The skeletal muscle plasma membrane and store-operated Ca2+ entry

Friday 10 August 2012

Dr Bradley Launikonis is a senior lecturer and Head of the Muscle Research Lab at The University of Queensland. The main interest of the lab is Excitation-Contraction Coupling and Calcium Regulation in Skeletal Muscle. The focus is to understand the mechanisms that (i) control calcium release during activity in muscle, and (ii) maintain calcium homeostasis in skeletal muscle fibres. Within this broad focus, the roles of ion channels, pumps and membrane lipid composition in skeletal muscle physiology are studied. Significant emphasis is given to how properties of the muscle change in disease and other stressed states. To unravel the physiological mechanisms that control skeletal muscle activity, imaging of muscle cell structures and calcium movements are performed.

 

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