JCSMR School Seminar Series - Managing CD8+ T cell identity

Professor Hai-Hui Xue, Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, USA

CD8+ T cells are dedicated cytotoxic lymphocytes, and their identity must be tightly regulated during development and activation processes. The underlying mechanisms involve both transcriptional and epigenetic regulators. The interplay of Tcf, Runx and Tle factors will be discussed.

Dr. Hai-Hui (Howard) Xue is a Professor of Microbiology and Immunity at the University of Iowa, USA. He obtained his Ph.D., majoring in biochemistry, in Japan and did postdoctoral training in molecular immunology at the National Institutes of Health, USA.

His research laboratory is interested in transcriptional and epigenetic regulation of T cell development in thymus, and T cell differentiation in response to viral infection. His recent work focuses on the Wnt-T cell factor 1 pathway and has revealed its multifaceted functions from programming memory T cell formation and controlling self-renewal of leukemic stem cells.

Date & time

12–1pm 16 March 2018


The Finkel Lecture Theatre, The John Curtin School of Medical Research, Builidng 131 Garran Road, ANU


 Nora Jain
 +61 2 6125 4996

Updated:  24 March 2018/Responsible Officer:  Director, JCSMR/Page Contact:  Web Manager