Dr
Dianne Webb- Publications
2007
Webb, D. C., Otczyk, D. C., and Cripps, A. W. (2007).
Investigation of the potential of a 48kDa protein as a vaccine candidate
for infection against nontypable Haemophilus influenzae. Vaccine 25(20),
4012-9.
Webb, D.C., Cai, Y.P., Matthaei, K.I., and Foster, P.S.,
2007, Comparative roles of IL-4, IL-13, and IL-4R alpha in dendritic cell
maturation and CD4(+) Th2 cell function. Journal of Immunology 178(1),
219-227.
2006
Yang, M., Rangasamy, D., Matthaei, K.I., Frew, A.J., Zimmmermann, N.,
Mahalingam, S., Webb, D.C., Tremethick, D.J., Thompson,
P.J., Hogan, S.P., Rothenberg, M.E., Cowden, W.B., and Foster, P.S., 2006,
Inhibition of Arginase I Activity by RNA Interference Attenuates IL-13-Induced
Airways Hyperresponsiveness. Journal of Immunology 177(8), 5595-5603.
Kumar, R.K., Webb, D.C., Herbert, C., and Foster, P.S.,
2006, Interferon-gamma as a Possible Target in Chronic Asthma. Inflamm
Allergy Drug Targets 5(4), 253-6.
2004
Webb, D.C., Matthaei, K.I., Cai, Y.P., McKenzie, A.N.J.,
and Foster, P.S., (2004), Polymorphisms in IL-4R alpha correlate with
airways hyperreactivity, eosinophilia, and Ym protein expression in allergic
IL-13(-/-) mice. Journal of Immunology 172(2), 1092-1098.
Kumar, R.K., Herbert, C., Webb, D.C., Li, L., and Foster,
P.S., (2004), Effects of anticytokine therapy in a mouse model of chronic
asthma. American Journal of Respiratory and Critical Care Medicine 170(10),
1043-1048.
2003
Webb DC, Mahalingam S, Cai Y, Matthaei KI, Donaldson DD, Foster
PS. (2003). Antigen-specific production of interleukin (IL)-13
and IL-5 cooperate to mediate IL-4Ralpha-independent airway hyperreactivity. Eur.
J. Immunol, 33, :3377-3385.
Kumar, RK; Herbert, C; Thomas, PS; Wollin, L; Beume, R; Yang, M; Webb,
DC; Foster, PS. (2003). Inhibition of inflammation and remodeling
by roflumilast and dexamethasone in murine chronic asthma. .J. Pharm.
Exp. Ther. 307, 349-355.
Foster PS, Webb DC, Yang M, Herbert C, Kumar RK (2003). Dissociation
of Th 2 cytokine-dependent airway lesions from STAT6 signalling in experimental
chronic asthma. Clin. Exp. Allergy. 3, 688-695.
2002
Mattes J, Yang M, Mahalingam S, Kuehr J, Webb DC, Simson L, Hogan
SP, Koskinen A, McKenzie AN, Dent LA, Rothenberg ME, Matthaei KI, Young
IG, Foster PS., (2002). Intrinsic defect in T cell production
of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes
the development of eosinophilia and airways hyperreactivity in experimental
asthma. J. Exp. Med.. 195(11):1433-1444.
Foster PS, Hogan SP, Yang M, Mattes J, Young IG, Matthaei KI, Kumar
RK, Mahalingam S, Webb DC., (2002). Interleukin-5 and
eosinophils as therapeutic targets for asthma. Trends Mol. Med.
8(4):162-167.
2001
Webb DC, McKenzie AN, Foster PS., (2001). Expression of
the Ym2 lectin-binding protein in the allergic lung is dependent on interleukin
(IL)-4 and IL-13 signal transduction: Identification of a novel
allergy-associated protein. J. Biol. Chem. 276(45):41969-41076
Mattes J, Yang M, Siqueira A, Clark K, MacKenzie J, McKenzie AN, Webb
DC, Matthaei KI, Foster PS., (2001). Interleukin-13 induces
airways hyperreactivity independently of the IL-4R alpha chain in the
allergic lung. J. Immunol. 167(3):1683-1692.
Harris RM, Webb DC, Howitt SM, Cox GB., (2001. )Characterization
of PitA and PitB from Escherichia coli. J. Bacteriol. 183(17):5008-5014
Zuegg J, Webb DC, Foster PS, Casarotto MG., (2001). A structural
model of human IL-13 defines the spatial interactions with the IL-13Ralpha/IL-4Ralpha
receptor. Imm. Cell Biol. ; 79(4):332-339.
oster PS, Mould AW, Yang M, Mackenzie J, Mattes J, Hogan SP, Mahalingam
S, Mckenzie AN, Rothenberg ME, Young IG, Matthaei KI, Webb DC.,
(2001). Elemental signals regulating eosinophil accumulation
in the lung. Immun. Reviews. 179;1-9.
Webb DC, McKenzie AN, Matthaei KI, Rothenberg ME, Foster PS.,
(2001). Distinct spatial requirement for eosinophil-induced airways
hyperreactivity. Imm. Cell Biol. 79(2):165-169. (invited special
feature)
2000
Webb DC, Andrew N, McKenzie J, Koskinen AM, Yang M, Mattes J,
Foster PS., (2000). Integrated signals between( IL)-13, IL-4, and IL-5
regulate airways hyperreactivity. J. Immunol. 165(1):108-113.
Webb DC, Cripps AW., (2000). A P5 peptide that is
homologous to peptide 10 from Pseudomonas aeruginosa enhances clearance
of nontypeable Haemophilus influenzae from acutely infected rat
lung in the absence of detectable peptide-specific antibody. Infect Immun.
68(1):377-381
1999
Webb DC, Foster PS., (1999). The use of murine models
to investigate the immune networks underlying asthama. Curr Opin Anti-Inflamm
and immunomod Drugs 1, 433-441 (invited review)
Webb DC, Cripps AW., (1999). Immunization with recombinant
transferrin binding protein B enhances clearance of nontypeable Haemophilus
influenzae in a rat pulmonary model. Infect Immun. 67(5):2138-2144.
Webb DC, Cripps AW., (1999). A method for the purification
and refolding of a recombinant form of the nontypeable Haemophilus influenzae
P5 outer membrane protein fused to poly-histidine. Prot. Exp Purif. 15(1):1-7.
1998
Webb DC, Cripps AW., (1998). Secondary structure and molecular
analysis of interstrain variability in the P5 outer-membrane protein of
non-typable Haemophilus influenzae isolated from diverse anatomical
sites. J. Med. Microbiol. 47(12):1059-1067. |