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Dr Gerard Hoyne - Recent Publications

1. Hoyne, G. F. and Goodnow, C. C. The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity. Immunological Reviews 210, 27-39.
   
2. Hoyne, G. F.,(2003). Notch signalling in the immune system. J. Leuk. Biol.74: 971-981
   
   
3. Wong, K., Carpenter, MJ., Young, L.L., Platt, AJ., Walker, SJ., McKenzie, G., Rust, AJ.,Ward, G., Packwood, L., Wahl, K., Delriviere, L., Hoyne, GF, Gibbs, P., Champion, BR., Lamb, J. R., and Dallman M.J. (2003) Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell dependent mechanism. J. Clin Invest.112: 1741-1750.
   
   
4. Papathanasiou, P, Perkins, A.C., Cobb, B.S., Ferrini, R., Sridharan, Hoyne, GF., R., Nelms, K.A., Smale, S.T., Goodnow, C.C. (2003). A broad role for Ikaros in blood cell differentiation revealed by an ENU-induced point mutation. Immunity 19:131-144.
   
   
5. Hoyne, G. F., Dallman, M. J., Champion, B. R. and Lamb, J. R. (2001). Notch signalling and the regulation of peripheral immunity. Immunological Reviews 182: 215-227
   
   
6. Stewart, G. Hoyne, G. F.,Ahmad, S., Jarman , E. R., Wallace WAH, Harrison, DJ, Haslett, C., Lamb, J. R., Howie, S. E. (2003) Expression of the developmental Sonic hedgehog [Shh] signalling pathway is upregulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes J. Path 199:488-495.
   
   
7. Lowrey, J., Stewart, G. A., Lindey, S., Forsyth, L.M.G., Hoyne, G. F., Hayley, S., Lamb, J. R., Howie, S. E., (2002) Shh promotes expansion of peripheral CD4+ T cell following suboptimal TCR signalling J. Immunol. 169: 1869-1875.
   
   
8. Hoyne, G. F., Le Roux, I., Corsin-Jimenez, M., Tan, K., Dunne, J., Forsyth, L. M., Dallman, M. J., Owen, M. J., Ish-Horowicz, D., & Lamb, J. R. (2000). Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells. Int Immunol 12, 177.
   
   
9. Hoyne G.F., Dallman M.J. & Lamb J.R. (1999) Linked suppression in peripheral T cell tolerance to the house dust mite derived allergen Der p 1. Int Arch Allergy Immunol, 118, 122
   
   
10. Jones P., May G., Healy L., Brown J.,Hoyne G.F.,Delassus S. & Enver T. (1998) Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells. Blood, 92, 1505.