Professor Charles Mackay, Department of Immunology, Monash University.
Charles Mackay is an immunologist working on the molecular basis of immune responses, particularly inflammatory responses. His research focuses on mechanisms of cell migration, and cytokines and chemokines for immune responses. His research has considerable relevance to applied outcomes for immunological diseases, including new monoclonal antibody treatments for inflammation, fibrosis and cancer. Charles Mackay delineated pathways by which subsets of T cells recirculate through the body, and also discovered and characterised chemoattractant receptors for important inflammatory immune cells such as CCR3 and CCR5. Mackay’s recent work has uncovered molecules and receptors responsible for gut homeostasis, and he is the chief proponent of a ‘diet hypothesis’ to explain the increased incidence of inflammatory diseases in western countries.
Charles Mackay did his Ph.D at Melbourne University, and worked at the Basel Institute for Immunology, LeukoSite Inc. and Millennium Therapeutics in Boston USA, and Garvan Institute in Sydney, before moving to Monash University in mid 2009. Charles Mackay is a fellow of the Australian Academy of Science, is an ISI highly cited author, H-index 75, >23000 citations, and has published over 140 papers.