Patrick Tam is the Deputy Director and Head of the Embryology Research Unit at the Children's Medical Research Institute. He is a Senior Principal Research Fellow of the National Health and Medical Research Council of Australia, and holds a conjoint appointment as Professor in the Discipline of Medicine at the Sydney Medical School, The University of Sydney. His research focuses on the elucidation of the cellular and molecular mechanisms of body patterning during embryonic development. Major effort is aimed at the understanding of the integration of the molecular control of gene activity and the signalling activity that mediates cell-cell communication and the coordination of cell differentiation in the formation of organs and major body parts. The knowledge gleaned from the embryological analysis and cell lineage investigation is applied for the enabling of directed differentiation of embryo-derived and induced pluripotent stem cells for regenerative and genetic therapy of developmental disorders of endodermal organs such as the liver and the pancreas.
Patrick Tam is an Editor of Development and member of the editorial board of journals on developmental biology including Developmental Cell and Developmental Biology. He is a Guest Editor of BioEssays and Current Opinion of Genetics and Development and a Co-editor (with James Nelson and Janet Rossant) of the book “Mamalian Development” to be published by Cold Spring Harbor Press in 2013. Patrick Tam is the Mok Hing-Yiu Distinguished Visiting Professor of the Li Ka Shing Faculty of Medicine at the University of Hong Kong. He was awarded the Croucher Foundation Fellowship tenured at Oxford University (1986), the Symington Memorial Prize of the Anatomical Society of Great Britain and Ireland (1987), and the President’s Medal of the Australian and New Zealand Society of Cell and Developmental Biology (2007), and elected Fellow of the Australian Academy of Science, the Institute of Biology UK, the Society of Biology and the Royal Society of London.