Poon, I., Hulett, M.D. and Parish, C. R. 2005. Histidine-rich glycoprotein specifically binds to necrotic cells, via its amino-terminal domain, and facilitates necrotic cell phagocytosis. J. Biol. Chem. 280:35733-35741.

Jones, A.L., Hulett, M.D., and Parish, C.R., (2005), Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems. Immunology and Cell Biology 83(2), 106-118.

2004

Jones, A.L., Hulett, M.D., Altin, J.G., Hogg, P., Parish, C.R., (2004), Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein. Journal of Biological Chemistry 279(37), 38267-38276.

Jones, A.L., Hulett, M.D., and Parish, C.R., (2004), Histidine-Rich Glycoprotein Binds to Cell Surface Heparan Sulfate via its Amino-Terminal Domain Following Zn2+ Chelation. J Biol Chem 279(29), 30114-30122.

 

2003

Mattes J, Hulett M, Xie W, Hogan S, Rothenberg ME, Foster P and Parish C (2003). Immunotherapy of cytotoxic T cell resistant tumors by T helper 2 cells: an eotaxin and STAT6 dependent process. J Exp Med 197, 387-393.

deMestre AM, Khachigian LM, Santiago FS, Staykoba A and Hulett MD (2003) Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1. J Biol Chem. 278(50), 50377-50385


2002

Mackay GA, Hulett MD, Cook JP, Trist HM, Henry AJ, Beavil AJ, Beavil RL, Sutton BJ, Hogarth PM and Gould HJ (2002) Mutagenesis within human FceRIa differentially affects human and murine IgE. J Immunol. 168, 1787-1795.

Vlodavsky I, Friedmann Y, Elkin M, Pappo O, Hulett MD, Parish CR and Freeman C (2002) Mammalian heparanase: Molecular properties,inhibition and involvement in tumour metastasis and angiogenesis. In:Cancer Metastasis, Biology and Treatment (Editors J-M Foidat and R Muschel), Kluwer, NY. Vol 4, 225-250.

2001

Freeman C, Hulett MD and Parish CR (2001) Heparanase. In: Encyclopedia of Molecular Medicine. Vol.3 (ed Claret L) John Wiley and Sons, New York pp 1582-1585.

Hulett MD, Pagler E, Hornby JR, Hogarth PM, Eyre HJ, Baker E, Crawford J, Sutherland GR, Ohms SJ and Parish CR (2001) Isolation tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-Beta. Biochemical and Biophysical Research Communications 280, 374-379.

Hulett MD, Pagler E, Hornby JR (2001) Cloning and characterisation of a mouse homologue of the human hematopoietic cell-specific four-transmembrane gene HTm4. Immunology and Cell Biology 79, 345-349.

Parish CR, Freeman C and Hulett MD (2001) Heparanase: a key enzyme involved in cell invasion. Biochimica et Biophysica Acta 1471, M99-M108.


2000

Hulett MD, Hornby JR, Ohms J, Zeugg J, Freeman C, Gready JE and Parish CR (2000) Identification of active site residues of the pro-metastatic endoglycosidase heparanase. Biochemistry 39, 15659-15667

Hulett MD and Parish CR (2000) Murine histidine-rich glycoprotein: Cloning, characterisation and cellular origin. Immunology and Cell Biology 78,280-287.

Rigby LJ, Chandana EV, Mackay GA, Hulett MD, Sutton BJ, Gould HJ and Hogarth PM (2000) Domain one of the high affinity IgE receptor FcepsilonRI, regulates binding to IgE through its interface with domain two. Journal of Biological Chemistry 275, 9664-9672.

Rigby LJ, Trist H, Snider J, Hulett MD, Hogarth PM and Epa VC (2000) Monoclonal antibodies and synthetic peptides define the active site of FcepsilonRI and a potential receptor antagonist. Allergy 55, 609-619.

1999

Baker E, Crawford J, Sutherland GR, Freeman C, Parish CR and Hulett MD (1999) Human Hpa. Endoglycosidase heparanase Map position 4q21.3. Chromosome Research 7, 319.

Hulett MD, Freeman C, Hamdorf BJ, Baker RT, Harris MJ and Parish CR (1999) Cloning of mammalian heparanase A key enzyme in tumour invasion and metastasis. Nature Medicine 5, 803-809.

Hulett MD, Witort E, Brinkworth R, McKenzie IFC and Hogarth PM (1999) Fine structure analysis of the interaction of FceRI with IgE. Journal of Biological Chemistry 274, 13345-13352.

Maxwell KF, Powell MS, Hulett MD, Barton PA, McKenzie IFC, Garrett TPJ and Hogarth PM (1999) Crystal structure of the human leukocyte Fc receptor, FcgammaRIIa. Nature Structural Biology 6, 437-442.

Wines BD, Hulett MD, Jameison GP, Trist H, Spratt J and Hogarth PM(1999) Identification of residues in the first domain of Human Fc alpha are essential for interaction with IgA. Journal of Immunology 162, 2146-2153.